Thursday, October 22, 2020

Localized primary gastric amyloidosis: Three case reports.

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Localized primary gastric amyloidosis: Three case reports.

World J Clin Cases. 2020 Oct 06;8(19):4667-4675

Authors: Liu XM, Di LJ, Zhu JX, Wu XL, Li HP, Wu HC, Tuo BG

Abstract
BACKGROUND: Localized primary gastric amyloidosis is a rare disorder characterized by the extracellular deposition of insoluble fibrillary protein in the stomach and can mimic various diseases on endoscopic examination, including gastrointestinal stromal tumors, gastric cancer and ulcers.
CASE SUMMARIES: Here, we report a series of three cases of localized gastric amyloidosis mimicking gastric mucosa-associated lymphoid tissue (MALT) lymphoma on endoscopic examination that were evaluated over the past ten years in our hospital. The different detection times of this rare disease resulted in three completely different outcomes, indicating the strong importance of early detection, diagnosis and treatment. The difficulties encountered in making an accurate diagnosis and differential diagnosis are highlighted, and this report provides clinical experience for the diagnosis of localized primary gastric amyloidosis.
CONCLUSION: Localized gastric amyloidosis is a rare metabolic disease that resembles MALT lymphoma. Early detection, diagnosis and treatment of localized gastric amyloidosis result in an excellent prognosis.

PMID: 33083432 [PubMed]

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