A 44 minute video that manages to capture all my own reasons for not liking Object Oriented Programming plus precisely laying out a bunch more I vaguely felt; but done in a clear way. Continue reading →
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By Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete,Greece,00302841026182,00306932607174
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Wednesday, December 26, 2018
Why Object Oriented Programming Is Bad
EU Migration Pact Crisis
A 10+ minuted video on Europe and their dislike of the Globalist / Migration Agenda. Continue reading →
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Shell Announces Major Pivot To Green Energy
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Metaplastic carcinoma of breast
: A series of nine cases from a regional cancer center in Northeast India | p. 69 |
Srigopal Mohanty, Yumkhaibam Sobita Devi, Daffilyne Lyngdoh Nongrum, Laishram Jaichand Singh, Vimal Sekar, Deep Sikha Das DOI:10.4103/oji.oji_39_18 Background: Metaplastic carcinoma of the breast (MCB) is a rare histological subtype of breast carcinoma containing glandular and nonglandular components with mixed epithelial and mesenchymal differentiations. Aim of the Study: The study aimed to report clinical, radiological and pathological profiles, treatment and outcome of patients diagnosed with MCB from a tertiary care institute along with literature review. Materials and Methods:Diagnosed cases of MCB were obtained from the record over a period of January 2010 to December 2017, and data were recorded in a structured pro forma. Results: A total of 9 (0.9%) cases of MCB were identified out of 1031 breast cancer patients with the median age of presentation of 53 years. The palpable lump was the most common presentation (77.78%). The mean tumor size was 4.9 cm in greatest dimension. Sonographically, most of the lesions were solid (44.44%) followed by cystic (33.33%). Mammographically, microcalcifications were absent in eight cases. Histologically, 55.56% of cases were purely epithelial subtype (3: pure squamous and 2: adenosquamous) and 4 (44.44%) cases were mixed epithelial and mesenchymal subtypes (3: carcinosarcoma and 1: invasive lobular carcinoma with sarcomatous component and osseous metaplasia). All the cases were having triple-negative receptor status. Modified radical mastectomy (MRM) was performed in all cases and 33.33% of cases had axillary node positive. About 77.88% and 88.89% of cases received adjuvant chemotherapy and adjuvant radiotherapy, respectively. At median follow-up of 27 months, local recurrence and distant metastases were seen in 1 and 3 cases, respectively. At present, 33.33%, 22.22%, and 44.45% of patients were died, alive, and lost for follow-up, respectively. Conclusion: MCB is a rare histologic subtype of breast cancer with larger tumor size at presentation and MRM is the preferred surgical procedure over breast conservation surgery. Long-term and regular follow-up is necessary to know the outcome. |
Anti-cancer and anti-inflammatory activities of aronia (Aronia melanocarpa) leaves
Effects of phototherapy on outer hair cell function in infants with hyperbilirubinemia
Vikas Mysore Dwarakanath, Pavana Mohan, Sapthami Patel
DOI:10.4103/jisha.JISHA_8_17
Introduction: Hyperbilirubinemia in newborns has been hypothesized to cause damage to inner ear, thus leading to sensorineural hearing loss. Phototherapy is treatment protocol in most of the hospitals for newborns with high bilirubin levels. The present study aimed to determine the effects of phototherapy on outer hair cell (OHC) function of cochlea. Methods: Twenty-two neonates with hyperbilirubinemia undergoing phototherapy and 22 neonates without any high-risk registers were included in the study. Distortion product otoacoustic emission (DPOAE) was administered before and after phototherapy. Auditory brainstem response (ABR) evaluation was done during the postphototherapy recording. Results: Results showed that DP amplitude and signal-to-noise ratio improved significantly after phototherapy. ABR evaluation revealed; 19 neonates had significantly prolonged wave V latency compared to normal, whereas no peaks were identified among three neonates. Most of the infantile hyperbilirubinemia are found to be harmless until and unless treatment is not initiated at the earliest, but still it is found that short-term increase in bilirubin level can induce temporary changes in OAEs and ABR measures. ABR needs to be repeated over a period of time for these three neonates to rule out auditory dyssynchrony (AD). Conclusion: The results indicate that phototherapy has temporary effects on OHC function and can improve as the bilirubin levels reduce. Follow-up testing over a period of time helps in discriminating the sensory pathology and AD.
