Thursday, January 3, 2019

Directing GDNF-Mediated Neuronal Signaling with Proactively Programmable Cell-Surface Saccharide-Free Glycosaminoglycan Mimetics

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C8CC09253B, Communication
Song-Gil Lee, Shuting Cai, Daniel Hartoyo Lukamto, Jerry Toh, Roland G. Huber, Peter J Bond, Joo-Eun Jee, Teck Chuan Lim, Pei Liu, Liwei Chen, Vicky Qianqian Qu, Su Seong Lee
A significant barrier to harnessing the power of cell-surface glycosaminoglycans (GAGs) to modulate Glial cell-line-derived neurotrophic factor (GDNF) signaling is the difficulty in accessing key GAG structures involved. Here, we...
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