Tuesday, April 20, 2021

Early postoperative serum albumin levels as predictors of surgical outcomes in head and neck squamous cell carcinoma

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Braz J Otorhinolaryngol. 2021 Apr 9:S1808-8694(21)00063-X. doi: 10.1016/j.bjorl.2021.03.004. Online ahead of print.

ABSTRACT

BACKGROUND: Malnutrition is a common issue in patients with head and neck squamous cell carcinoma and has a negative effect on surgical outcomes.

OBJECTIVE: We attempted to determine which malnutrition diagnostic variables can be used as predictors of postoperative complications in patients with head and neck squamous cell carcinoma.

METHODS: Forty-one patients undergoing surgery for head and neck squamous cell carcinoma were submitted to a prospective evaluation. Biochemical data, anthropometric measurements and evaluation of body composition were used in the nutritional analysis.

RESULTS: Twenty-two patients (53.6%) developed complications. Serum albumin measured on the first postoperative day was the only variable that significantly differed between groups. A cut-off value of 2.8 g/dL disting uished between patients with a complicated and uncomplicated postoperative course. Normalization of albumin levels occurred more frequently and more rapidly in the noncomplicated group.

CONCLUSION: Serum albumin measured on the first postoperative day was the only variable that was a predicter of postoperative complications after major head and neck squamous cell carcinoma surgery.

PMID:33875388 | DOI:10.1016/j.bjorl.2021.03.004

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