Tuesday, September 28, 2021

Morphological Changes in Nasal Mucosa in Patients with Sarcoidosis

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Abstract

•Changes in the microvascular network of the nasal mucosa may be accompanied by changes in olfaction.

•Contact endoscopic changes in the microvascular network of the nasal mucosa may be used as a marker of sinonasal sarcoidosis.

•A modified version of the Negoro's classification, in use for the tongue mucosa, may be used for the classification of contact endoscopic microvascular patterns of the nasal mucosa in patients with sarcoidosis

•The validation of the use of the vascular patterns of nasal mucosa on contact endoscopy as a marker of nasal disease activity is a major future research challenge

•Contact endoscopy emerges as a promising technique for on-site diagnosis of early, advanced or late inflammatory mucosal spots or generalized mucosal affection in sarcoidosis.

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