Wednesday, February 20, 2019

ROS-responsive and self-accelerating drug release nanoplatform for overcoming multidrug resistance

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C9CC00358D, Communication
Xueming Lv, Yiyong Zhu, Hamid Ghandehari, Ao Yu, Yongjian Wang
An 'on-demand' drug release and ROS-responsive nanoparticale was prepared by chemically conjugating hydrophobic α-tocopheryl succinate to hydrophilic poly(ethylene galycol) via thioketal linker. This nanoparticale encapsulated with doxorubicin and α-tocopheryl succinate...
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