Monday, August 12, 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


Clinical Otolaryngology Original ArticlesThree‐dimensional computed tomography analysis of frontoethmoidal...
Clinical OtolaryngologyOriginal ArticlesThree‐dimensional computed tomography analysis of frontoethmoidal cells: a critical evaluation of the International Frontal Sinus Anatomy Classification (IFAC)Tomasz Gotlib, Paulina Kołodziejczyk, Magdalena Kuźmińska, Konstancja Bobecka‐Wesołowska, Kazimierz NiemczykFirst Published: 09 August 2019OUR EXPERIENCEA local guideline reduces inappropriate requests for CT imaging of the paranasal sinusesDavid John Laurie Pennell, Emma McClelland, Charlie Sayer, Mahmood...
Αλέξανδρος Γ. Σφακιανάκης
1m
Cutaneous Pathology Accepted Articles Accepted, unedited articles published online and citable. The...
Cutaneous PathologyAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.CASE REPORTSAcantholytic dyskeratosis of the vulva presenting with clinical features of vulval lichen sclerosus‐ a possible rare collision entityDr Ciara Haddadeen, Dr Jeffrey Theaker, Dr David Rowen, Dr Helen LoteryFirst Published: 08 August 2019BRIEF COMMUNICATIONCutaneous Metastases from Prostate Cancer Revealing Neuroendocrine DifferentiationMónica...
Αλέξανδρος Γ. Σφακιανάκης
4m
ORL
1. HAUSSLER SM, Knopke S, Dudka S, Grabel S, et al.[Improvement in tinnitus distress, health-related quality of life and psychological comorbidities by cochlear implantation in single-sided deaf patients. German version]. HNO. 2019 Aug 5. pii: 10.1007/s00106-019-0706-7. doi: 10.1007/s00106-019-0706. PubMed: www.amedeo.com/p2.php?id=31384969&s=orl&pm=2 ABSTRACT available Share: http://m.amedeo.com/313849692. SEGURA-HERNANDEZ M, Valadez-Jimenez VM, Ysunza PA, Sanchez-Valerio AP, et al.Acoustic...
Αλέξανδρος Γ. Σφακιανάκης
4m
A Pharmacogenomic Landscape in Human Liver Cancers Publication date: Available online 1 August 2019...
A Pharmacogenomic Landscape in Human Liver CancersPublication date: Available online 1 August 2019Source: Cancer CellAuthor(s): Zhixin Qiu, Hong Li, Zhengtao Zhang, Zhenfeng Zhu, Sheng He, Xujun Wang, Pengcheng Wang, Jianjie Qin, Liping Zhuang, Wei Wang, Fubo Xie, Ying Gu, Keke Zou, Chao Li, Chun Li, Chenhua Wang, Jin Cen, Xiaotao Chen, Yajing Shu, Zhao ZhangSummaryLiver cancers are highly heterogeneous with poor prognosis and drug response. A better understanding between genetic alterations and...
Αλέξανδρος Γ. Σφακιανάκης
5m
Dermatologic Therapy Early View Online Version of Record before inclusion in an issue THERAPEUTIC HOTLINE:...
Dermatologic Therapy Early View Online Version of Record before inclusion in an issueTHERAPEUTIC HOTLINE: SHORT PAPERSSuccessful treatment of frontal fibrosing alopecia with alitretinoinJi Young Lee, Jong Soo Hong, Seung Ho Lee, Ai‐Young Leee13037 | Version of Record online: 08 August 2019ORIGINAL PAPERSComparison of the efficacy of intralesional bleomycin versus intralesional triamcinolone acetonide in the treatment of keloidsHina A Khan, Mahmood N Sahibzada, Mohammad M Parachae13036 | Version of...
Αλέξανδρος Γ. Σφακιανάκης
5m
Retraction Note to: Diagnostic value of atypical lymphocytes in cerebrospinal fluid from adults with...
Retraction Note to: Diagnostic value of atypical lymphocytes in cerebrospinal fluid from adults with enteroviral meningitisThe Joint Editors-in-Chief have retracted this article [1]. An investigation by Kurume University has not been able to establish what the appropriate authorship should be because one of the authors, Yoshihiro Sato, is now deceased. As the appropriate authorship cannot be determined the Editors-in-Chief no longer have confidence in this article. Kurume University has also stated...
