ABSTRACT
Objectives
Covid-19 infection often causes olfactory dysfunction and parosmia may occur in some patients with olfactory dysfunction. In this study, we retrospectively investigated the effectiveness of modified olfactory training (MOT) for the treatment of Covid-19-induced parosmia.
Methods
This study presents results of MOT performed with 12 odors for 36 weeks in patients with olfactory dysfunction following Covid-19 infection. A total of 75 participants were included in the study (mean age 33 years, range 16–60 years). The patients were separated into two groups: 1) Treatment group consisted of parosmia patients who received MOT with three sets of four different odors sequentially. 2) Control group consisted of parosmia patients who did not perform any olfactory training. Both groups were matched for age and sex distribution of participants.
Results
When the treatment group and the control group were compared, a significant improvement was observed in both groups at the third, sixth, and ninth month, however the improvement in the treatment group was found to be better than in the control group (p<0.001). Extending the treatment from six to nine months in the treatment group was found to be effective in mitigating parosmia complaints and improving discrimination scores (p<0.001).
Conclusion
This study has shown that modified olfactory training is effective in the treatment of parosmia following Covid-19 infection.
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