Monday, November 15, 2021

Facile synthesis of novel Bi(0)-SBA-15 adsorbents by an improved impregnation reduction method for highly efficient capture of iodine gas

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J Hazard Mater. 2021 Nov 7;424(Pt C):127678. doi: 10.1016/j.jhazmat.2021.127678. Online ahead of print.

ABSTRACT

Development of high efficient adsorbents to capture iodine is of great significance for the active development of nuclear power. Herein, Bi0-SBA-15 was firstly synthesized and applied for capture of iodine gas. Bi0-SBA-15 materials were prepared by an improved impregnation reduction method. The benefit of this method was that the Bi0 nano particles with flocculent and spherical morphologies were loaded on the surface of SBA-15, which provide abundant active sites for iodine and improve the utilization rate of active sites, so as to attain a record high capture capacity (up to 925 mg/g within 60 min) and high stablitiy (91.2%) at 200 °C. The results demonstrated that the loading of Bi0 on the surface showed a significant impact on the structure of Bi0-SBA-15 and did greatly enhance the iodine capture. Furthermore, the high iodine capture capacity mainly derived from the chemical adsorption in the stable form of BiI3. The obtained Bi0-SBA-15 materials exhibited excellent aqueous and irradiation stability. Thus, the results indicated that the new and highly efficient Bi0-SBA-15 was a potential radioactive iodine gas capture material.

PMID:34775310 | DOI:10.1016/j.jhazmat.2021.127678

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Reconstruction of fingertip defects with the anterograde homodigital neuroarterial island flap under local anesthesia

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J Plast Reconstr Aesthet Surg. 2021 Oct 22:S1748-6815(21)00486-1. doi: 10.1016/j.bjps.2021.09.045. Online ahead of print.

NO ABSTRACT

PMID:34774444 | DOI:10.1016/j.bjps.2021.09.045

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A reverse form of Linburg-Comstock variation with comments on its etiology and demonstration of interactive 3D portable document format

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Surg Radiol Anat. 2021 Nov 13. doi: 10.1007/s00276-021-02858-8. Online ahead of print.

ABSTRACT

PURPOSE: Two most common variations of flexor pollicis longus include its accessory head and its connection with the flexor digitorum profundus of the index (Linburg-Comstock variation). In addition, while three-dimensional (3D) screening has widely been used in anatomical education, its use as reporting tool in anatomical research is still limited. The objective of this study is to report a previously unrecognized form of the accessory head of flexor pollicis longus, discuss the potential etiology of Linburg-Comstock variation, and pilot the 3D scanning of a large-scale anatomical structure.

METHODS: An unusual tendon slip was discovered during a routine dissection in the anterior compartment of the right forearm of a 54-year-old male cadaver. A 3D scanner was used to capture the surface topography of the specimen and an interactive portable document format (PDF) was created.

RESULTS: An anomalous tendon was found originating from the lateral aspect of the flexor digitorum profundus muscle. This variant tendon then inserted onto the medial surface of the flexor pollicis longus tendon before entering the carpal tunnel. The variation resembles a reverse form of Linburg-Comstock variation, because pulling this variant tendon resulted in simultaneous flexion of the interphalangeal joint of thumb.

CONCLUSION: Surgeons should be aware of the rev erse Linburg-Comstock variation, because it may not be detectable by the conventional provocative testing. Linburg-Comstock variation may be classified as an anatomical variant or a secondarily acquired condition depending on its type. Our demonstration of interactive 3D-PDF file highlights its potential use for delivering anatomical information in future cadaveric studies.

PMID:34775526 | DOI:10.1007/s00276-021-02858-8

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Localization of the neuropeptide manserin in rat dorsal root ganglia: Involvement in nociceptive function

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Acta Histochem. 2021 Nov 11;123(8):151812. doi: 10.1016/j.acthis.2021.151812. Online ahead of print.

