B-cell acute lymphoblastic leukemia-related microRNAs: uncovering their diverse and special roles

xlomafota13 shared this article with you from Inoreader B-cell acute lymphoblastic leukemia-related microRNAs: uncovering their diverse and special roles Via American Journal of Cancer Research Am J Cancer Res. 2021 Apr 15;11(4):1104-1120. eCollection 2021. ABSTRACT B-cell acute lymphoblastic leukemia (B-ALL) is a common type of hematologic malignancy characterized by the uncontrolled growth of immature B lymphocytes. Genomics, transcriptomics, and proteomics at different levels contribute to early diagnosis and can thereby provide better treatment for cancer. MicroRNAs (miRNAs) are conducive to the diagnosis and treatment of patients with B-ALL. Moreover, evidence suggests that runaway miRNAs and exosomes containing miRNA may be involved in the occurrence of B-ALL, which can then be used as potential biomarkers. This review summarizes the role of miRNAs in the pathogenesis, diagnosis, prognosis, and treatment of B-ALL. PMID:33948348 | PMC:PMC8085864 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.