Cells, Vol. 8, Pages 1372: Wnt-3a Induces Cytokine Release in Human Mast CellsCells, Vol. 8, Pages 1372: Wnt-3a Induces Cytokine Release in Human Mast Cells Cells doi: 10.3390/cells8111372 Authors: Julia Tebroke Joris E. Lieverse Jesper Säfholm Gunnar Schulte Gunnar Nilsson Elin Rönnberg Mast cells are well known for their detrimental effects in allergies and asthma, and Wnt signaling has recently been implicated in asthma and other airway diseases. However, it is not known if or how Wnts affect...
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Sensors, Vol. 19, Pages 4733: An Identity Authentication Method Combining Liveness Detection and Face RecognitionSensors, Vol. 19, Pages 4733: An Identity Authentication Method Combining Liveness Detection and Face Recognition Sensors doi: 10.3390/s19214733 Authors: Shuhua Liu Yu Song Mengyu Zhang Jianwei Zhao Shihao Yang Kun Hou In this study, an advanced Kinect sensor was adopted to acquire infrared radiation (IR) images for liveness detection. The proposed liveness detection method based on infrared...
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Water, Vol. 11, Pages 2281: Mathematical Reconstruction of Eroded Beach Ridges at the Ombrone River DeltaWater, Vol. 11, Pages 2281: Mathematical Reconstruction of Eroded Beach Ridges at the Ombrone River Delta Water doi: 10.3390/w11112281 Authors: Irene Mammì Lorenzo Rossi Enzo Pranzini Several remotely sensed images, acquired by different sensors on satellite, airplane, and drone, were used to trace the beach ridges pattern present on the delta of the River Ombrone. A more detailed map of these...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 16, Pages 4244: Daily Physical Activity Among Toddlers: Hip and Wrist Accelerometer AssessmentsIJERPH, Vol. 16, Pages 4244: Daily Physical Activity Among Toddlers: Hip and Wrist Accelerometer Assessments International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214244 Authors: Soyang Kwon Kyle Honegger Maryann Mason Physical activity (PA) habits seem to track over time from as young as early...
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Viruses, Vol. 11, Pages 1009: The C4 Protein from Tomato Yellow Leaf Curl Virus Can Broadly Interact with Plant Receptor-Like KinasesViruses, Vol. 11, Pages 1009: The C4 Protein from Tomato Yellow Leaf Curl Virus Can Broadly Interact with Plant Receptor-Like Kinases Viruses doi: 10.3390/v11111009 Authors: Borja Garnelo Gómez Dan Zhang Tábata Rosas-Díaz Yali Wei Alberto P. Macho Rosa Lozano-Durán Plant receptor-like kinases (RLKs) exert an essential function in the transduction of signals from the...
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Pharmaceutics, Vol. 11, Pages 566: Population Pharmacokinetics Modelling and Simulation of Mitotane in Patients with Adrenocortical Carcinoma: An Individualized Dose Regimen to Target All Patients at Three Months?Pharmaceutics, Vol. 11, Pages 566: Population Pharmacokinetics Modelling and Simulation of Mitotane in Patients with Adrenocortical Carcinoma: An Individualized Dose Regimen to Target All Patients at Three Months? Pharmaceutics doi: 10.3390/pharmaceutics11110566 Authors: Yoann Cazaubon Yohann...
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Molecules, Vol. 24, Pages 3946: Protective Effect and Mechanism of Boswellic Acid and Myrrha Sesquiterpenes with Different Proportions of Compatibility on Neuroinflammation by LPS-Induced BV2 Cells Combined with Network PharmacologyMolecules, Vol. 24, Pages 3946: Protective Effect and Mechanism of Boswellic Acid and Myrrha Sesquiterpenes with Different Proportions of Compatibility on Neuroinflammation by LPS-Induced BV2 Cells Combined with Network Pharmacology Molecules doi: 10.3390/molecules24213946...
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IJMS, Vol. 20, Pages 5445: Transcription Factors Targeted by miRNAs Regulating Smooth Muscle Cell...
IJMS, Vol. 20, Pages 5445: Transcription Factors Targeted by miRNAs Regulating Smooth Muscle Cell Growth and Intimal Thickening after Vascular InjuryIJMS, Vol. 20, Pages 5445: Transcription Factors Targeted by miRNAs Regulating Smooth Muscle Cell Growth and Intimal Thickening after Vascular Injury International Journal of Molecular Sciences doi: 10.3390/ijms20215445 Authors: Khachigian Neointima formation after percutaneous coronary intervention (PCI) is a manifestation of "phenotype switching" by...
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Cells, Vol. 8, Pages 1368: Mitotic Chromosomes in Live Cells Characterized Using High-Speed and Label-Free Optical Diffraction TomographyCells, Vol. 8, Pages 1368: Mitotic Chromosomes in Live Cells Characterized Using High-Speed and Label-Free Optical Diffraction Tomography Cells doi: 10.3390/cells8111368 Authors: Kim Lee Fujii Lee Lee Park Kim Lee Pack The cell nucleus is a three-dimensional, dynamic organelle organized into subnuclear compartments such as chromatin and nucleoli. The structure and...
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Applied Sciences, Vol. 9, Pages 4650: A Gene Expression Programming Model for Predicting Tunnel ConvergenceApplied Sciences, Vol. 9, Pages 4650: A Gene Expression Programming Model for Predicting Tunnel Convergence Applied Sciences doi: 10.3390/app9214650 Authors: Mohsen Hajihassani Shahrum Shah Abdullah Panagiotis G. Asteris Danial Jahed Armaghani Underground spaces have become increasingly important in recent decades in metropolises. In this regard, the demand for the use of underground spaces...
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MDPI PublishingC, Vol. 5, Pages 67: Two-Dimensional Carbon: A Review of Synthesis Methods, and Electronic, Optical, and Vibrational Properties of Single-Layer GrapheneC, Vol. 5, Pages 67: Two-Dimensional Carbon: A Review of Synthesis Methods, and Electronic, Optical, and Vibrational Properties of Single-Layer Graphene C — Journal of Carbon Research doi: 10.3390/c5040067 Authors: Angelo Armano Simonpietro Agnello Graphite has been widely used by humans for a large part of their history. Nevertheless,...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 16, Pages 4241: Greening Blocks: A Conceptual Typology of Practical Design Interventions to Integrate Health and Climate Resilience Co-BenefitsIJERPH, Vol. 16, Pages 4241: Greening Blocks: A Conceptual Typology of Practical Design Interventions to Integrate Health and Climate Resilience Co-Benefits International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214241 Authors: Sara Barron Sophie...
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Black and elderly patients less likely to receive lung cancer treatments(American Thoracic Society) Only about 6 in 10 lung cancer patients in the United States receive the minimal lung cancer treatments recommended by the National Comprehensive Cancer Network guidelines, according to new research published online in the Annals of the American Thoracic Society.EurekAlert! - Medicine and Health06:00Science snapshots from Berkeley Lab(DOE/Lawrence Berkeley National Laboratory) New at Berkeley Lab:...
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Κλινική Αξιολόγηση και ΣυμβουλευτικήOι εκδόσεις Π. Ασημάκη σας προσκαλούν στην παρουσίαση του βιβλίου των Μ. Κολέτση και Ε. Τράγου "Κλινική Αξιολόγηση & Συμβουλευτική" την Τετάρτη 6 Νοεμβρίου στις 18.00 στο Polis Art Café (Ι. Πεσματζόγλου 5, Αίθριο Στοάς του Βιβλίου)E-Psychology.gr - Ψυχολογία, Άρθρα ψυχολογίας, Ψυχική Υγεία, ψυχοθεραπεία, συμβουλευτικήThu Oct 31, 2019 11:28Παίρνεις συνεχώς βάρος στην κοιλιά; 3 σημάδια που αποδεικνύουν πως δεν φταίει το φαγητόΣταμάτα να κατηγορείς για όλα το...
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Autofluorescence Imaging to Monitor the Progression of Oral Potentially Malignant DisordersPatients with oral potentially malignant disorders (OPMD) must undergo regular clinical surveillance to ensure that any progression to malignancy is detected promptly. Autofluorescence imaging (AFI) is an optical modality that can assist clinicians in detecting early cancers and high-grade dysplasia. Patients with OPMD undergoing surveillance for the development of oral cancer were examined using AFI at successive...