ABSTRACT

Manserin, a neuropeptide discovered in the rat brain, is distributed in the spiral ganglion of the inner ear and carotid body, suggesting it is also localized in another neuron cluster. In this study, we examined manserin's localization in the dorsal root ganglion (DRG) and spinal cord of adult Wistar rats using immunohistochemical analyses. The DRG consists of neuro filament (NF) 200-positive large cells and two types of small cells (calcitonin gene-related peptide (CGRP)-positive peptidergic neurons and isolectin B4 (IB4)-positive non-peptidergic neurons). Manserin was localized in some of the small cells. Fluorescence double immunostaining showed that manserin-positive cells corresponded to some of the CGRP-positive cells. The DRG comprises pseudo-unipolar cells that receive sensory information from the skin and viscera and project to each layer of the dorsal horn of the spinal cord. Manserin was localized in the CGRP-positive layer I and II outer, but not in the IB4-positive layer II inner. These results suggest manserin is localized in CGRP-positive cells in the DRG, projects to the dorsal horn of the spinal cord, and is secreted with other neuropeptides, such as CGRP, to participate in nociceptive function.

PMID:34775224 | DOI:10.1016/j.acthis.2021.151812

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Ramadan fasting during treatment with external beam radiotherapy

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Bull Cancer. 2021 Nov 11:S0007-4551(21)00304-0. doi: 10.1016/j.bulcan.2021.05.010. Online ahead of print.

ABSTRACT

INTRODUCTION: Many Muslim cancer patients insist on fasting during the month of Ramadan, even during treatment. The purpose of this observational study is to study the practice of fasting, in patients receiving external radiation therapy.

METHODS: Our study was conducted during the month of Ramadan 1441 (2018) in the radiotherapy department of Ibn Rochd University Hospital of Casablanca. We included all patients who received external radiotherapy during this period. We thus collected the characteristics of patients, disease and treatment modalities. After an interview, with a pre-established questionnaire, we were able to establish the observance of the fast.

RESULTS: We collected a total of 209 patients. The most frequently represented locations were breast cancer followed by gynecological cancers in 35.4% and 18.7% respectively. All our patients were fasting Ramadan before the diagnosis of cancer, however, only 39.2% were fasting during the treatment by radiotherapy, and just 40% of patients have discussed the possibility of fasting with their oncologist. In multivariate analysis, the stage of the disease was the only factor related to the fasting status of our patients.

DISCUSSION: Even under treatment, many of our patients fast during the month of Ramadan. Further studies are needed to evaluate the tolerance of fasting in order to better answer the question "can I fast?".

PMID:34776116 | DOI:10.1016/j.bulcan.20 21.05.010

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Moxetumomab pasudotox-Third line in Hairy cell leukemia

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Bull Cancer. 2021 Nov 11:S0007-4551(21)00378-7. doi: 10.1016/j.bulcan.2021.07.011. Online ahead of print.

NO ABSTRACT

PMID:34776118 | DOI:10.1016/j.bulcan.2021.07.011

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Medicinal plants used by patients to fight cancer

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Bull Cancer. 2021 Nov 11:S0007-4551(21)00441-0. doi: 10.1016/j.bulcan.2021.09.017. Online ahead of print.

ABSTRACT

Cancer is among the deadliest diseases in the world, especially in developed countries where modern treatments are not available to everyone. In North Africa, and especially in Algeria, few herbal treatments against cancer have been documented despite the richness of flora in these countries. This research aim to documents the medicinal plants used by patient to fight cancer in the northwest of Algeria. Data were collected through ethnobotanical surveys engaging 211 cancer patients in hospitals (departments of medical oncology) in two of the largest provinces in northwest Algeria (Tiaret and Tlemcen). The data were organized into usage reports (UR), while the Informant Consensus Factor (ICF) was calculated to evaluate agreement among informants. The patients investigated were mainly women, of middle age (41-50 years) and i lliterate. In total, 53 medicinal plants used against several types of cancer have been identified. These plants are dominated by Lamiaceae, Apiaceae and Rosaceae. The leaves and powder of plants are most often used in traditional preparations often mixed with honey. The plants most often cited in the survey were Aristolochia longa, Aquilaria malaccensis, Ephedra alata subsp. alenda, while the most often treated cancer were breast, cervical, colorectal and stomach. 23 plants are not known as a treatment against cancers in North Africa, while 25 plants already known as treatment for cancer were cited here to treat specific new types of this disease.