http://www.jisha.org/currentissue.asp?sabs=y
Long-term exposure to traffic noise
PG Vipin Ghosh, D Nagashreeya, V Hemavathi
DOI:10.4103/jisha.JISHA_24_18
Introduction: The acceptable noise level (ANL) measure is a subjective way of identifying how much of noise a person is able to put up with while listening to speech. Individuals with low ANL were observed to be satisfied hearing users than the individuals with high ANL. However, the reason for large individual variations of the measure is still not well understood. Exposure to noise may be one such factor that would affect the ANL which was never explored. Among the individuals who are exposed to noise, majority are exposed to occupational noise. Traffic police is such a working population who is exposed continuously to traffic noise during their duty hours. Hence, the present study was planned to investigate ANL measures in traffic police officers that might further provide insight toward the heterogeneity of the measure. Methods: A total of 38 participants were divided into two groups. Group 1 consisted of 19 traffic police officers with minimum of 5 years of job experience and Group 2 consisted of normal hearing individuals without any noise exposure. All the participants underwent routine audiological evaluations followed by ANL testing. Results: The mean ANL obtained in both the groups was statistically compared. The results revealed that the traffic police officers yielded better ANLs than participants in Group 2. Conclusion: This ability of traffic police officers to put up with more noise while listening to speech may be attributed to their long-standing experience in listening to wanted signals in noise.
http://www.jisha.org/currentissue.asp?sabs=y
“Slime” dermatitis, a fad‐associated chronic hand dermatitis - Kondratuk - - Pediatric Dermatology - Wiley Online Library
https://onlinelibrary.wiley.com/doi/10.1111/pde.13729
The impact of pediatric atopic dermatitis on families: A review - Yang - - Pediatric Dermatology - Wiley Online Library
Objective
This literature review outlines how atopic dermatitis impacts the quality of life of families of children affected by AD.
Methods
A total of 3436 articles were identified via an online search of the MEDLINE health literature database and were screened for relevance to quality of life impacts on families with children affected by AD.
Results
Caring for children affected by AD can be an extremely time‐consuming task that can impair personal relationships, decrease psychosocial functioning, and cause sleep loss among family members of affected patients. Additionally, AD may result in work absence or decreased work productivity for caregivers. Special diets, irritant and allergen avoidance strategies, and alternative therapies are commonly used by patients to manage their disease and require large amounts of family involvement.
Conclusions
Atopic dermatitis can greatly decrease quality of life of families of affected children in various domains, including sleep, finances, and relationships. Early intervention and psychotherapy may be needed in some patients to address these quality of life impairments.
https://onlinelibrary.wiley.com/doi/10.1111/pde.13727
Successful treatment of hemorrhagic bullous Henoch‐Schonlein purpura with intravenous immunoglobulins - Mauro - - Pediatric Dermatology - Wiley Online Library
https://onlinelibrary.wiley.com/doi/10.1111/pde.13715
Biology of human melanocyte development, Piebaldism, and Waardenburg syndrome - Saleem - - Pediatric Dermatology - Wiley Online Library
https://onlinelibrary.wiley.com/doi/10.1111/pde.13713
Focal facial dermal dysplasia type 4.Bilateral preauricular scarlike defects surrounded by a hair collar, resembling membranous aplasia cutis congenita.
https://onlinelibrary.wiley.com/doi/10.1111/pde.13730
Bullous pemphigoid in adolescence - Patsatsi - - Pediatric Dermatology - Wiley Online Library
https://onlinelibrary.wiley.com/doi/10.1111/pde.13717
Claim: Climate Conscious Tesla Owners being harassed by ICE Drivers
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2018 sees record low death toll & no violent (EF4 or EF5) tornadoes for first time since records began in 1950
https://wapo.st/2BFqZK9 In the whirlwind that is 2018, there has been a notable lack of high-end twisters. We're now days away from this becoming the first year in the modern record with no violent tornadoes touching down in the United States. Violent tornadoes are the strongest on a 0 to 5 scale, or those ranked EF4 or [...]
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NBC News: ‘Dire climate reports’ intensifying mental health effects of ‘global warming’ – ‘Climate grief’ – Kids in tears after UN IPCC report
https://nbcnews.to/2BBctD1 By Avichai Scher When the U.N. released its latest climate report in October, it warned that without "unprecedented" action, catastrophic conditions could arrive by 2040. For Amy Jordan, 40, of Salt Lake City, a mother of three teenage children, the report caused a "crisis." "The emotional reaction of my kids was severe," she told [...]