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BMP-3 Promotes Matrix Production in Co-cultured Stem Cells and Disc Cells from Low Back Pain PatientsTissue Engineering Part A, Ahead of Print.Tissue Engineering Part A - Table of ContentsThu Oct 31, 2019 09:00Identification of driver genes regulating immune cell infiltration in cervical cancer by multiple omics integrationPublication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Yanqi Wen, Silin Zhang, Jing Yang, Duanying GuoAbstractCervical cancer (CC) is one...
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Does Geographical Bias Impact the Match for General Surgery Residents?Publication date: Available online 31 October 2019Source: Journal of Surgical EducationAuthor(s): Vikrom K. Dhar, Dennis J. Hanseman, Gilda Young, Deborah Browne, Amy T. Makley, Jeffrey J. Sussman, Michael D. GoodmanOBJECTIVEAs the competitiveness of applicants for general surgery residency grows, it is becoming challenging for programs to differentiate qualified candidates with a genuine interest in matching at their institution....
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Luteolin Alters Macrophage Polarization to Inhibit InflammationAbstract Luteolin is a natural flavonoid compound derived from vegetables, fruits, and herbs with potent anti-inflammatory activity. Macrophage polarization is important in the development and progression of inflammation. However, whether luteolin can inhibit inflammation by regulating the polarized phenotypes of macrophages remains unknown. The aim of this study was to investigate the effects of luteolin on the inflammatory polarization...Latest...
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Clonal hematopoiesis in human aging and diseaseAs people age, their tissues accumulate an increasing number of somatic mutations. Although most of these mutations are of little or no functional consequence, a mutation may arise that confers a fitness advantage on a cell. When this process happens in the hematopoietic system, a substantial proportion of circulating blood cells may derive from a single mutated stem cell. This outgrowth, called "clonal hematopoiesis," is highly prevalent in the elderly...
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Differences in characteristics of somatosensory evoked potentials between children and adults The...
Differences in characteristics of somatosensory evoked potentials between children and adultsThe present study examined the characteristics of somatosensory processing in healthy prepubescent children (mean age: 124.9 ± 3.8 months) compared with young adults. Somatosensory evoked potentials at the frontal (Fz) and centroparietal (C3′) electrodes were recorded by delivering an electrical stimulus to the right median nerve at a rate of 3 Hz. The characteristics of somatosensory evoked potential waveforms...
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The prevalence of oral High‐risk HPV infection in Indonesian oral squamous cell carcinoma patientsAbstract Objectives The objective of this study was to report the integrated observations of high‐risk HPV‐related oral squamous carcinoma (OSCC) at our national referral center for cancer, the Dharmais National Cancer Hospital (DNCH), Jakarta, from 2003 to 2013. Materials And Methods Seventy‐eight formalin fixed paraffin embedded specimens obtained from OSCC cases were collected from 2003 to 2013 DNCH...
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Gilteritinib or Chemotherapy for Relapsed or Refractory FLT3-Mutated AMLPatients with acute myeloid leukemia (AML) whose disease is refractory to, or relapses after, induction chemotherapy have a dismal prognosis with standard chemotherapy. FMS-like tyrosine kinase 3 (FLT3), a cytokine receptor tyrosine kinase that is expressed in early hematopoietic stem and…The New England Journal of Medicine: Search Results in Hematology\OncologyThu Oct 31, 2019 02:00Rat Bite FeverFigure 1.The New England Journal...
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Altered RNA Processing in Cancer Pathogenesis and Therapy [Review]Major advances in our understanding of cancer pathogenesis and therapy have come from efforts to catalog genomic alterations in cancer. A growing number of large-scale genomic studies have uncovered mutations that drive cancer by perturbing cotranscriptional and post-transcriptional regulation of gene expression. These include alterations that affect each phase of RNA processing, including splicing, transport, editing, and decay of...
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Treatment of metastatic malignant melanoma during pregnancy with a BRAF kinase inhibitor: A case reportConclusionMalignancy during pregnancy poses both medical and ethical dilemmas in the management and treatment of cancer. The treatment of late-stage melanoma in pregnancy with a BRAF kinase inhibitor may be an option. (Source: Case Reports in Womens Health)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.MedWorm...
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Micrometastases and Angiogenesis in Colon Cancer. Prognostic Value of VEGF.Conditions: Colorectal Cancer; Angiogenesis Intervention: Procedure: COLORECTAL CANCER SURGERY Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Recruiting (Source: ClinicalTrials.gov)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm...
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Palladium(II) complexes with thiosemicarbazones derived from pyrene as topoisomerase IB inhibitorsThis article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Carolina G. Oliveira, Isolda Romero-Canel ón, Monize M. Silva, James P. C. Coverdale, Pedro Ivo S. Maia, Alzir A. Batista, Silvia Castelli, Alessandro Desideri, Peter J. Sadler, Victor M. Deflon New palladium complexes exhibit potent antiproliferative activity against A2780 and cisplatin-resistant A2780C is human ovarian...
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[ASAP] Donor –Acceptor-Type Conjugated Polymer-Based Multicolored Drug Carriers with Tunable Aggregation-Induced Emission Behavior for Self-Illuminating Cancer TherapyACS Applied Materials& InterfacesDOI: 10.1021/acsami.9b11237 (Source: ACS Applied Materials and Interfaces)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.MedWorm Cancer & Oncology ResearchThu Oct 31, 2019 05:00[ASAP] Single-Stranded DNA-Packaged...
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Pulsed Reduced Dose Rate for Reirradiation of Recurrent Breast CancerConclusionsPRDR radiation therapy with capecitabine was a well-tolerated and effective method for treating patients with recurrent breast cancer. Prospective studies are necessary to compare side effects and efficacy with conventional dose rate reirradiation and to evaluate the potential role for capecitabine in the recurrent setting. (Source: Practical Radiation Oncology)MedWorm Cancer & Oncology ResearchThu Oct 31, 2019 22:44Letter...
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Anal mycobacterial infections†ConclusionsMycobacterial infections of the anus and perineum are rare. The most common clinical presentations are the presence of ulceration and fistulization. The diagnosis involves more than one procedure for identifying the bacilli and should consider the presence of manifestations in more than one organ. The treatment is based on pharmacological intervention. Surgery is recommended for acute complications or chronic sequelae of the disease.ResumoIntroduçãoInfecções...
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Evaluation of Prognostic Monitoring for Triple Negative Breast Cancer PatientsCondition: Triple Negative Breast Cancer Intervention: Sponsor: Peking Union Medical College Hospital Recruiting (Source: ClinicalTrials.gov)MedWorm Cancer & Oncology Clinical TrialsThu Oct 31, 2019 17:00Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic CancerConditions: Pancreatic Cancer; Pancreatic Neoplasms; Pancreatic Ductal Adenocarcinoma; Advanced Cancer Interventions:...
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Measles wipes out immune system's memory, study findsScientists say threat posed by measles is 'much greater than we previously imagined'Measles causes long-term damage to the immune system, leaving children who have had it vulnerable to other infections long after the initial illness has passed, research has revealed.Two studies of unvaccinated children in an Orthodox Protestant community in the Netherlands found that measles wipes out the immune system 's memory of previous illnesses, returning...
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An unusual case of pulmonary arterio-venous fistula (PAVF)Ajay Kumar Jha, Ashok SunderJournal of Family Medicine and Primary Care 2019 8(10):3408-3411 Pulmonary Arteriovenous Fistula (PAVF) is an abnormal communication between the pulmonary veins and pulmonary arteries. Most individuals may have the condition since birth (congenital occurrence), but it can also be an acquired condition. Most individuals with Pulmonary Arteriovenous Fistula also have a hereditary haemorrhagic telangiectasia. The common...
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Role of epidemiological risk factors in improving the clinical diagnosis of streptococcal sore throat in pediatric clinical practiceKapil Bhalla, Parveen Bhardwaj, Ashish Gupta, Shuchi Mehra, Deepak Nehra, Sanjiv NandaJournal of Family Medicine and Primary Care 2019 8(10):3130-3135 Background and Aims: Antibiotics are frequently prescribed for sore throat in developing countries, that in turn leads to huge healthcare expenditure and their irrational use may lead to antimicrobial resistance in the...