Αλέξανδρος Γ. Σφακιανάκης
6m
Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions: Current and Future Trends...
Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions: Current and Future TrendsChildhood VitiligoAbstractVitiligo is a common acquired depigmenting skin disease characterized by a progressive loss of functional melanocytes. It may appear from the first years of life to late adulthood. Childhood vitiligo (CV), defined as vitiligo that begins before the age of 12 years, is common and may differ from post-CV in terms of epidemiology, clinical presentation, comorbidities, and treatment...
Αλέξανδρος Γ. Σφακιανάκης
7m
Genetic and genomic basis of the mismatch repair system involved in Lynch syndrome In the original...
Genetic and genomic basis of the mismatch repair system involved in Lynch syndromeIn the original publication, part d of Figure 2 was mistakenly not included.Correction to: Real-world treatment of over 1600 Japanese patients with EGFR mutation-positive non-small cell lung cancer with daily afatinibThe original article can be found online.Introduction: Lynch syndrome—its molecular mechanism and current topicsCell-type-specific sensitivity of bortezomib in the methotrexate-resistant primary central...
Αλέξανδρος Γ. Σφακιανάκης
7m
Detection of HPV in oral leukoplakia by brushing and biopsy: prospective study in an Italian cohort...
Detection of HPV in oral leukoplakia by brushing and biopsy: prospective study in an Italian cohortAbstractAimThe aim of the present study was to evaluate the prevalence of HPV infection in oral leukoplakia, specifying the HPV genotypes eventually involved. We also compared the micro-biopsy and brushing HPV detecting efficacy.Materials and methodsConsecutive patients with a presumptive diagnosis of oral leukoplakia were enrolled. Demographical, behavioral data (smoking, alcohol) and lesion features...
Αλέξανδρος Γ. Σφακιανάκης
8m
Impact of a Perioperative Protocol on Length of ICU and Hospital Stay in Complex Spine Surgery Background:...
Impact of a Perioperative Protocol on Length of ICU and Hospital Stay in Complex Spine SurgeryBackground: In an attempt to improve patient care, a perioperative complex spine surgery management protocol was developed through collaboration between spine surgeons and neuroanesthesiologists. The aim of this study was to investigate whether implementation of the protocol in 2015 decreased total hospital and intensive care unit (ICU) length of stay (LOS) and complication rates after elective complex spine...
Αλέξανδρος Γ. Σφακιανάκης
12m
Evaluating Social Complexity and Inequality in the Balkans Between 6500 and 4200 BC Abstract The subject...
Evaluating Social Complexity and Inequality in the Balkans Between 6500 and 4200 BCAbstractThe subject of this paper is the social structure and sociocultural evolution of Balkan Neolithic and Eneolithic societies between 6500 and 4200 BC. I draw on archaeological evidence from three major regions of the Balkans related to demography, settlement, economy, warfare, and differences in status and wealth between individuals and groups to evaluate the degree and kind of social complexity and inequality....
Αλέξανδρος Γ. Σφακιανάκης
12m
 Mission Bio, Onconova Therapeutics Sign Cancer Therapy Research PartnershipPublished on Aug 12, 2019 FDA...
 Mission Bio, Onconova Therapeutics Sign Cancer Therapy Research PartnershipPublished on Aug 12, 2019 FDA Clears Binx Health Point-of-Care Testing Platform for Chlamydia and GonorrheaPublished on Aug 12, 2019 Top Five Articles on GenomeWeb Last Week: Stanford, Guardant Health, Illumina, and MorePublished on Aug 12, 2019Featured in Depth Quidel Updates Dx and MDx Commercial Strategies, PipelinesPublished on Aug 09, 2019 TGen-Led Team Prepares to Validate 'TARDIS' Blood-Based Cancer Monitoring MethodPublished...
Αλέξανδρος Γ. Σφακιανάκης
13m
Fresh osteochondral grafting in the United States: the current status of tissue banking processing Abstract...
