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PathogensPathogens, Vol. 9, Pages 769: Effects o... MicroorganismsMicroorganisms, Vol. 8, Pages 143... Journal of Clinical MedicineJCM, Vol. 9, Pages 3... International Journal of Environmental Research... BiosensorsBiosensors, Vol. 10, Pages 128: Short... AntibioticsAntibiotics, Vol. 9, Pages 624: Prev... The New England Journal of Medicine: Search Resu... Journal of plastic, reconstructive & aesthetic ... Skull BaseSARS-CoV-2 Nasopharyngeal Swab Testin... pubmed: frontiers neuroscien...Wnt Signaling Reg... Head and NeckMiddle Cranial Fossa Approach to V... Rare CancersFetal Intrapericardial Teratomas: An... LarynxOutcomes of frontolateral vertical partial... Journal of Surgical EducationAnatomy by Whole Bo... Clinical TherapeuticsMedication-Based Refill Ad... Cancer/RadiothérapieIndex des auteursPublicatio... Alcohol and HomeostasisDownregulation of ROCK2 a... Oral and Maxillofacial SurgeryThe COVID-19 and ... Journal of Adolescent and Young Adult OncologyFe... Anti-Cancer Drugs - Current IssueActivation of ... Case Reports in MedicinePolymyxin B-Induced Ski... Latest Results for Sports MedicineEffects of Exe...
Retrospective single center analysis of outcome, risk factors and therapy in steroid refractory graft-versus-host disease after allogeneic hematopoietic cell transplantation.: Related ArticlesRetrospective single center analysis of outcome, risk factors and therapy in steroid refractory graft-versus-host disease after allogeneic hematopoietic cell transplantation.Bone Marrow Transplant. 2019 11;54(11):1805-1814Authors: Axt L, Naumann A, Toennies J, Haen SP, Vogel W, Schneidawind D, Wirths S, Moehle...
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Supporting migrants and refugees with posttraumatic stress disorder: development, pilot implementation, and pilot evaluation of a continuing interprofessional education for healthcare providers.: Related ArticlesSupporting migrants and refugees with posttraumatic stress disorder: development, pilot implementation, and pilot evaluation of a continuing interprofessional education for healthcare providers.BMC Med Educ. 2020 Sep 16;20(1):311Authors: Jobst S, Windeisen M, Wuensch A, Meng M, Kugler CAbstract...
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Laryngeal polyp associated with reflux disease: a case report.: Related ArticlesLaryngeal polyp associated with reflux disease: a case report.J Med Case Rep. 2020 Jan 04;14(1):2Authors: Hassan WAAbstract BACKGROUND: Among the most common benign laryngeal lesions are vocal nodules and polyps. Their etiology is related to vocal abuse. Gastroesophageal reflux disease is a common condition presenting with a broad spectrum of symptoms, among which are extraesophageal manifestations such as...
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Relationship between Snoring and Lifestyle-related Diseases among a Japanese Occupational Population.: Related ArticlesRelationship between Snoring and Lifestyle-related Diseases among a Japanese Occupational Population.Intern Med. 2020;59(18):2221-2228Authors: Sekizuka H, Miyake HAbstract Objective Snoring is a common physical condition in active workers. However, the link between snoring and health problems is poorly understood. Therefore, the prevalence of snoring in Japanese workers...
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Giant cell-rich extrapleural solitary fibrous tumor: Cytological findings and differential diagnosis of a rare neoplasm.: Related ArticlesGiant cell-rich extrapleural solitary fibrous tumor: Cytological findings and differential diagnosis of a rare neoplasm.Diagn Cytopathol. 2020 Sep 17;:Authors: Ronchi A, Cozzolino I, Montella M, Donadio A, Motta G, Franco R, Palombini LAbstract Extrapleural solitary fibrous tumor (ESFT) is a rare neoplasm with a variable biological behavior that may occur...
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Malignant tumors in hernia sac: Clinicopathological and immunohistochemical studies of 21 cases at a single institution.: Related ArticlesMalignant tumors in hernia sac: Clinicopathological and immunohistochemical studies of 21 cases at a single institution.Pathol Int. 2020 Sep 17;:Authors: Zhang D, Yang Q, Katerji R, Drage MG, Huber A, Liao XAbstract Malignant tumors presented in hernia sac are very rare and the clinicopathological features are not well studied. We retrospectively reviewed...
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Papillary-Cystic Neoplasms of the Middle Ear Are Distinct From Endolymphatic Sac Tumors.: Related ArticlesPapillary-Cystic Neoplasms of the Middle Ear Are Distinct From Endolymphatic Sac Tumors.Histopathology. 2020 Sep 17;:Authors: Taverna C, Pollastri F, Pecci R, Giannoni B, Fattorini C, Santucci M, Mueller SK, Stoehr R, Franchi A, Agaimy AAbstract AIMS: Papillary neoplasms of the middle and inner ear are rare and poorly characterized. The current WHO classification lumped them into two...
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TMP3-NTRK1 rearranged uterine sarcoma: A case report.: Related ArticlesTMP3-NTRK1 rearranged uterine sarcoma: A case report.Case Rep Womens Health. 2020 Oct;28:e00246Authors: Boyle W, Williams A, Sundar S, Yap J, Taniere P, Rehal P, Ganesan RAbstract Introduction: Uterine sarcomas are a group of rare tumours with heterogeneous morphological and genetic features. Recent advances in the molecular characterisation of these tumours have identified a novel clinicopathological category underpinned...
