Animal models of cathartic colon

paythelady.612 shared this article with you from Inoreader Animal models of cathartic colon Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 Feb 26;9(6):1251-1258. doi: 10.12998/wjcc.v9.i6.1251. ABSTRACT The incidence of cathartic colon has been increasing, but satisfactory treatments are still lacking. In order to study the pathological mechanisms of the disorder and identify effective treatment methods, researchers have established different animal models of cathartic colon. This minireview briefly summarizes several common cathartic colon animal models, induced with anthraquinone laxatives such as rhubarb, total anthraquinone, rhein, and emodin, or induced with diphenylmethane laxatives such as phenolphthalein. The advantages and limitations of these models are evaluated and analyzed. We hope that this review will facilitate the selection of suitable models and improve relevant modeling methods. We anticipate the development of more convenient and stable models that can reflect the characteristics of cathartic colon in humans, and serve as useful tools for further studies. PMID:33644192 | PMC:PMC7896687 | DOI:10.12998/wjcc.v9.i6.1251 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.