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Left atrial isomerism associated with aneurysmal enlargement of right atrial appendage: A case report with literature reviewPrateek Agarwal, Rajesh Kumar AgarwalIndian Journal of Radiology and Imaging 2019 29(3):318-323 We present a prenatally diagnosed case of heterotaxy syndrome (HS) in which left atrial isomerism (LAI) was associated with an aneurysmal enlargement of the right atrial appendage (RAA). Although LAI is usually associated with complex cardiac and extracardiac anomalies, the association...
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Post-operative haemorrhage after acute bilateral tonsillectomy in patients with peritonsillar abscess: prevalence, treatment, risk factors, and side of bleeding.Acta Oto-Laryngologica: Table of Contents: Taylor and FrancisThu Oct 31, 2019 10:17Evaluation of appearance-related distress after canaloplasty using the DAS-24 questionnaire.Acta Oto-Laryngologica: Table of Contents: Taylor and FrancisThu Oct 31, 2019 10:03Longterm results after tonsillotomy: outcome, residual symptoms and need for revision...
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Genetic Modification of Cyanobacteria by Conjugation Using the CyanoGate Modular Cloning ToolkitHere, we present a protocol describing how to i) assemble a self-replicating vector using the CyanoGate modular cloning toolkit, ii) introduce the vector into a cyanobacterial host by conjugation, and iii) characterize transgenic cyanobacteria strains using a plate reader or flow cytometry.JoVE: Journal of Visualized ExperimentsThu Oct 31, 2019 21:03High-Contrast and Fast Photorheological Switching of...
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[ASAP] Fluorescence Imaging of Bacterial Killing by Antimicrobial Peptide Dendrimer G3KLACS Infectious DiseasesDOI: 10.1021/acsinfecdis.9b00299ACS Infectious Diseases: Latest Articles (ACS Publications)Thu Oct 31, 2019 06:00An unusual case of cutaneous feline pythiosisPublication date: Available online 31 October 2019Source: Medical Mycology Case ReportsAuthor(s): Megan Dowst, Alana Pavuk, Raquel Vilela, Camila Vilela, Leonel MendozaAbstractPythiosis is frequently reported in dogs and horses inhabiting...
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The effects of Rhodopseudomonas palustris PSB06 and CGA009 with different agricultural applications on rice growth and rhizosphere bacterial communitiesIn recent years, the photosynthetic bacteria have been used widely in agriculture, but the effects of different agricultural applications on crop rhizosphere microorganism and crops are lack. In this study, we...AMB Express - Latest ArticlesThu Oct 31, 2019 02:00Effect of bovine lactoferrin as a novel therapeutic agent in a rat model of sepsis-induced...
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Adenochondroma of the Thyroid in a 3-Year-Old Female: A Case Report.Related ArticlesAdenochondroma of the Thyroid in a 3-Year-Old Female: A Case Report. Ear Nose Throat J. 2019 Oct 30;:145561319881504 Authors: Teplitzky TB, Okonkwo N, Papadimitriou JC, Pereira KD Abstract Follicular adenomas are the most common benign thyroid neoplasm but are unusual in children. However, other rare degenerative lesions and those of developmental origin can also present as thyroid masses. This article reports the...
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Evaluation of IL6, IL10 and VDR alleles distribution in an Italian large sample of subjects affected by chronic periodontal disease.Related ArticlesEvaluation of IL6, IL10 and VDR alleles distribution in an Italian large sample of subjects affected by chronic periodontal disease. Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419840844 Authors: Luca S, Francesco C, Damiano M, Alessandro N, Silvia C, Diego R, Michele R, Marco S Abstract In recent decades, the role played by the immune response...
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Standards for European training requirements in interventional neuroradiologyAbstract This document sets out standards for training in Interventional Neuroradiology (INR) in Europe. These standards have been developed by a working group of the European Society of Neuroradiology (ESNR) and the European Society of Minimally Invasive Neurological Therapy (ESMINT) on the initiative and under the umbrella of the Division of Neuroradiology/Section of Radiology of the European Union of Medical Specialists...
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The Power of Positive Psychology.Related ArticlesThe Power of Positive Psychology. J Pediatr Health Care. 2018 Nov - Dec;32(6):533 Authors: Swartz MK PMID: 30368307 [PubMed - indexed for MEDLINE]pubmed: philosophy for medic...Thu Oct 31, 2019 12:06Nonagenarians qualify for total knee arthroplasty: a report on 329 patients from the Swedish Knee Arthroplasty Register 2000-2016.Related ArticlesNonagenarians qualify for total knee arthroplasty: a report on 329 patients from the Swedish Knee Arthroplasty...
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Verrucous dysplasia or verrucous hyperplasia: Clarity in terminology.Related ArticlesVerrucous dysplasia or verrucous hyperplasia: Clarity in terminology. Oral Oncol. 2019 Oct 26;:104457 Authors: Shah A, Desai RS, Shirsat P, Bansal S, Prasad P PMID: 31662232 [PubMed - as supplied by publisher]pubmed: "oral oncol"[jour]Thu Oct 31, 2019 13:00Circadian Clocks in the Regulation of Neurotransmitter Systems.Related ArticlesCircadian Clocks in the Regulation of Neurotransmitter Systems. Pharmacopsychiatry....
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Fear in dreams and in wakefulness: Evidence for day/night affective homeostasis.Related ArticlesFear in dreams and in wakefulness: Evidence for day/night affective homeostasis. Hum Brain Mapp. 2019 Oct 30;: Authors: Sterpenich V, Perogamvros L, Tononi G, Schwartz S Abstract Recent neuroscientific theories have proposed that emotions experienced in dreams contribute to the resolution of emotional distress and preparation for future affective reactions. We addressed one emerging prediction, namely...
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Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast CancerDespite effective strategies, resistance in HER2+ breast cancer remains a challenge. While the mevalonate pathway (MVA) is suggested to promote cell growth and survival, including in HER2+ models, its potential role in resistance to HER2-targeted therapy is unknown. Parental HER2+ breast cancer cells and their lapatinib-resistant and lapatinib + trastuzumab–resistant derivatives were used for this...
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Which Recurrent Selection Scheme To Improve Mixtures of Crop Species? Theoretical ExpectationsIn a context of increasing environmental challenges, there is an emerging demand for plant cultivars that are adapted to cultivation in species mixture. It is thus pressing to look for the optimization of selection schemes to grow species mixtures, and especially recurrent selection schemes which are at the core of the improvement of many plant species. We considered the case of two populations from different...
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[ASAP] Headspace Passive Dosing of Volatile Hydrophobic Organic Chemicals from a Lipid Donor—Linking Their Toxicity to Well-Defined Exposure for an Improved Risk AssessmentEnvironmental Science & TechnologyDOI: 10.1021/acs.est.9b04681Environmental Science & Technology: Latest Articles (ACS Publications)Thu Oct 31, 2019 06:00[ASAP] First Quantification of the Controlling Role of Humic Substances in the Transport of Iron Across the Surface of the Arctic OceanEnvironmental Science & TechnologyDOI:...
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A missense mutation in <i>SNRPE</i> linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicingby Tao Chen, Bin Zhang, Thomas Ziegenhals, Archana B. Prusty, Sebastian Fröhler, Clemens Grimm, Yuhui Hu, Bernhard Schaefke, Liang Fang, Min Zhang, Nadine Kraemer, Angela M. Kaindl, Utz Fischer, Wei Chen Malfunction of pre-mRNA processing factors are linked to several human diseases including cancer and neurodegeneration. Here we report the identification of a...
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Finger-pressing: a simple and efficient way to stop chyle leak post neck dissectionAbstract Purpose Postoperative chyle leak (CL) is a rare but severe complication after neck dissection. Conservative first-line treatments, such as total parenteral nutrition (TPN), octreotide and pressure dressing, can significantly prolong the hospital stay. Efficient and well-tolerated conservative treatment options are still lacking. Methods We have developed...International journal of basic and clinical endocrinologyThu...
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Development of Therapeutic Anti-JAGGED1 Antibodies for Cancer Therapy The role of Notch signaling...
Development of Therapeutic Anti-JAGGED1 Antibodies for Cancer TherapyThe role of Notch signaling and its ligand JAGGED1 (JAG1) in tumor biology has been firmly established, making them appealing therapeutic targets for cancer treatment. Here, we report the development and characterization of human/rat-specific JAG1-neutralizing mAbs. Epitope mapping identified their binding to the Notch receptor interaction site within the JAG1 Delta/Serrate/Lag2 domain, where E228D substitution prevented effective...
