Tuesday, May 4, 2021

Intraventricular meningioma admixed with choroid plexus papilloma: a rare case report with review of literature

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Int J Clin Exp Pathol. 2021 Apr 15;14(4):545-550. eCollection 2021.

ABSTRACT

A 42-year-old male presented with a history of headaches for the previous 2 weeks. Magnetic resonance imaging of the brain showed a 3 cm-sized well-defined, enhancing mass in the atrium of the right lateral ventricle. The tumor comprised two heterogeneous components: approximately one-third of the tumor exhibited complex and delicate papillary fibrovascular cores lined with uniform cuboidal-to-columnar epithelial cells, whereas the remaining part was seen as a solid sheet comprising ovoid-to-spindle cells with plump cytoplasm, which occasionally had a whorling pattern. Further, immunohistochemical staining with cytokeratin 7 (CK7) and epithelial membrane antigen (EMA) clearly demarcated each component: the CK7+/EMA- choroid plexus papilloma and CK7-/EMA+ meningioma. This report provides a description of an unusual case of concomitant choroid plexus papilloma a nd ventricular meningioma presenting as a single mass, along with a review of relevant literature.

PMID:33936380 | PMC:PMC8085822

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