PMID:34776117 | DOI:10.1016/j.bulcan.2021.09.017

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Translating Access to Outcomes: The Impact of Socioeconomic Status on Completion of Breast Reconstruction at a National Cancer Institute (NCI)-Designated Cancer Center: Impact of SES on Completion

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J Plast Reconstr Aesthet Surg. 2021 Sep 20:S1748-6815(21)00424-1. doi: 10.1016/j.bjps.2021.08.034. Online ahead of print.

ABSTRACT

The purpose of this study was to determine the impact of socioeconomic status (SES) on the completion of breast reconstruction, as defined by the percent of patients undergoing NAC reconstruction. Patients (n=949) who underwent primary breast reconstruction following a mastectomy recorded from 2007 to 2017 were divided into groups based on the median household income of their residential zip code (>/< $67,640). A three-step protocol was designed to (1) broadly compare between patients of low and high SES who were stratified by race and reconstruction type, (2) compare a smaller subset of low SES and high SES patients via propensity matching for demographic, baseline health, and oncologic factors, and (3) elucidate the strongest predictors of non-completion and delayed completion among low SES patients . Patients of lower SES appear less likely to complete NAC reconstruction, especially following staged reconstruction. That this finding presents in staged, but not immediate reconstruction, and disappears with propensity matching for oncologic factors suggests that reduced completion in patients of low SES may be attributable to advanced cancer staging and aggressive adjuvant therapy. Furthermore, expander conversion to autologous reconstruction significantly increased the likelihood of NAC reconstruction in multivariable analysis, and adjuvant radiation therapy significantly increased the time to NAC reconstruction. Further investigation will solidify the relationship between SES, cancer staging, and completion of reconstruction in a multi-site patient population. Larger multivariable analyses may also uncover other factors that can be modified or addressed to increase completion and optimize reconstruction for patients at risk of discontinuation.

PMID:34776390 | DOI:10.1016/j.bjps.2021.08.034

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A supportive donor nerve for long-term facial paralysis: Anatomical analysis of the posterior auricular nerve and micro-anatomical comparison with zygomatic nerve

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J Plast Reconstr Aesthet Surg. 2021 Oct 22:S1748-6815(21)00490-3. doi: 10.1016/j.bjps.2021.09.049. Online ahead of print.

ABSTRACT

BACKGROUND: The posterior auricular nerve (PAN) is an inspiring candidate for the additional axonal source in long-term facial paralysis to improve the functional results of the cross-facial nerve (FN) graft technique. However, no studies have analyzed the PAN's axonal load and its microscopic anatomy to assess its utilization in facial reanimation. The present study aims to examine the anatomical and microscopic features of the PAN to analyze its feasibility as a donor nerve.

METHODS: The bilateral facial side of 14 fresh frozen adult human cadavers was examined for the study. The PAN's anatomical course was recorded, and nerve specimens from the PAN and zygomatic nerve (ZN) were obtained to compare their microscopic anatomy and axon counts using a light microscope and transmission electron microscop e.

RESULTS: The PAN's average branching distance and its course length were 5.8 ± 2.69 mm and 59.2 ± 5.85, respectively. The mean number of myelinated axons was 600.28 ± 69.97 in the PAN and 728.85 ± 166.31 in the ZN. This difference between the two nerves was statistically significant (p = 0.002). However, considering the gender variable, the mean axon counts of PAN and ZN were statistically similar for face sides and their average. Furthermore, the ultrastructural anatomy of both nerves was similar in electron microscopic evaluation.

CONCLUSIONS: The present study confirms that the PAN is a proper candidate to be a supportive donor nerve due to its isolated site, consistent anatomical course, convenient ultrastructural anatomy as well as axonal load.

