Effect of rifampicin on anticoagulation of warfarin: A case report

paythelady.612 shared this article with you from Inoreader Effect of rifampicin on anticoagulation of warfarin: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Feb 16;9(5):1087-1095. doi: 10.12998/wjcc.v9.i5.1087. ABSTRACT BACKGROUND: The drug interaction between warfarin and rifampicin is widely known, but there are still some difficulties in managing the combination of the two drugs. CASE SUMMARY: A patient with brucellosis received strict monitoring from a Chinese pharmacist team during combination of warfarin and rifampicin. The dose of warfarin was increased to 350% in 3 mo before reaching the lower international normalized ratio treatment window. No obvious adverse reaction occurred during the drug-adjustment period. This is the first case report of long-term combined use of rifampicin and warfarin in patients with brucellosis and valve replacement in China based on the Chinese lower warfarin dose and international normalized ratio range. CONCLUSION: Anticoagulation for valve replacement in Chinese patients differs from that in other races. Establish ment of a pharmacist clinic provides vital assistance in warfarin dose adjustment. PMID:33644171 | PMC:PMC7896655 | DOI:10.12998/wjcc.v9.i5.1087 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.