Wednesday, January 23, 2019

Benzyne-Mediated Trichloromethylation of Chiral Oxazolines

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C9CC00557A, Communication
Xin Huang, Weizhao Zhao, De-Li Chen, Yaling Zhan, Tingting Zeng, Huiquan Jin, Bo Peng
A three-component reaction bewteen benzyne, oxazolines and chloroform was developed for the synthesis of trichloromethyalted chiral oxazolidines. Benzyne not only serves as an electrophile towards oxazolines but also acts as...
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