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Point-of-Care Ultrasound and the Septic Prosthetic Hip JointPublication date: Available online 31 October 2019Source: The Journal of Emergency MedicineAuthor(s): Rachel R. Bengtzen, Jesse LeeAbstractSeptic joints can have an insidious onset and are difficult to diagnosis. Diagnosis can be more complicated in the setting of a distant prosthetic joint. Plain films and inflammatory markers are not specific and magnetic resonance imaging (MRI) is not a timely test in the emergency department. Computed...
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Epithelioid Rhabdomyosarcoma: Report of a Cutaneous Case and Literature Review of a Recently Described Variant of RhabdomyosarcomaAbstract: Rhabdomyosarcoma affects mainly pediatric patients and is currently classified into 4 categories: embryonal, alveolar, pleomorphic, and spindle cell/sclerosing. Epithelioid rhabdomyosarcoma is a recently described variant of rhabdomyosarcoma in which primary cutaneous presentation is infrequent. In this brief report, we describe a rare case of epithelioid rhabdomyosarcoma...
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Pneumonia due to aspiration of povidine iodine after preoperative disinfection of the oral cavity...
Pneumonia due to aspiration of povidine iodine after preoperative disinfection of the oral cavityAbstract Introduction Povidone-iodine (PI) is thought to be an effective disinfectant and safe for many surgeons. Aspiration pneumonia is usually caused by gastric contents, but if PI solution will be aspirated, pneumonia or other complications may occur. Case report We present a case of pneumonia to aspiration of PI solution in a 91-year-old man patient...Latest Results for Oral and Maxillofacial Surgery02:00Can...
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Samenvatting: Octapharma kondigt publicatie aan van gegevens over fibryga® voor de behandeling van verworven fibrinogeengebrek bij patiënten die een hartoperatie ondergaanLACHEN, Zwitserland--(BUSINESS WIRE)--Octapharma heeft een publicatie aangekondigd van nieuwe gegevens die aantonen dat het fibrinogeenconcentraat fibryga® een effectief alternatief is voor cryoprecipitaat voor patiënten met ernstige bloedingen tijdens een hartchirurgie. De gegevens zijn onlangs gepubliceerd in de Journal of the...
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Octapharma meldet Veröffentlichung von Daten zu fibryga® für die Behandlung des erworbenen Fibrinogenmangels bei Patienten, die am Herzen operiert werdenLACHEN, Schweiz--(BUSINESS WIRE)--Octapharma meldet die Veröffentlichung neuer Daten, aus denen hervorgeht, dass das Fibrinogenkonzentrat fibryga® bei Patienten, die während einer Herzoperation schwere Blutungen erleiden, eine wirksame Alternative zum Kryopräzipitat darstellt. Die Daten wurden vor kurzem im Journal of the American Medical Association...
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Sustained GRK2-dependent CREB activation is essential for α<sub>2</sub>-adrenergic receptor-induced PC12 neuronal differentiationPublication date: Available online 31 October 2019Source: Cellular SignallingAuthor(s): George Karkoulias, Katie A. McCrink, Jennifer Maning, Celina M. Pollard, Victoria L. Desimine, Nicholas Patsouras, Miltiades Psallidopoulos, Stavros Taraviras, Anastasios Lymperopoulos, Christodoulos FlordellisAbstractMany aspects of neuronal development, such as neuronal...
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Unknowing ingestion of Brugmansia suaveolens leaves presenting with signs of anticholinergic toxicity: a case reportBrugmansia suaveolens is the commonest species under the Solanacea ("Angels Trumpet" in English; "Attana" in Sinhalese) plant family in Sri Lanka. It contains alkaloids like scopolamine, atropine and hyoscyamine ...Journal of Medical Case Reports - Latest ArticlesWed Oct 30, 2019 02:00Case 34-2019: A 16-Year-Old Boy with JaundicePresentation of Case. Dr. Akash Gupta (Pediatrics): A...
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Cancers, Vol. 11, Pages 1693: How Do Synchronous Lung Metastases Influence the Surgical Management of Children with Hepatoblastoma? An Update and Systematic Review of the LiteratureCancers, Vol. 11, Pages 1693: How Do Synchronous Lung Metastases Influence the Surgical Management of Children with Hepatoblastoma? An Update and Systematic Review of the Literature Cancers doi: 10.3390/cancers11111693 Authors: Roberta Angelico Chiara Grimaldi Carlo Gazia Maria Cristina Saffioti Tommaso Maria Manzia Aurora...
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Danish Team Discovers Possible Cancer Culprit: 'Protein Scaffolding' for DNA RepairA relatively enormous 'protein scaffolding' network that stabilizes and then fixes DNA damage was found to be a potential cause of cancer by a team of scientists in Denmark if the mechanism utilizing the proteins 53BP1 and RIF1 malfunctions. The resulting pathway could be the culprit behind some diseases, according t o the results reported in the journal Nature. (Source: CancerNetwork)CancerNetworkThu Oct 31, 2019...
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Characterizing and assessing antiemetic underuse in patients initiating highly emetogenic chemotherapyAbstract Background Patients initiating highly emetic chemotherapy (HEC) are at a 90% risk of chemotherapy-induced nausea and vomiting (CINV). Despite guideline-concordant antiemetic prescribing preventing CINV in up to 80% of patients, studies suggest that guideline-concordant antiemetic regimen use by patients initiating HEC is sub-optimal. However, these studies have been limited to single-site...
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UNITY-NHL Trial 's Follicular Lymphoma Cohort Meets Primary Endpoint of Improved ORR: Treatment with umbralisib monotherapy demonstrated improved overall response rates among patients with follicular lymphoma. (Source: CancerNetwork)
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The Association between Prebiotic Fiber Supplement Use and Colorectal Cancer Risk and Mortality in the Women's Health InitiativeBackground:Fiber-based prebiotic supplements are marketed for maintaining bowel health and promoting beneficial gut bacteria. However, the association between prebiotic supplement use and colorectal cancer risk and mortality is unknown. Methods:The association between prebiotic use and colorectal cancer risk and mortality was evaluated in postmenopausal women in the Women's...
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We've finally figured out what happens when a star explodesExplosions normally require a build-up of pressure, so how can they occur in the vacuum of space when a star goes supernova? Now we have the answerNew Scientist - The Human BrainThu Oct 31, 2019 20:00Measles has a devastating and long-term effect on your immune systemMeasles makes children vulnerable to other infections and now we know why – it wipes a large part of the immune system's memory of other pathogensNew Scientist - The Human BrainThu...
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Understanding data and information needs for palliative cancer care to inform digital health intervention development in Nigeria, Uganda and Zimbabwe: protocol for a multicountry qualitative studyIntroductionPalliative care is a clinically and cost-effective component of cancer services in sub-Saharan Africa (SSA). Despite the significant need for palliative cancer care in SSA, coverage remains inadequate. The exploration of digital health approaches could support increases in the quality and reach...
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Epidermal Display Screens for On-Body Flexible Medical DevicesResearchers from Nanjing University in China have developed a way to place displays on human skin that are flexible, safe, and don't require a lot of power to run. The technology will certainly have implications for the field of wearable devices by allowing already existing flexible medical devices to display relevant biomedical information. Schematic showing the structure of a stretchable alternating current electroluminescent (ACEL)...
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High-throughput ultra-sensitive discrimination of single nucleotide polymorphism via click chemical ligationAnalyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01672D, PaperQianyu Zhou, Xinying Zhong, Lingli Zhao, Lijuan Wang, Yinglin Zhou, Xinxiang ZhangSingle nucleotide polymorphisms (SNPs) have been proven to be important biomarkers for disease diagnosis, prognostics and disease pathogemsis. Here, taking the advantages of a self-assemble oligonucleotide sandwich structure and robust...The content...
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50th anniversary of <em>Human Pathology</em>Publication date: Available online 30 October 2019Source: Human PathologyAuthor(s): Lori A. EricksonHuman PathologyThu Oct 31, 2019 20:24Predictive value of WHO classification for PD-L1 and Her2/Neu expression and distinct associations with protein expression based classification in gastric carcinomaPublication date: Available online 30 October 2019Source: Human PathologyAuthor(s): Namrata Setia, Sangjeong Ahn, Hye S Han, Do Youn Park, Gregory...
