Neisseria gonorrhoeae and Chlamydia trachomatis are the 2 most commonly diagnosed and reported sexually transmitted infections in the United States.1 Among men, these infections cause urethritis and epididymitis. Among women, they cause cervicitis and urethritis, although most infected patients are asymptomatic.2 Antibiotics readily cure urethritis, cervicitis, and pelvic inflammatory disease, and early treatment of these infections prevents transmission and complications. All emergency department (ED) patients with presentations consistent with N gonorrhoeae or C trachomatis should undergo empirical therapy rather than test-based treatment.
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