Thursday, January 3, 2019

An immuno-potentiating vehicle made of mesoporous silica-zinc oxide micro-rosettes with enhanced doxorubicin loading for combined chemoimmunotherapy

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Chem. Commun., 2019, Advance Article
DOI: 10.1039/C8CC09044K, Communication
Guowen Qian, Xiupeng Wang, Xia Li, Atsuo Ito, Yu Sogo, Jiandong Ye
MS-Zn-DOX in combination with PIC not only significantly inhibit tumor growth, but also effectively rejects tumor metastasis in vivo, obviously improving CD4+ and CD8+ T cell populations and IFN-γ secretion in splenocytes of mice.
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