Thursday, February 7, 2019

Non-reducible disulfide bond replacement implies that disulfide exchange is not required for hepcidin-ferroportin interaction

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C9CC00328B, Communication
Dong-Liang Huang, JingSi Bai, Meng Wu, Xia Wang, Bernd Riedl, Elisabeth Pook, Carsten Alt, Marion Erny, Yi-Ming Li, Donald Bierer, Jing Shi, Gemin Fang
Previous studies have led to opposing hypotheses about the requirement of intermolecular disulfide exchange in the binding of the iron regulatory peptide hepcidin to its receptor ferroportin. To clarify this...
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