Case 33-2021: A 68-Year-Old Man with Painful Mouth Ulcers
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A 68-year-old man was admitted with painful mouth ulcers and weight loss of 6 weeks' duration. The ulcers had worsened despite treatment with acyclovir, prednisone, and colchicine. The blood eosinophil count was increased, and the patient was positive for the HLA-B51 allele. A diagnostic procedure was performed.
Behçet's disease (BD) has been known to be strongly associated with the human leukocyte antigen (HLA) B51. This B51 association has been confirmed in many different ethnic groups between the Middle East and Japan, and it has been proposed that BD is prevalent in those ethnic groups along the old Silk Route.
Presentation of Case. Dr. Ian D. Cooley (Medicine): A 68-year-old man was admitted to this hospital because of painful mouth ulcers and weight loss. The patient had been well until 6 weeks before the current admission, when painful mouth ulcers and neck pain developed. He was evaluated at an urgent…
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