Cancers, Vol. 11, Pages 903: Diagnostic Leukapheresis Enables Reliable Transcriptomic Profiling of Single Circulating Tumor Cells to Characterize Inter-Cellular Heterogeneity in Terms of Endocrine Resistance Cancers doi: 10.3390/cancers11070903 Authors: Florian Reinhardt André Franken Franziska Meier-Stiegen Christiane Driemel Nikolas H. Stoecklein Johannes C. Fischer Dieter Niederacher Eugen Ruckhaeberle Tanja Fehm Hans Neubauer Circulating tumor cells (CTCs)...
Cancers, Vol. 11, Pages 902: The d16HER2 Splice Variant: A Friend or Foe of HER2-Positive Cancers? Cancers doi: 10.3390/cancers11070902 Authors: Lorenzo Castagnoli Michael Ladomery Elda Tagliabue Serenella M. Pupa Human epidermal growth factor receptor 2 (ERBB2 or HER2) amplification/overexpression is associated with a particularly aggressive molecular subtype of breast cancer (BC), characterized by a poor prognosis, increased metastatic potential, and disease recurrence. As...
Cancers, Vol. 11, Pages 900: miRNA Predictors of Pancreatic Cancer Chemotherapeutic Response: A Systematic Review and Meta-Analysis Cancers doi: 10.3390/cancers11070900 Authors: Madhav Madurantakam Royam Rithika Ramesh Ritika Shanker Shanthi Sabarimurugan Chellan Kumarasamy Nachimuthu Ramesh Kodiveri Muthukalianan Gothandam Siddharta Baxi Ajay Gupta Sunil Krishnan Rama Jayaraj Background: pancreatic cancer (PC) has increasing incidence and mortality in developing...
Cancers, Vol. 11, Pages 901: Clinical Translatability of “Identified” Circulating miRNAs for Diagnosing Breast Cancer: Overview and Update Cancers doi: 10.3390/cancers11070901 Authors: Grimaldi Incoronato The effective management of patients with breast cancer (BC) depends on the early diagnosis of the disease. Currently, BC diagnosis is based on diagnostic imaging and biopsy, while the use of non-invasive circulating biomarkers for diagnosis remains an unmet need. Among the plethora...
Cancers, Vol. 11, Pages 898: Circulating microRNAs as Promising Biomarkers in Colorectal Cancer Cancers doi: 10.3390/cancers11070898 Authors: Óscar Rapado-González Ana Álvarez-Castro Rafael López-López José Iglesias-Canle María Mercedes Suárez-Cunqueiro Laura Muinelo-Romay Colorectal cancer (CRC) is one of the most common cancers and a leading cause of cancer-related deaths worldwide. Despite numerous advances in therapeutic approaches, this cancer has a poor prognosis...
Cancers, Vol. 11, Pages 899: Store-Operated Ca2+ Entry in Tumor Progression: From Molecular Mechanisms to Clinical Implications Cancers doi: 10.3390/cancers11070899 Authors: Yih-Fung Chen Peng-Chan Lin Yu-Min Yeh Li-Hsien Chen Meng-Ru Shen The remodeling of Ca2+ homeostasis has been implicated as a critical event in driving malignant phenotypes, such as tumor cell proliferation, motility, and metastasis. Store-operated Ca2+ entry (SOCE) that is elicited by the depletion of...
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