Subchondral bone as a novel target for regenerative therapy of osteochondritis dissecans: A case report

paythelady.612 shared this article with you from Inoreader Subchondral bone as a novel target for regenerative therapy of osteochondritis dissecans: A case report Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 May 26;9(15):3623-3630. doi: 10.12998/wjcc.v9.i15.3623. ABSTRACT BACKGROUND: Osteochondritis dissecans (OCD) is a rare disease of unclear cause characterized by subchondral bone damage and overlying cartilage defects. The current report presents the results of subchondral bone as a novel target for implantation of peripheral blood stem cells (PBSCs) in the treatment of OCD. CASE SUMMARY: A 16-year-old patient diagnosed with OCD underwent subchondral bone implantation of PBSCs. Four months later, the patient's visual analog scale scores, Western Ontario and McMaster University osteoarthritis index, and whole-organ magnetic resonance imaging score improved significantly, and regeneration of cartilage and subchondral bone was observed on magnetic resonance imaging. CONCLUSION: This is the first case of OCD treated with subchondral bone as an implantation target of PBSCs, which highlights the importance of subchondral bone for cartilage repair. This treatment could be a potential option for articular cartilage and subchondral bone recovery in OCD. PMID:34046461 | PMC:PMC8130072 | DOI:10.12998/wjcc.v9.i15.3623 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.