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Supraglottic airway versus endotracheal tube during interventional pulmonary procedures – a retrospective studyAs the field of interventional pulmonology (IP) expands, anesthesia services are increasingly being utilized when complex procedures of longer duration are performed on sicker patients with high risk co-morbid...BMC Anesthesiology - Latest ArticlesThu Oct 31, 2019 02:00Red blood cell transfusion in surgery: an observational study of the trends in the USA from 2011 to 2016Summary Guidelines...
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Plasma cytokine profiles associated with rhodesiense sleeping sickness and falciparum malaria co-infection in North Eastern UgandaImmunological Human African Trypanosomiasis (HAT) studies often exclude malaria, although both infections overlap in specific endemic areas. During this co-infection, it is not known whether this parasitic int...Allergy, Asthma & Clinical Immunology - Latest ArticlesWed Oct 30, 2019 02:00The TNF-like weak inducer of the apoptosis/fibroblast growth factor–inducible...
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Hyperbaric Oxygen Therapy for Non‐Ischemic Diabetic Ulcers: A Systematic Review ABSTRACT Diabetic...
Hyperbaric Oxygen Therapy for Non‐Ischemic Diabetic Ulcers: A Systematic ReviewABSTRACT Diabetic foot ulcers are a common complication of diabetes, which affects 25% of patients and may ultimately lead to amputation of affected limbs. Research suggests hyperbaric oxygen therapy improves healing of these ulcers. However, this has not been reflected in previous reviews, possibly because they did not differentiate between patients with and without peripheral arterial occlusive disease. Therefore, we...
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Single Syringe Administration of Diluted AdenosineAbstract Study hypothesis: A single‐syringe of adenosine diluted in normal saline will be non‐inferior to the standard two‐syringe method for conversion of supraventricular tachycardia to normal sinus rhythm. Objective: To compare the relative efficacy and safety of a novel route of administration of adenosine to usual care. Methods: A single center, prospective, observational study was conducted from November 1, 2016 through February 28, 2018 on...
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Response to interferon treatment in essential thrombocythemia with inv(3)(q21q26)Latest Results for Annals of Hematology02:00Serum gamma-glutamyltransferase, oxidized LDL and mortality in the elderlyAbstract Background Serum gamma-glutamyltransferase (GGT) is a liver enzyme involved in the metabolism of glutathione (GSH), a major antioxidant in humans. GGT is a risk factor for mortality in young and middle-aged individuals but this association has been poorly investigated in the elderly. Methods...
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Comparative Secretome Analyses of Primary Murine White and Brown Adipocytes Reveal Novel Adipokines.
Comparative Secretome Analyses of Primary Murine White and Brown Adipocytes Reveal Novel Adipokines.: Related ArticlesComparative Secretome Analyses of Primary Murine White and Brown Adipocytes Reveal Novel Adipokines.Mol Cell Proteomics. 2018 12;17(12):2358-2370Authors: Ali Khan A, Hansson J, Weber P, Foehr S, Krijgsveld J, Herzig S, Scheideler MAbstract The adipose organ, including white and brown adipose tissues, is an important player in systemic energy homeostasis, storing excess energy...
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Mitochondrial Dysfunction in Cardiac SurgeryPublication date: Available online 12 October 2019Source: Anesthesiology ClinicsAuthor(s): Anne D. CherryEthical Considerations for Mechanical SupportPublication date: Available online 11 October 2019Source: Anesthesiology ClinicsAuthor(s): Darryl Abrams, J. Randall Curtis, Kenneth M. Prager, A. Reshad Garan, Jonathan Hastie, Daniel BrodieAssessing Right Ventricular Function in the Perioperative Setting, Part II—What About Catheters?Publication date: Available...
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Healing the heart of healthcare: Leaving no one behind: Impact of 15th World Rural Health Conference New DelhiRaman Kumar, Pratyush KumarJournal of Family Medicine and Primary Care 2019 8(10):3077-3082More than a 1,000 delegates from 40 countries participated in the 15th WONCA World Rural Health Conference held at India Habitat Centre, New Delhi, from 26-29th April, 2018. The theme of this conference was "Healing the Heart of Healthcare - Leaving no one behind". The conference was organized by the...
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CopyrightPublication date: November 2019Source: Neuroimaging Clinics of North America, Volume 29, Issue 4Author(s):Rapid On-site Evaluation of Spine LesionsPublication date: November 2019Source: Neuroimaging Clinics of North America, Volume 29, Issue 4Author(s): Israh Akhtar, Varsha ManuchaIntroduction to Diagnostic and Therapeutic Spinal AngiographyPublication date: November 2019Source: Neuroimaging Clinics of North America, Volume 29, Issue 4Author(s): Philippe GailloudSpontaneous Intracranial...
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Optimal Management of Hypotension During Cesarean Delivery Under Spinal AnesthesiaPublication date: December 2019Source: Advances in Anesthesia, Volume 37Author(s): Jennifer L. Fichter, Kenneth E. NelsonUltrasound-Guided Fascial Plane Blocks of the Thorax: Pectoral I and II, Serratus Anterior Plane, and Erector Spinae Plane BlocksPublication date: December 2019Source: Advances in Anesthesia, Volume 37Author(s): Ki Jinn Chin, Amit Pawa, Mauricio Forero, Sanjib AdhikarySpinal Cord and Peripheral Nerve...
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Directory: AAO Officers and OrganizationsPublication date: November 2019Source: American Journal of Orthodontics and Dentofacial Orthopedics, Volume 156, Issue 5Author(s):November 2019:156(4)Publication date: November 2019Source: American Journal of Orthodontics and Dentofacial Orthopedics, Volume 156, Issue 5Author(s): Allen H. MoffittI don't have to tell you thatPublication date: November 2019Source: American Journal of Orthodontics and Dentofacial Orthopedics, Volume 156, Issue 5Author(s): Laurance...
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Applying luminescence dating of ceramics to the problem of dating Arctic archaeological sitesPublication date: December 2019Source: Journal of Archaeological Science, Volume 112Author(s): Shelby L. Anderson, James K. FeathersAbstractDating Arctic archaeological sites is challenging because of limited terrestrial bone and the high probability of old wood in northern regions. Luminescence dating of ceramic materials, abundant in western Arctic late Holocene archaeological sites, offers another potential...
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Diagnostic accuracy and clarity of steady-state free precession imaging of cardiac valve morphology in congenital heart diseaseOscar J Benavidez, Ashwin Prakash, Kimberlee Gauvreau, Tal GevaArchives of Cardiovascular Imaging 2018 6(1):1-6Purpose: Evaluation of cardiac valve morphology has not been considered an indication for cardiac magnetic resonance imaging (MRI) due to suboptimal imaging quality. Our study aims to evaluate cine of cardiac magnetic resonance-steady-state free precession (CMR-SSFP)...
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Inter-rater reliability of primitive signs in dementiaPublication date: December 2019Source: Clinical Neurology and Neurosurgery, Volume 187Author(s): Andrea Plutino, Sara Baldinelli, Chiara Fiori, Valentina Ranaldi, Mauro Silvestrini, Simona LuzziAbstractObjectivesThe aim of the present study is to explore inter-rater reliability of primitive signs in a group of patients assessed for dementia.Patients and methods97 patients admitted to our University Hospital for cognitive impairment were enrolled...
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CT FFR A paradigm shift in evaluation of coronary artery diseaseAnirudh KohliIndian Journal of Radiology and Imaging 2019 29(3):233-235Imaging protocols for CT chest: A recommendationAshu Seith Bhalla, Abanti Das, Priyanka Naranje, Aparna Irodi, Vimal Raj, Ankur GoyalIndian Journal of Radiology and Imaging 2019 29(3):236-246Computed Tomography (CT) is the mainstay of diagnostic imaging evaluation of thoracic disorders. However, there are a number of CT protocols ranging from a simple non-contrast...
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Vestibular Implantation and the Feasibility of Fluoroscopy-Guided Electrode InsertionRecent research has shown promising results for the development of a clinically feasible vestibular implant in the near future. However, correct electrode placement remains a challenge. It was shown that fluoroscopy was able to visualize the semicircular canal ampullae and electrodes, and guide electrode insertion in real time. Ninety-four percent of the 18 electrodes were implanted correctly (<1.5 mm distance...
