Thursday, January 3, 2019

Chemical and Mechanistic Analysis of Photodynamic Inhibition of Alzheimer’s β-Amyloid Aggregation

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C8CC09288E, Communication
Minkoo Ahn, Byung Il Lee, Sean Chia, Johnny Habchi, Janet Kumita, Michele Vendruscolo, Christopher M Dobson, Chan Beum Park
The self-assembly of the beta-amyloid peptide (Aβ) into amyloid aggregates is a central phenomenon associated with Alzheimer's disease. Here, we report chemical modifications of key amino acid residues of Aβ42...
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