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European wheat lacks climate resilience
From EurekAlert! Public Release: 26-Dec-2018 European wheat lacks climate resilience European farmers need to take a new course with regard to ensuring climate-resilience of important crops such as wheat Aarhus University The climate is not only warming, it is also becoming more variable and extreme. Such unpredictable weather can weaken global food security if major…
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Another day, another feeble climate scare story
Brace for impact: 'Hotter days will boost Chinese residential electric use'. Are we supposed to weep instead of sleep? The report refers to 'China's low-carbon policy', which must be something other than the one which sees it opening a new coal-fired power station almost every week, and which led to a massive long-term import contract with Russia for natural gas. Who are they kidding?
A new study from Duke University and Fudan University in China is the first to estimate how much Chinese residential electricity consumption would increase due to climate change.
It's a lot, says Phys.org.
By the end of the 21st century, each degree Celsius increase in global mean surface temperature (GMST) would raise average Chinese residential electricity use by about 9 percent.
Peak electricity use will rise 36 percent for every increased degree Celsius.
By 2099, scientists estimate mean surface temperature will be 2-5 C hotter than today. If consumption patterns remained similar to today, average residential electricity demand in China would rise by 18 percent at the low end and as much as 55 percent at the high end. Peak usage would rise by a minimum of 72 percent.
This finding has important implications for energy grid planning, but even without climate change, average household electricity consumption in China is projected to double by 2040 due to rising incomes.
The study, "Climate Change and Residential Electricity Consumption in the Yangtze River Delta, China," by Yating Li, William A. Pizer, and Libo Wu, appears the week of December 24 in the Proceedings of the National Academy of Sciences.
"Our findings contribute solid evidence supporting China's low-carbon policy by showing how important increasing demand from the residential sector will be," said Libo Wu, a professor and director of the Center for Energy Economics and Strategies Studies at Fudan.
To examine how customers responded to daily temperature changes, the authors analyzed data from more than 800,000 residential customers in the Pudong district of Shanghai between 2014 and 2016.
They combined these data on consumer behavior with a variety of detailed climate model simulations to construct the relationship between projected mean global temperature change at the end of the century and localized projected impacts in China.
"This state-of-the-art approach has been applied to communities in the United States, but this is the first application in China," said Billy Pizer, a professor in Duke's Sanford School of Public Policy and Duke Kunshan University in Jiangsu Province, China.
Most previous studies of these impacts have been done in Western countries.
Continued here.
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[ASAP] Bismuth Enhances the Stability of CH3NH3PbI3 (MAPI) Perovskite under High Humidity
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[ASAP] One-Step Nanoscale Patterning of Silver Nanowire–Nitride Heterostructures Using Substrate-Assisted Chemical Etching
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[ASAP] Investigation of the Dynamics of 1-Octene Adsorption at 293 K in a ZSM-5 Catalyst by Inelastic and Quasielastic Neutron Scattering
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[ASAP] Anion-dependent Hot Carrier Dynamics in Chalcogenide Perovskites SrSnX3 (X = S, Se)
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[ASAP] Self-Assembly of Oligo(phenylene-thiophene)s on Monolayer Graphene: Molecular Dynamics Simulations
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[ASAP] Insights into the Efficient Intersystem Crossing of Bodipy-Anthracene Compact Dyads with Steady-State and Time-Resolved Optical/Magnetic Spectroscopies and Observation of the Delayed Fluorescence
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[ASAP] Detecting DNA Methylation Using Surface-Enhanced Raman Spectroscopy
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[ASAP] Assembly of Zeolitic Crystals From a Model of Mesogenic Patchy Nanoparticles
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[ASAP] Unconventional Long-Range Cation Ordering in Copper Selenide Nanocrystals
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[ASAP] Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis
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[ASAP] Transition of Metastable Cross-a Crystals into Cross-ß Fibrils by ß-Turn Flipping
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[ASAP] High Hole Mobility and Nonsaturating Giant Magnetoresistance in the New 2D Metal NaCu4Se4 Synthesized by a Unique Pathway
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[ASAP] A Dynamic Tetracationic Macrocycle Exhibiting Photoswitchable Molecular Encapsulation
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[ASAP] Solution Processing for Lateral Transition-Metal Dichalcogenides Homojunction from Polymorphic Crystal
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This is the fourth in a series of posts based upon Jordan Peterson's book Maps of Meaning, published in 1999 after 17 years of researc...