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Testosterone downregulates angiotensin II type-2 receptor via androgen receptor-mediated ERK1/2 MAP kinase pathway in rat aorta by Jay S Mishra et al.Is angiotensin-(3–4) (Val-Tyr), the shortest angiotensin II-derived peptide, opening new vistas on the renin–angiotensin system? by Juliana Dias et al.Circulating ACE2 activity correlates with cardiovascular disease development by Katalin Úri et al.Recruitment of macrophages from the spleen contributes to myocardial fibrosis and hypertension induced...
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Share: How does Elevo® differ from other palatal implants for the treatment of snoring?The Elevo® Snoring Intervention Set contains three fully resorbable suture implants, which reduce the risk of extrusions that may occur with non-resorbable implants. The implants are composed of polydioxanone, which has been found to be non-antigenic and degrades into two substances that are both endogenous to the body: lactic acid and water. The material is completely reabsorbed into the body within six months...
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National Diabetes Month — November 2019Diabetes Prevalence and Incidence Among Medicare Beneficiaries — United States, 2001–2015Linda J. Andes, PhD; Yanfeng Li, MD; Meera Srinivasan, MS; et al.Racial/Ethnic and Age Group Differences in Opioid and Synthetic Opioid–Involved Overdose Deaths Among Adults Aged ≥18 Years in Metropolitan Areas — United States, 2015–2017Kumiko M. Lippold, PhD; Christopher M. Jones, PharmD; Emily O'Malley Olsen, PhD; et al.Tobacco Use in Top-Grossing Movies — United States,...
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Family Health: How Twin Studies Can Help EveryoneTwins are a powerful tool for studying health and disease. They highlight why knowing your family's health history is important. (From NIH News in Health)Basic Science Teaching ResourcesDiscover Pathways, resources that provide lessons, activities, and videos that dive into basic research. (From NIH's NIGMS)Asthma Treatment for African American ChildrenA study shows that African American children with poorly controlled asthma may benefit from different...
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How Do Attending Physicians Prepare Residents to Deliver High-Value, Cost-Conscious Care?Purpose: An estimated 20% of health care expenditures are wasteful. Educational interventions aimed at reducing waste by delivering high-value, cost-conscious care (HV3C) often focus on the role of the physician. This study sought to understand how attending physicians, who have a central role in the workplace, prepare residents to provide HV3C. Method: Researchers from Maastricht University in Maastricht, the...
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Pigment Cell & Melanoma Research,Early ViewOnline Version of Record before inclusion in an issueORIGINAL ARTICLEEvolutionary processes of melanomas from giant congenital melanocytic neviYoungkyoung Lim, Hyun‐Tae Shin, YoungHwan Choi, Dong‐Youn LeeVersion of Record online: 20 October 2019Pigment Cell & Melanoma ResearchAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.ORIGINAL ARTICLESGABA‐A receptor...
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Impact of Remnant Nodules on Immediate and Long-term Outcomes of Voice Therapy for Vocal Fold NodulesIn this study, we aimed to assess whether remnant vocal fold nodules (VFN) influence immediate and long-term voice outcomes after voice therapy.Associations of Education and Training with Perceived Singing Voice Function Among Professional SingersThe educational backgrounds of professional singers vary greatly and span from no formal training to advanced degrees in music or theater. Consequently,...
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Edema facial con fóvea, un importante diagnóstico diferencialPublication date: Available online 23 October 2019Source: Actas Dermo-SifiliográficasAuthor(s): J.G. Chalela, M.I. González, M.F. Ordóñez RubianoBebé con alopecia anular y costras persistentesPublication date: Available online 23 October 2019Source: Actas Dermo-SifiliográficasAuthor(s): E. Macías del Toro, M.A. González Domingo, F. Alfageme RoldánPseudoangiomatosis eruptiva familiar: 2 casos de presentación recurrentePublication date: Available...
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The Current Landscape of Antibacterial SoapsBackground In 2017, the Food and Drug Administration banned the marketing of triclosan and triclocarban in antibacterial soaps, citing inefficacy and concerns of systemic absorption and antibacterial resistance. As a result, there is an anticipated decrease in the number of triclosan-containing products on the market with an associated increase in antibacterial alternatives (eg, benzalkonium chloride, benzethonium chloride, chloroxylenol, chlorhexidine)...
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Acanthosis nigricans in Insulinoma: Reversible experiments of the naturePublication date: Available online 18 October 2019Source: Medical Journal Armed Forces IndiaAuthor(s): Vijay Sheker R. Danda, Paidipally Srinivas Rao, Chaitanya Konda, Piyush LodhaAbstractAcanthosis Nigricans is considered to be a skin marker of insulin resistance and atherosclerosis. It is rarely reported in cases of insulinoma where there is marked hyperinsulinaemia. We report two cases of insulinoma with acanthosis nigricans...
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Parp inhibitors as maintenance treatment in platinum sensitive recurrent ovarian cancer: An updated meta-analysis of randomized clinical trials according to BRCA mutational statusPublication date: November 2019Source: Cancer Treatment Reviews, Volume 80Author(s): Federica Tomao, Erlisa Bardhi, Anna Di Pinto, Carolina Maria Sassu, Elena Biagioli, Maria Cristina Petrella, Innocenza Palaia, Ludovico Muzii, Nicoletta Colombo, Pierluigi Benedetti PaniciAbstractObjectiveThis meta-analysis investigated...
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Personality and the Expression of Symptomatology in Schizophrenia and Bipolar DisorderResearchers and clinicians have begun using dimensions rather than categories to classify psychopathology with a reliance on personality questionnaires to tap traits that can inform dimensional characterizations. A neglected concern is whether in severe psychopathology questionnaire-based assessments of personality reflect a lifetime propensity toward a diagnosis, as some personality-psychopathology models posit,...
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The Benefit of Influenza Vaccines: Beyond Prevention of Clinical InfectionNo abstract availableHighlights of Clinical Practice Guideline for the Management of Asymptomatic Bacteriuria: 2019 Update by the Infectious Diseases Society of AmericaAsymptomatic bacteriuria is a common cause of unnecessary antimicrobial use. The Infectious Diseases Society of America has published an update of the clinical practice guideline for the management of asymptomatic bacteriuria. The guideline provides recommendations...
09:10
Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset DiabetesAbstract: Pancreatitis, a complex disease influenced by both genetic and environmental factors, often leads to metabolic sequelae (such as exocrine pancreatic dysfunction and new-onset diabetes). Several trillion micro-organisms inhabit the gastrointestinal tract, and this community plays an important role in the regulation of functions of not only the gut but also the pancreas. Studies...
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Correction to: Objective and Subjective Effects of a Prototype Nasal Dilator Strip on Sleep in Subjects with Chronic Nocturnal Nasal CongestionThe article "Objective and Subjective Effects of a Prototype Nasal Dilator Strip on Sleep in Subjects with Chronic Nocturnal Nasal Congestion", written by John R. Wheatley, Terence C. Amis, Sharon A. Lee, Renee Ciesla, Gilbert Shanga was originally published electronically on the publisher's internet portal (currently SpringerLink) on May, 22, 2019 without...
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Cultural activity at work: reciprocal associations with depressive symptoms in employeesAbstractPurposeSeveral studies have shown that cultural activities may promote health. There are also prospective population studies which show that regular participation in cultural activities could reduce morbidity and mortality. To what extent such associations could be applied to the work arena is not so well known, although findings in a few studies support the assumption that cultural activities organized...
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A systematic review of the effects of low-frequency repetitive transcranial magnetic stimulation on cognitionThe original version of this article unfortunately contained a mistake. The author would like to include the below acknowledgement section.Bound, free, and total l -dopa measurement in plasma of Parkinson's disease patientsAbstractPeaks and troughs of levodopa in plasma contribute to pulsatile postsynaptic dopamine receptor stimulation in patients with Parkinson's disease. Measurement of levodopa...
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in the final analysisEstablishing Aspirations The 2018 TMS Annual ReportTMS meeting headlines25 Years of Growing the Community: 2018 Annual ReportIn Case You Missed It : Business News from the FieldClassifiedsWhere We've Been and Where We'll GoSolid Oxide Fuel Cells: Recent Scientific and Technological Advancementscall for papersModeling and Simulation of Composite Materials
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Associations of Gray Matter Volume and Perceived Intensity of Bitter Taste: a Voxel-Based Morphometry StudyAbstractIntroductionTwo recent brain morphological studies reported inconsistent results on the neuroanatomical correlates of taste intensity rating among healthy populations. The current study re-visited this issue with a large and more homogeneous sample size. It was hypothesized that the orbitofrontal cortex, the sole region commonly reported by the two studies together with olfactory studies,...
