Thursday, February 28, 2019

Facile preparation of functional cycloalkynes by an azide-to-cycloalkyne switching approach

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C9CC01113G, Communication
Suguru Yoshida, Tomoko Kuribara, Harumi Ito, Tomohiro Meguro, Yoshitake Nishiyama, Fumika Karaki, Yasutomo Hatakeyama, Yuka Koike, Isao Kii, Takamitsu Hosoya
A facile method for preparing various functional cycloalkynes, including proteins installed with a cycloalkyne moiety, from corresponding azides is developed. Treatment of diynes bearing strained and terminal alkyne moieties with...
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