Monday, January 7, 2019

Thiourea participation in [3+2] cycloaddition with donor-acceptor cyclopropanes: a domino process to 2-amino-dihydrothiophenes

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C8CC09595G, Communication
Hai-Ming Guo, Ming-Sheng Xie, Guo-Feng Zhao, Tao Qin, Yong-Bo Suo, Gui-Rong Qu
The Yb(OTf)3-catalyzed [3+2] cycloaddition of donor-acceptor cyclopropanes with thiourea offers an efficient route to diverse 2-amino-4,5-dihydrothiophenes (up to 92% yield), in which optically active 2-amino-dihydrothiophenes can be produced from enantiomerically...
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