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Orbital complication of acute ethmoiditis: A Tunisian paediatric cross sectional studyAuthor links open overlay panelAsma BenMabroukaSelmenWannesadeMehdiHasnaouibdAminaWerdaniadNouha BenHamidabdSaidaJerbicdNabilDrissbdBahriMahjoubadeaUniversity Hospital Thar Sfar, Mahdia Pediatric Department, 5100 Mahdia, TunisiabUniversity Hospital Thar Sfar, ENT Department, 5100 Mahdia, TunisiacUniversity Hospital Thar Sfar, Radiology Department, 5100 Mahdia, TunisiadMonastir University, Faculty of Medicine, 5019...
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Alternative techniques in cochlear implant surgery: Subtotal petrosectomyAuthor links open overlay panelSantiagoHernándezJuan C.OspinaElisaGutiérrez-GómezMaría TeresaRodríguez-RuizJuan G.TrujilloOtolaryngology and Maxillofacial Surgery Department, San Ignacio University Hospital, Pontificia Universidad Javeriana, Bogotá, ColombiaReceived 28 October 2019, Available online 31 October 2019.Figures (3)https://doi.org/10.1016/j.amjoto.2019.102338Get rights and contentHighlights•Subtotal petrosectomy is...
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Clinical significance of head shake movement in three planes in individuals with dizzinessAuthor links open overlay panelBüşraAltınSongülAksoyDepartment of Audiology, Faculty of Health Sciences, Hacettepe University, 06100, Ankara, TurkeyReceived 7 September 2019, Available online 30 October 2019.Show lesshttps://doi.org/10.1016/j.amjoto.2019.102308Get rights and contentAbstractPurposeThis study aims to evaluate the efficacy of head shake movement on three head movement planes (yaw, pitch and, roll)...
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Therapeutic effects of metformin for noise induced hearing lossAuthor links open overlay panelÖzgeGedikaRemziDoğanbMehmet AliBabademezcErsinKarataşdMehmet ŞerifAydıneAbdurrahimKoçyiğitfMukaddesEşrefoğlugOrhanÖzturanbaBezmialem Vakif University, Faculty of Health Sciences, Audiology Department, Fatih, Istanbul, TurkeybBezmialem Vakif University, Department of Otorhinolaryngology, Fatih, Istanbul, TurkeycAnkara Yildirim Beyazit University, Department of Otorhinolaryngology, Ankara, TurkeydGebze Technical...
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A finite element method for computational full two-body problem: I. The mutual potential and derivatives over bilinear tetrahedron elementsAbstractA finite element method (FEM) for computing the gravitational interactions between two arbitrarily shaped celestial bodies is proposed. Expressions for the gravitational potential, attraction and torques are derived in terms of the finite element mesh division and mass density distribution. This method is implemented to a parallel-simulation package on...
09:03
The Benefit of Influenza Vaccines: Beyond Prevention of Clinical InfectionNo abstract availableHighlights of Clinical Practice Guideline for the Management of Asymptomatic Bacteriuria: 2019 Update by the Infectious Diseases Society of AmericaAsymptomatic bacteriuria is a common cause of unnecessary antimicrobial use. The Infectious Diseases Society of America has published an update of the clinical practice guideline for the management of asymptomatic bacteriuria. The guideline provides recommendations...
09:10
The Amaraughaprabodha: New Evidence on the Manuscript Transmission of an Early Work on Haṭha- and RājayogaAbstractThe Amaraughaprabodha is a Sanskrit Śaiva yoga text attributed by its colophons to Gorakṣanātha. It was first published by Kalyani Devi Mallik in 1954 and has been discussed in various secondary sources. Most notably, Christian Bouy (1994, pp. 18–19) identified this work as a source text for the Haṭhapradīpikā of Svātmārāma (mid-fifteenth century). This article presents new manuscript...
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Ouabain Accelerates Collective Cell Migration Through a cSrc and ERK1/2 Sensitive Metalloproteinase ActivityThe original version of the article unfortunately contained an error in the author group. Dr. Isabel Larré was not submitted and published in the original version.Prevailing Effects of Ibutilide on Fast Delayed Rectifier K + ChannelAbstractEffects of ibutilide, a class III antiarrhythmic drug, on delayed rectifier potassium currents (IK) in freshly isolated guinea pig ventricular myocytes were...
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Time trends in oral bisphosphonate initiation in Ontario, Canada over 20 years reflect drug policy and healthcare delivery changesAbstractSummaryCharacteristics of patients starting oral bisphosphonate therapy changed over time, reflecting trends in osteoporosis management (e.g., new drugs to market), and general healthcare delivery (e.g., benzodiazepine use declined, statin use increased). When designing studies that examine osteoporosis drug effects, potential time-related biases must be considered.IntroductionTo...
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Multiple Group IRT Measurement Invariance Analysis of the Forms of Self-Criticising/Attacking and Self-Reassuring Scale in Thirteen International SamplesAbstractThe purpose of this study was to examine the measurement invariance of the Forms of Self-Criticising/Attacking & Self-Reassuring Scale (FSCRS) in terms of Item Response Theory differential test functioning in thirteen distinct samples (N = 7714) from twelve different countries. We assessed differential test functioning for the three FSCRS...
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Change in MRI findings of medial collateral ligament injury in adolescent baseball players with no clinical symptoms over timeAbstractObjectiveElbow screening of adolescent baseball players began in 2014 using ultrasound, palpation, and dedicated magnetic resonance imaging (MRI). We frequently encountered subjects showing MCL injury on MRI but no clinical symptoms. We assessed variations in asymptomatic MCL injury findings at follow-up MRI, and clarified the pathogenesis of these findings.Materials...
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1q21.1 Deletions and Duplications in 2 Siblings with Psychiatric ProblemsA Girl with Progressive Vision Loss: Diagnostic CluesFamilial Monosomy 7 Syndrome Associated with MyelodysplasiaTop 3 Differentials in Pediatric Radiology: A Case Review – Rebecca Stein-Wexler (ed)A Neonate with Prune Belly Syndrome and Limb Reduction DefectShort Stature in a Girl with Muscular Dystrophy: Double Jeopardy!Necessity of Image Guidance for Subclavian Catheterization to Improve Patient SafetyFamilial Macro-Aspartate...
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Mitteilungen der DGGKünstliche Intelligenz und Robotik – Gedanken eines Baby‑BoomersBeinvenenthrombosen und LungenembolienEndovaskuläres Komplikationsmanagement einer iatrogenen Aortenverletzung während transthorakaler SpondylodeseZusammenfassungDer Fallbericht beschreibt die erfolgreiche endovaskuläre Therapie einer intraoperativen Verletzung der Ao. thoracica descendens im Rahmen einer Re-Spondylodese in einem malignombedingt schwierigen Operationssitus. Die Intervention erfolgte im Sinne der aortalen...
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Systematic Surveys in Informal Settlements: Challenges in Moving Toward Health EquityPerceived Discrimination Based on Criminal Record in Healthcare Settings and Self-Reported Health Status among Formerly Incarcerated IndividualsAbstractPerceived discrimination based on criminal record is associated with social determinants of health such as housing and employment. However, there is limited data on discrimination based on criminal record within health care settings. We examined how perceived discrimination...
08:58
Desmoid-type fibromatosis arising in a bifid rib chest wallAbstractDesmoid-type fibromatosis is a rare soft tissue tumor and the chest wall is one of the common sites of its extra-abdominal occurrence. A bifid rib is one of the congenital rib abnormalities. We report a case of desmoid-type fibromatosis arising in a chest wall's bifid rib. A 42-year-old female complained of right chest pain without remarkable medical, traumatic, or familial history. Chest-computed tomography revealed a chest wall...
08:58
When is Parental Monitoring Effective? A Person-centered Analysis of the Role of Autonomy-supportive and Psychologically Controlling Parenting in Referred and Non-referred AdolescentsAbstractOver the last few years, the protective role of parental monitoring on adolescent adjustment (i.e., active parental efforts aimed at setting limits and tracking adolescents' activities and whereabouts) has been challenged. Recent research has shifted attention to the conditions under which monitoring may be more...
