Thursday, February 21, 2019

Prediction of Ligand Modulation Patterns on Membrane Receptors via Lysine Reactivity Profiling

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C9CC00520J, Communication
Ye Zhou, Zheyi Liu, Jinbao Zhang, Tongyi Dou, Jin Chen, Guang-Bo Ge, Shujia Zhu, Fangjun Wang
Herein we provide a mass spectrometry-based lysine reactivity profiling strategy to monitor the ligand modulation of protein receptors, which is achieved by active dimethyl labeling of lysine residues and comparison...
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