An automated platform for the enzyme-mediated assembly of complex oligosaccharides

An automated platform for the enzyme-mediated assembly of complex oligosaccharides

An automated platform for the enzyme-mediated assembly of complex oligosaccharides, Published online: 21 February 2019; doi:10.1038/s41557-019-0219-8

An automated platform that can synthesize a wide range of complex glycans could greatly facilitate progress in glycoscience. Now, a fully automated process for enzyme-mediated oligosaccharide synthesis has been developed. This process uses glycosyltransferase-catalysed reactions performed in solution, with product purification being accomplished by solid phase extraction using a sulfonate tag.

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