Fresh osteochondral grafting in the United States: the current status of tissue banking processingAbstractThe use of musculoskeletal allografts has become increasingly popular among surgeons. The purpose of this review is to highlight the procurment and delievery process of fresh osteochondral allografts in the United States. The four distributors of fresh osteochondral allografts in the United States were contacted. Surveys containing quantitative and qualitative sections concerning the procurement...
Αλέξανδρος Γ. Σφακιανάκης
14m
Nebenwirkung der Sicca-Therapie Forschungs- und Entwicklungsbedarf in der Augenheilkunde („Unmet needs")...
Nebenwirkung der Sicca-TherapieForschungs- und Entwicklungsbedarf in der Augenheilkunde („Unmet needs")ZusammenfassungZielsetzungBestimmung des Forschungs- und Entwicklungsbedarfs, der in den nächsten Jahren (2019–2025) realistischerweise angegangen werden kann, und Beschreibung möglicher Forschungswege, um diesen Herausforderungen zu begegnen.MethodenDie Ergebnisse eines Konsensusprozesses im European Vision Institute (EVI, Brüssel) werden zusammengefasst. Folgende Themengebiete werden behandelt:...
Αλέξανδρος Γ. Σφακιανάκης
14m
Consideration of Anticoagulation: Surgical Care for the Elderly in Current Geriatrics Reports AbstractIntroduction...
Consideration of Anticoagulation: Surgical Care for the Elderly in Current Geriatrics ReportsAbstractIntroductionThe geriatric population in the USA is growing at a dramatic rate. As this segment of the population increases in number, surgical providers will increasingly treat and evaluate patients with age-specific needs that affect surgical or trauma management. Consequently, surgeons should be familiar with trends in prescribing oral anticoagulants (OACs), their association with outcomes, and...
Αλέξανδρος Γ. Σφακιανάκης
15m
Expression Profile and Function Analysis of Long Non-coding RNAs in the Infection of Coxsackievirus...
Expression Profile and Function Analysis of Long Non-coding RNAs in the Infection of Coxsackievirus B3AbstractThe roles of lncRNAs in the infection of enteroviruses have been barely demonstrated. In this study, we used coxsackievirus B3 (CVB3), a typical enterovirus, as a model to investigate the expression profiles and functional roles of lncRNAs in enterovirus infection. We profiled lncRNAs and mRNA expression in CVB3-infected HeLa cells by lncRNA-mRNA integrated microarrays. As a result, 700 differentially...
Αλέξανδρος Γ. Σφακιανάκης
15m
Alcohol Medical Intervention Clinic: A Rapid Access Addiction Medicine Model Reduces Emergency Department...
Alcohol Medical Intervention Clinic: A Rapid Access Addiction Medicine Model Reduces Emergency Department VisitsObjectives: Problematic alcohol use accounts for a large proportion of Emergency Department (ED) visits and revisits. We developed the Alcohol Medical Intervention Clinic (AMIC), a Rapid Access Addiction Medicine (RAAM) service, to reduce alcohol-related ED re-utilization and improve care for individuals with alcohol problems. This article describes the AMIC model and reports on an evaluation...
Αλέξανδρος Γ. Σφακιανάκης
16m
NanoString Spatial Profiler Users Share New Data as Company Reports Flourishing Early InterestPublished...
NanoString Spatial Profiler Users Share New Data as Company Reports Flourishing Early InterestPublished on Aug 02, 2019Anorexia GWAS Yields Risk Loci with Metabolic, Psychiatric OverlapPublished on Jul 15, 2019
Αλέξανδρος Γ. Σφακιανάκης
16m
TcMYB1 , TcMYB4 , and TcMYB8 participate in the regulation of lignan biosynthesis in Taiwania cryptomerioides...
TcMYB1 , TcMYB4 , and TcMYB8 participate in the regulation of lignan biosynthesis in Taiwania cryptomerioides HayataAbstractTaiwania (Taiwania cryptomerioides Hayata) is a conifer species that is rich in bioactive secondary metabolites. Lignans, which are the major extracts, are especially important, but the biosynthetic gene regulation and downstream biosynthesis pathways remain unclear. In a previous study, we identified three pinoresinol-lariciresinol reductase (PLR) genes in Taiwanina, and in...