PMID:34776387 | DOI:10.1016/j.bjps.2021.09.049

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Head and neck research in plastic surgery-Ahead of the rest? An analysis of abstracts presented at British association of plastic reconstructive and aesthetic surgeons meetings

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J Plast Reconstr Aesthet Surg. 2021 Oct 22:S1748-6815(21)00492-7. doi: 10.1016/j.bjps.2021.09.047. Online ahead of print.

ABSTRACT

INTRODUCTION & AIMS: Historically, the head and neck (H&N) discipline has been integral to the service a plastic surgeon provides. Recently, it has been postulated that its popularity is declining. The output of scientific meetings may indicate the popularity of each sub-speciality interest, also allowing comparison with other H&N conferences.

AIM: To analyse the proportion of H&N themed, podium and poster presentations from British Association of Plastic Reconstructive and Aesthetic Surgeons' (BAPRAS) scientific meetings and the resulting contribution to published literature.

MATERIAL AND METHODS: H&N-themed abstracts were identified from finalised programmes of the biannual BAPRAS meetings between 2008 and 2015. PubMed and Google Scholar databases were searched using keywor ds and author names from each abstract to identify subsequent publication in a peer-reviewed journal.

RESULTS: Overall, 19.3% (350/1815) of BAPRAS abstracts were H&N themed. The publication rate of H&N abstracts was 40.3% (141/350), comprising 43.0% (114/265) of podium and 31.8% (27/85) of poster presentations. H&N reconstruction and cleft and craniofacial were the most frequent topics, with facial palsy having the lowest conversion rate at 15.4%. The mean time to publication was 17.8 months. Research was published in 39 journals, with a mean impact factor of 2.151 (range = 0.772-11.541). The most popular journal was Journal of Plastic, Reconstructive & Aesthetic Surgery (JPRAS; 31.7%; 45/141). Published abstracts originated from 17 different countries. The senior author was a plastic surgeon in 77.3% of abstracts.

CONCLUSIONS: From the multiple potential sub-specialties, H&N-themed abstracts consistently contributed 20% of all research presented at B APRAS. The 40.3% publication rate exceeds the international average of scientific meetings. H&N remains a prominent field in the armamentarium of a plastic surgeon.

PMID:34776391 | DOI:10.1016/j.bjps.2021.09.047

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Electrode array design determines scalar position, dislocation rate and angle and postoperative speech perception

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Eur Arch Otorhinolaryngol. 2021 Nov 15. doi: 10.1007/s00405-021-07160-2. Online ahead of print.

ABSTRACT

PURPOSE: The aim of this study is to examine the scalar dislocation rate in straight and perimodiolar electrode arrays in relation to cochlear morphology. Furthermore, we aim to analyze the specific dislocation point of electrode arrays depending on their design and shape and to correlate these results to postoperative speech perception.

METHODS: We conducted a comparative analysis of patients (ears: n = 495) implanted between 2013 and 2018 with inserted perimodiolar or straight electrode arrays from Cochlear™ or MED-EL. CBCT (cone beam computed tomography) was used to determine electrode array position (scalar insertion, intra-cochlear dislocation, point of dislocation and angular insertion depth). Furthermore, cochlear morphology was measured. The postoperative speech discrimination was compared regarding electrode array d islocation, primary scalar insertion and angular insertion depth.

RESULTS: The electrode array with the highest rate of primary SV insertions was the CA; the electrode array with the highest rate of dislocations out of ST was the FlexSoft. We did not find significantly higher dislocation rates in cochleostomy-inserted arrays. The angle of dislocation was electrode array design-specific. A multivariate nonparametric analysis revealed that the dislocation of the electrode array has no significant influence on postoperative speech perception. Nevertheless, increasing angular insertion depth significantly reduced postoperative speech perception for monosyllables.

CONCLUSION: This study demonstrates the significant influence of electrode array design on scalar location, dislocation and the angle of dislocation itself. Straight and perimodiolar electrode arrays differ from each other regarding both the rate and place of dislocation. Insertion via cochleostomy does n ot lead to increased dislocation rates in any of the included electrode arrays. Furthermore, speech perception is significantly negatively influenced by angular insertion depth.

PMID:34778920 | DOI:10.1007/s00405-021-07160-2

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