Friday, May 21, 2021

Parotid nuclear protein in testis midline carcinoma: a case report

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本文报道一例腮腺来源的睾丸核蛋白(nuclear protein in testis,NUT)中线癌患者,为35岁男性,因"发现右侧腮腺区肿物3年,增大2周"入院,行腮腺浅叶切除术,手术标本免疫组化及分子检测结果为NUT中线癌。患者术后接受放化疗联合靶向药物治疗,随访10个月内无疾病复发或其他不良事件。腮腺来源的NUT中线癌临床罕见,易发生误诊、漏诊,目前诊断方式依赖免疫组化(NUT抗体阳性)以及分子检测(NUT基因融合异位),其预后情况与患者年龄、融合基因类型、手术范围、术后放化疗方案以及靶向药物的使用相关,因此临床医生需警惕腮腺来源NUT中线癌的发生,尽量做到正确诊断、个性化治疗。.

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 May 7;56(5):510-513. doi: 10.3760/cma.j.cn115330-20201103-00853.

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PMID:34011009 | DOI:10.3760/cma.j.cn115330-20201103-00853

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