Αλέξανδρος Γ. Σφακιανάκης
17m
Sex-Specific Differences in Ventricular Dimensions in Repaired Tetralogy of Fallot: A Retrospective...
Sex-Specific Differences in Ventricular Dimensions in Repaired Tetralogy of Fallot: A Retrospective StudyAbstractThe timing of pulmonary valve replacement (PVR) in asymptomatic patients with repaired tetralogy of Fallot (TOF) is typically based on cardiac magnetic resonance imaging-derived ventricular volume measurements. Current criteria do not account for sex-based differences in chamber size. The purpose of this study was to compare male and female ventricular volumes and function in TOF patients...
Αλέξανδρος Γ. Σφακιανάκης
17m
Algicoccus marinus gen. nov. sp. nov., a marine bacterium isolated from the surface of brown seaweed...
Algicoccus marinus gen. nov. sp. nov., a marine bacterium isolated from the surface of brown seaweed Laminaria japonicaAbstractA Gram-staining-negative, strictly aerobic, non-motile, ovoid- to rod-shaped bacterium, designated as HZ20T, was isolated from the surface of a brown seaweed (Laminaria japonica) sample collected from the East China Sea. Colonies are 1.0–2.0 mm in diameter, smooth, circular, convex and yellow after grown on MA at 28 °C for 72 h. The strain was found to grow at 4–50 °C (optimum,...
Αλέξανδρος Γ. Σφακιανάκης
18m
Nichtdeutsche Staatsbürger im Maßregelvollzug gemäß § 64 StGB – Jahres- und Bundesländervergleich der...
Nichtdeutsche Staatsbürger im Maßregelvollzug gemäß § 64 StGB – Jahres- und Bundesländervergleich der Neuanordnungen 2010–2015 sowie GruppenbesonderheitenErratum zu:Forens Psychiatr Psychol Kriminol 2019https://doi.org/10.1007/s11757-019-00526-7Leider hat sich in der Originalpublikation bei der Beschriftung von Abb. 3 der Fehlerteufel eingeschlichen: Entgegen der Angabe handelt es sich ausschließlich um Neuanordnungen gemäß § 64 StGB. Wir bitten, …Kongresskalender Heft 3/19Psychiatrischer BeitragSublime...
Αλέξανδρος Γ. Σφακιανάκης
19m
Development of positional obstructive sleep apnea (POSA) after upper airway surgery in OSA patients
Abstract Purpose Positional therapy (PT) has become more reliable for obstructive sleep apnea (OSA) patients with the use of new devices. The objectives of this study were to determine the preoperative prevalence of positional OSA (POSA) in our population of surgically treated patients and the proportion of patients who developed POSA after surgery and might improve with additional positional therapy. ...
Latest Results for Sleep and Breathing
20m
RESEARCH HIGHLIGHTS Settling down on chitin  Andrea Du Toit p527 | doi:10.1038/s41579-019-0237-y Two...
RESEARCH HIGHLIGHTS Settling down on chitin Andrea Du Toit p527 | doi:10.1038/s41579-019-0237-y Two papers provide novel insights into how Vibrio cholerae colonizes chitin, revealing the role of a type IV pilus and filamentation. PDF Phospholipid export from the inside out Andrea Du Toit p528 | doi:10.1038/s41579-019-0239-9 The results of this study suggest that the Mla pathway may be involved in anterograde phospholipid transport to the bacterial outer membrane. PDF Jumping from well to well Andrea...
Αλέξανδρος Γ. Σφακιανάκης
20m
DAO
Poo, Mu-Chou, H. A. Drake, and Lisa Raphals, eds., Old Society, New Belief: Religious Transformation of China and Rome, ca. 1st–6th CenturiesResponse to Jim BehuniakGao, Ruiquan 高瑞泉, A General Discourse on the History of Ideas of Equality 平等觀念史論略Behuniak, Jim, ed., Appreciating the Chinese Difference: Engaging Roger T. Ames on Methods, Issues, and RolesResponse to Edward SlingerlandGuo, Qiyong 郭齊勇, Investigations of Contemporary Neo-Confucian Thoughts 現當代新儒學思潮研究Yuan, Cheng, Practical Intellect and...
