Wednesday, February 10, 2021

Sociodemographic and Survival Characteristics of 253 Human Papilloma Virus‐related Oropharyngeal Cancer Cases in Glasgow, Scotland – A retrospective analysis

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Abstract

Human Papilloma Virus (DNA)‐positive oropharyngeal cancer patients from more affluent areas have lower mortality compared to their socioeconomically deprived counterparts following adjustment for smoking, alcohol use, staging and treatment intent. This suggests that socioeconomic deprivation worsens survival even in Human Papilloma Virus (DNA)‐positive disease. Current world literature suggests that Human Papilloma Virus (DNA)‐positive oropharyngeal cancer patients present at a younger age and are more affluent, which is in contrast to this study, where patients present at an older age and have a lower socioeconomic background. Socioeconomic deprivation and high smoking rates may contribute towards poorer survival of oropharyngeal cancer in the West of Scotland. In contrast to findings from existing literature, this cohort of patients most frequently presented with neck adenopathy, rather than throat pain or ulceration. Late stage at presentation remains a common problem with oropharyngeal cancer patients in Scotland.

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