Wednesday, January 30, 2019

Hydrophilic 18F-labeled trans-5-oxocene (oxoTCO) for efficient construction of PET agents with improved tumor-to-background ratios in neurotensin receptor (NTR) imaging

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C8CC09747J, Communication
Mengzhe Wang, Raghu Vannam, William Duane Lambert, Yixin Xie, Hui Wang, Benjamin Giglio, Xiaofen Ma, Zhanhong Wu, Joseph Fox, Zibo Li
Described here is an 18F-labeled trans-5-oxocene (oxoTCO) that through tetrazine ligation is used to construct a PET probe for neurotensin receptor (NTR) imaging. PET probe construction proceeds in 70% RCY...
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