Αλέξανδρος Γ. Σφακιανάκης
25m
The clinical appearance of fuso-spirillar infection in patients with a serious impairment of the immunitary system was the starting-point for a historical study. At the end of nineteenth century two european researchers clarified the cause of many infections. Association of a spindle-shaped bacillus with a spirillar one was shown to cause several pathologies: necrotic ulcerous stomatitis, pseudomembranous angina, hepatic abscess, otitis, pneumonia, etc. The identification of such bacteria contributed to improving further differential diagnosis with diphteria.
Acute necrotizing ulcerative gingivitis (ANUG) is a common, non-contagious infection of the gums with sudden onset. The main features are painful, bleeding gums, and ulceration of inter-dental papillae (the sections of gum between adjacent teeth).This disease, along with necrotizing (ulcerative) periodontitis (NP or NUP) is classified as a necrotizing periodontal disease, one of the seven general types of gum disease caused by inflammation of the gums (periodontitis). The often severe gum pain that...
Αλέξανδρος Γ. Σφακιανάκης
26m
Outcomes of Cadaveric Allograft versus Autologous Cartilage Graft in Functional Septorhinoplasty Show...
Outcomes of Cadaveric Allograft versus Autologous Cartilage Graft in Functional SeptorhinoplastyShow lessRobert Saadi, MD, Justin Loloi, MS, Eric Schaefer, MS, Jessyka G. Lighthall, MD First Published August 6, 2019 Research Article https://doi.org/10.1177/0194599819866812Article information  No AccessAbstractObjectiveOur goal was to elucidate the efficacy and outcome profile of cadaveric allografts (homograft costal cartilage) in functional septorhinoplasty as compared with autografts (quadrangular...
Αλέξανδρος Γ. Σφακιανάκης
30m
Factors Associated with Free Flap Failures in Head and Neck Reconstruction Show less Meghan B. Crawley,...
Factors Associated with Free Flap Failures in Head and Neck ReconstructionShow lessMeghan B. Crawley, MD, Larissa Sweeny, MD, Prasanti Ravipati, Ryan Heffelfinger, MD, Howard Krein, MD, Adam Luginbuhl, MD, Richard Goldman, MD, Joseph Curry, MD First Published August 6, 2019 Research Article https://doi.org/10.1177/0194599819860809Article information  No AccessAbstractObjectiveTo investigate causes of failure of free flap reconstructions in patients undergoing reconstruction of head and neck defects.Study...
Αλέξανδρος Γ. Σφακιανάκης
30m
The Potential of High-Throughput DNA Sequencing of the Paranasal Sinus Microbiome in Diagnosing Odontogenic...
The Potential of High-Throughput DNA Sequencing of the Paranasal Sinus Microbiome in Diagnosing Odontogenic SinusitisShow lessAsad A. Haider, Michael J. Marino, MD, William C. Yao, MD, Martin J. Citardi, MD, Amber U. Luong, MD, PhD First Published August 6, 2019 Research Article https://doi.org/10.1177/0194599819866692Article information Article has an altmetric score of 1   No AccessAbstractObjectiveHigh-throughput DNA sequencing of the paranasal sinus microbiome has potential in the diagnosis and...
Αλέξανδρος Γ. Σφακιανάκης
31m
Association of Midlife Hypertension with Late-Life Hearing Loss Show less Nicholas S. Reed, AuD, Matthew...
Association of Midlife Hypertension with Late-Life Hearing LossShow lessNicholas S. Reed, AuD, Matthew G. Huddle, MD, Joshua Betz, MS, Melinda C. Power, ScD, James S. Pankow, PhD, MPH, Rebecca Gottesman, MD, PhD, A. Richey Sharrett, MD, Thomas H. Mosley, PhD, Frank R. Lin, MD, PhD, Jennifer A. Deal, PhD First Published August 6, 2019 Research Article https://doi.org/10.1177/0194599819868145Article information  No AccessAbstractObjectiveTo investigate the association of midlife hypertension with late-life...
