Thursday, October 14, 2021

Pityriasis lichenoides-like drug reaction with numerous eosinophils

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Int J Clin Exp Pathol. 2021 Sep 15;14(9):1010-1012. eCollection 2021.

ABSTRACT

Pityriasis lichenoides-like drug reactions simulate pityriasis lichenoides clinically and histopathologically, though important differences exist. As a rule, pityriasis lichenoides has minimal to no eosinophils. However, this case illustrates that pityriasis lichenoides-like drug reaction can present with numerous eosinophils. This, in our experience is not rare, but contrasts with clinical reports in the literature that describe pityriasis lichenoides-like drug reactions with minimal to no eosinophils in the infiltrate. While similar, distinguishing these diseases is important given that pityriasis lichenoides is a lymphoproliferative disorder with a more protracted clinical course that is difficult to treat. We provide histopathological clues to aid in this important distinction.

PMID:34646420 | PMC:PMC8493263

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