08:48
Research Identifies Earlier Origin of Neural Crest Cells,University of California, Riverside • October 22, 2019ORNL Scientists Shed Light on Microbial 'Dark Matter' with New Approach,Oak Ridge National Laboratory • September 30, 2019
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Pediatric Dermatology,Early View,Online Version of Record before inclusion in an issue,BRIEF REPORTSNovel dermoscopic features of pityriasis versicolor–like macules in epidermodysplasia verruciformisT. P. Afra MD, Keshavamurthy Vinay MD, Muhammed Razmi T MD, Aysha Khader MD, N. A. Bishurul Hafi MDVersion of Record online: 23 October 2019ORIGINAL ARTICLESOcclusive versus neurotoxic agents for topical treatment of head lice infestation: A systematic review and meta‐analysisRowena Natividad S. Flores‐Genuino...
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Chromosomal Abnormalities Associated With Recurrent Miscarriage Emerge from Sequencing Study,Published on Oct 31, 2019 Uganda Genome Resource Sheds Light on Population History, Enables New Association StudiesPublished on Oct 31, 2019 BillionToOne Taps Eluthia as Exclusive Distributor of NIPT in Certain European CountriesPublished on Oct 31, 2019High-Throughput SNP Discovery and Genotyping Using Normalized Genotyping-By-SequencingThis white paper from LGC Group highlights a self-tuning Genotyping-by-Sequencing...
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TABLE OF CONTENTSDecember-2019Volume 55Issue 6CircRNAs: From anonymity to novel regulators of gene expression in cancer (Review)Katherine L. Harper, Euan Mcdonnell, Adrian WhitehouseView Abstract ❯Assessment of biochemical recurrence of prostate cancer (Review)Xiaozeng Lin, Anil Kapoor, Yan Gu, Mathilda Jing Chow, Hui Xu, Pierre Major, Damu TangView Abstract ❯Targeting autophagy is a promising therapeutic strategy to overcome chemoresistance and reduce metastasis in osteosarcomaYu‑Xin Liao, Hai‑Yang...
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Research Articles,Disinfection of Cariogenic Pathogens in Planktonic Lifestyle, Biofilm and Carious Dentine with Antimicrobial Photodynamic Therapy,Minjing Wu, Li Xu, Zhiyu Cai, Shan Huang, Yijun Li, Lishan Lei, Xiaojing HuangVersion of Record online: 22 October 2019We compared the antibacterial effects of antimicrobial photodynamic therapy (aPDT) and 0.12% chlorhexidine (CHX) on Streptococcus mutans and Lactobacillus acidophilus in planktonic lifestyle, biofilm and carious dentine. Samples were...
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MEDICAL NEWS & PERSPECTIVES,Philanthropists Fund Johns Hopkins Center for Study of PsychedelicsRita Rubin, MAMedical News Audio: Philanthropists Fund Johns Hopkins Center for Study of PsychedelicsQuick UptakesMedical Students Around the World Poorly Trained in NutritionJennifer AbbasiViewpoint: Nutrition Education in Medical School, Residency Training, and Practice; Stephen Devries, MD; Walter Willett, MD, DrPH; Robert O. Bonow, MD, MSOriginal Investigation: US Burden of Diseases, Injuries, and...
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ORIGINAL INVESTIGATION,Socioeconomic and Demographic Variation in Insurance Coverage Among Patients With Head and Neck Cancer After the Affordable Care Act,Neelima Panth, MD, MPH; Justin Barnes, MS; Rosh K. V. Sethi, MD, MPH; et al.Comparative Treatment Outcomes for Patients With Idiopathic Subglottic StenosisAlexander Gelbard, MD; Catherine Anderson, BA; Lynne D. Berry, PhD; et al.Audio Interview: Comparative Outcomes of Treatment Options for Patients With Idiopathic Subglottic StenosisCLINICAL...
08:40
Pulmonary Imaging, Electronic Cigarette or Vaping-associated Lung Injury (EVALI): The Tip of the Iceberg, Radiologists will continue to play an important role in understanding and interpreting radiologic findings of lung injury in those with a history of using e-cigarette or vaping products. Suhny Abbara, Fernando Uliana KayOriginal ResearchCardiac CT Diagnostic Performance of On-Site Coronary CT Angiography–derived Fractional Flow Reserve Based on Patient-specific Lumped Parameter Models Diagnostic...
08:31
Associations between Folate Metabolism Enzyme Polymorphisms and Lung Cancer: A Meta-Analysis. In...Associations between Folate Metabolism Enzyme Polymorphisms and Lung Cancer: A Meta-Analysis.In conclusion, this meta-analysis indicated that MTRR rs1801394 was significantly associated with LC in smokers, and MTHFR rs1801133 polymorphisms was also significantly associated with LC in smokers and East Asians. These results suggested that these two polymorphisms could be used to identify individuals at...
Thu Oct 31, 2019 10:30
Associations between Folate Metabolism Enzyme Polymorphisms and Lung Cancer: A Meta-Analysis. In...Associations between Folate Metabolism Enzyme Polymorphisms and Lung Cancer: A Meta-Analysis.In conclusion, this meta-analysis indicated that MTRR rs1801394 was significantly associated with LC in smokers, and MTHFR rs1801133 polymorphisms was also significantly associated with LC in smokers and East Asians. These results suggested that these two polymorphisms could be used to identify individuals at...
Thu Oct 31, 2019 10:30
Associations between Folate Metabolism Enzyme Polymorphisms and Lung Cancer: A Meta-Analysis. In...Associations between Folate Metabolism Enzyme Polymorphisms and Lung Cancer: A Meta-Analysis.In conclusion, this meta-analysis indicated that MTRR rs1801394 was significantly associated with LC in smokers, and MTHFR rs1801133 polymorphisms was also significantly associated with LC in smokers and East Asians. These results suggested that these two polymorphisms could be used to identify individuals at...
Thu Oct 31, 2019 10:30
Cancer, Mixed‐phenotype acute leukemia: A cohort and consensus research strategy from the Children's... Cancer,Mixed‐phenotype acute leukemia: A cohort and consensus research strategy from the Children's Oncology Group Acute Leukemia of Ambiguous Lineage Task ForceBackground Optimal chemotherapy for treating mixed‐phenotype acute leukemia (MPAL) and the role of hematopoietic stem cell transplantation (HSCT) remain uncertain. Major limitations in interpreting available data are MPAL's rarity and...
Wed Oct 30, 2019 09:32
Microorganisms, Vol. 7, Pages 510: Label-Free Quantitative Acetylome Analysis Reveals Toxoplasma gondii Genotype-Specific Acetylomic SignaturesMicroorganisms, Vol. 7, Pages 510: Label-Free Quantitative Acetylome Analysis Reveals Toxoplasma gondii Genotype-Specific Acetylomic Signatures Microorganisms doi: 10.3390/microorganisms7110510 Authors: Ze-Xiang Wang Rui-Si Hu Chun-Xue Zhou Jun-Jun He Hany M. Elsheikha Xing-Quan Zhu Distinct genotypic and pathogenic differences exist between Toxoplasma gondii...
Wed Oct 30, 2019 09:38
Children, Vol. 6, Pages 119: Chest Compressions for Bradycardia during Neonatal Resuscitation—Do We Have Evidence?Children, Vol. 6, Pages 119: Chest Compressions for Bradycardia during Neonatal Resuscitation—Do We Have Evidence? Children doi: 10.3390/children6110119 Authors: Agrawal Lakshminrusimha Chandrasekharan The International Liaison Committee on Resuscitation (ILCOR) recommends the initiation of chest compressions (CC) during neonatal resuscitation after 30 s of effective ventilation if the...
Wed Oct 30, 2019 09:36
Antibiotics, Vol. 8, Pages 203: Nursing Students' Knowledge and Awareness of Antibiotic Use, Resistance and Stewardship: A Descriptive Cross-Sectional StudyAntibiotics, Vol. 8, Pages 203: Nursing Students' Knowledge and Awareness of Antibiotic Use, Resistance and Stewardship: A Descriptive Cross-Sectional Study Antibiotics doi: 10.3390/antibiotics8040203 Authors: Andrea Rábano-Blanco Eva María Domínguez-Martís Diego Gabriel Mosteiro-Miguéns Manuel Freire-Garabal Silvia Novío Antibiotic resistance...
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