Αλέξανδρος Γ. Σφακιανάκης
31m
Investigation of Genetic Diversity in Apple Scab ( Venturia inaequalis ) Isolated from Two Different...
Investigation of Genetic Diversity in Apple Scab ( Venturia inaequalis ) Isolated from Two Different Geographical Areas of TurkeyAbstractApple (Malus domestica) is a widely grown fruit in various climate types of the world and is exposed to the attack of many fungal disease agents during the growing period. One of them is Venturia inaequalis, which is probably the most important in terms of economic loss worldwide, which makes apple scab disease important in apple growing areas. In this study, the...
Αλέξανδρος Γ. Σφακιανάκης
32m
Otolaryngology–Head and Neck Surgery are available onlineView online OnlineFirst Alert Clinical PhotographPlaut-Vincent's...
Otolaryngology–Head and Neck Surgery are available onlineView onlineOnlineFirst AlertClinical PhotographPlaut-Vincent's Ulcerative Gingivitis and TonsillitisFrancesco Maccarrone, Matteo Alicandri-CiufelliOtolaryngology–Head and Neck SurgeryAug 6, 2019 | OnlineFirstOriginal ResearchOutcomes of Cadaveric Allograft versus Autologous Cartilage Graft in Functional SeptorhinoplastyRobert Saadi, Justin Loloi, Eric Schaefer, Jessyka G. LighthallOtolaryngology–Head and Neck SurgeryAug 6, 2019 | OnlineFirstOriginal...
Αλέξανδρος Γ. Σφακιανάκης
33m
 Allergy  An update to the Milk Allergy in Primary Care guideline The Milk Allergy in Primary...
 Allergy An update to the Milk Allergy in Primary Care guidelineThe Milk Allergy in Primary (MAP) Care guideline was first published in 2013 in this journal. MAP aimed to provide simple and accessible algorithms for UK clinicians in primary care, detailing all the steps be...Allergy1mMark above section as read pubmed: sleep apneaThe impact of oral appliance therapy with moderate mandibular advancement on obstructive sleep apnea and upper airway volume.Related ArticlesThe impact of oral appliance...
Αλέξανδρος Γ. Σφακιανάκης
35m
Demographic history, linked selection, and recombination shape the genomic landscape of a broadly distributed Pacific salmon. [NEW RESULTS]
Understanding the impacts of current human activities on within-species genetic variation requires a thorough description of the historical factors that have shaped the genomic and geographical distribution of nucleotide diversity. Past and current conditions influencing effective population size have important evolutionary implications for the efficacy of selection, increased accumulation of deleterious mutations, and loss of adaptive potential under the nearly neutral theory. Here, we gather extensive...
bioRxiv Subject Collection: Evolutionary Biology
36m
 Anthropology-News  Building a Diverse and Inclusive Archaeology Most of us who discovered our...
 Anthropology-News Building a Diverse and Inclusive ArchaeologyMost of us who discovered our passion for archaeology as children were white and middle-class. When my mother was a child, my grandmother worried that no one would never marry her because she had too many opinions. My mother decided she didn't need a husband anyway, and that she would someday adopt a daughter and name her Laura, after the similarly-opinionated heroine of her favorite books: the Little House series by Laura Ingalls Wilder....
Αλέξανδρος Γ. Σφακιανάκης
37m
 BMC Research Notes  Adverse events with fatal outcome associated with alemtuzumab treatment in...
 BMC Research Notes Adverse events with fatal outcome associated with alemtuzumab treatment in multiple sclerosisSporadic fatal adverse events have been reported during treatment of multiple sclerosis with alemtuzumab. To provide a systematic overview, we searched the centralized European Medicines Agency database of sus...BMC Research Notes7hMark above section as read Annals of Internal Medicine Online FirstGeneral and Abdominal Adiposity and Mortality in Mexico City Prospective Study of 150 000...
Αλέξανδρος Γ. Σφακιανάκης
39m
An update to the Milk Allergy in Primary Care guideline
The Milk Allergy in Primary (MAP) Care guideline was first published in 2013 in this journal. MAP aimed to provide simple and accessible algorithms for UK clinicians in primary care, detailing all the steps be...
Allergy
39m

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