Monday, February 18, 2019

One-Pot, Modular Approach to Functionalized Ketones via Nucleophilic Addition/Buchwald-Hartwig Amination Strategy

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C8CC08444K, Communication
Jorn de Jong, Dorus Heijnen, Hugo Helbert, Ben L Feringa
A general one-pot procedure for the 1,2-addition of organolithium reagents to amides followed by the Buchwald-Hartwig amination with in-situ released lithium amides is presented. In this work amides are used...
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