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Pediatric Suprasellar Germ Cell Tumors: A Clinical and Radiographic Review of Solitary vs. Bifocal Tumors and Its Therapeutic Implications.: Related ArticlesPediatric Suprasellar Germ Cell Tumors: A Clinical and Radiographic Review of Solitary vs. Bifocal Tumors and Its Therapeutic Implications.Cancers (Basel). 2020 Sep 14;12(9):Authors: Esfahani DR, Alden T, DiPatri A, Xi G, Goldman S, Tomita TAbstract Suprasellar germ cell tumors (S-GCTs) are rare, presenting in either solitary or multifocal...
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[Penile angiomyxoma: a case report].: Related Articles[Penile angiomyxoma: a case report].Urologiia. 2020 Sep;(4):100-103Authors: Yarin GY, Fedorenko VN, Vilgelmi IA, Ageeva TA, Voronina EIAbstract Angiomyxoma is a rare benign tumor prone to aggressive and invasive growth and relapse. Very few case reports of tumors with this morphology have been published in the world literature. In this paper, we report a rare case of penile angiomyxoma, which illustrates that any preoperative examination...
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[Colorectal non-invasive epithelial lesions: conception of conventional adenoma and diagnosis of rare subtypes].: Related Articles[Colorectal non-invasive epithelial lesions: conception of conventional adenoma and diagnosis of rare subtypes].Zhonghua Bing Li Xue Za Zhi. 2020 Sep 08;49(9):962-967Authors: Li J, Teng XD, Lai MDPMID: 32892572 [PubMed - indexed for MEDLINE]结直肠非浸润性上皮性病变：普通型腺瘤相关概念介绍和少见细胞亚型的诊断李君滕晓东来茂德中华病理学杂志, 2020,49(09) : 962-967. DOI: 10.3760/cma.j.cn112151-20200316-00210摘要结直肠腺瘤是最常见的肠道病变，典型的腺瘤诊断相对简单，但少数腺瘤可以出现黏液/杯状细胞为主、潘氏细胞成分、神经内分泌细胞增生、鳞状体形成、透明细胞化生、嗜酸细胞化生或印戒细胞癌成分等病理改变，以及出现上皮错位或累及淋巴腺复合体等相对复杂情况，这些对腺瘤的诊断造成一定的困扰。作者梳理和归纳结直肠腺瘤相关的基本概念，并通过典型病例分析总结上述少见病变的诊断要点、鉴别诊断及临床病理意义。引用本文: 李君,...
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Metastatic large cell neuroendocrine lung cancer to the foramen magnum: A case report.: Related ArticlesMetastatic large cell neuroendocrine lung cancer to the foramen magnum: A case report.Medicine (Baltimore). 2020 Aug 14;99(33):e21628Authors: Zou P, Liu J, Cheng G, Wang K, Li A, Li S, Wang Y, Zou X, Ji X, Gao D, Liu W, Jiang XAbstract RATIONABLE: Large cell neuroendocrine carcinoma of the lung is rare, especially in the area of the foramen magnum. No previous studies have reported metastatic...
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Multiple schwannoma of the seminal vesicle: A case report.: Related ArticlesMultiple schwannoma of the seminal vesicle: A case report.Medicine (Baltimore). 2020 Aug 14;99(33):e21603Authors: Zhang Y, Zhao J, Xu P, Qi QAbstract RATIONALE: Schwannomas of the seminal vesicles are extremely rare, and only cases of single seminal vesicle schwannomas have been reported. Here, we report a case of multiple schwannoma of the seminal vesicle. PATIENT CONCERNS: We report a rare case of multiple...
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Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: A case report.: Related ArticlesThyroid-like low-grade nasopharyngeal papillary adenocarcinoma: A case report.Medicine (Baltimore). 2020 Aug 14;99(33):e21599Authors: Maocai L, Fuxing L, Lianqing L, Lili G, WenChao D, ShouZhou LAbstract INTRODUCTION: Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma (TL-LGNPPA) is a rare neoplasm characterized by morphological analogy to papillary thyroid carcinoma and the abnormal...
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HER2-positive pure mucinous breast carcinoma: A case report and literature review.: Related ArticlesHER2-positive pure mucinous breast carcinoma: A case report and literature review.Medicine (Baltimore). 2020 Aug 14;99(33):e20996Authors: Zhao X, Yang X, Gao R, Zhai L, Yang L, Yu KAbstract INTRODUCTION: Pure mucinous carcinoma is a rare type of breast carcinoma, but it usually has a favorable prognosis. Tumors of pure mucinous carcinoma are typically positive for both estrogen receptor...
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[Resection of retroperitoneal leiomyosarcoma followed by replacement of cavarenal segment of inferior vena cava].: Related Articles[Resection of retroperitoneal leiomyosarcoma followed by replacement of cavarenal segment of inferior vena cava].Khirurgiia (Mosk). 2020;(8):110-116Authors: Ryabov AB, Khomyakov VM, Cheremisov VV, Kostrygin AK, Aksenov SA, Pestin ISAbstract The authors reported a rare clinical case of successful surgical treatment of young female with retroperitoneal leiomyosarcoma...
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[Solitary fibrous tumor of pleura (symptoms, diagnosis, treatment)].: Related Articles[Solitary fibrous tumor of pleura (symptoms, diagnosis, treatment)].Khirurgiia (Mosk). 2020;(8):35-41Authors: Salimov ZM, Pikin OV, Ryabov AB, Popov MI, Kononets PV, Volchenko NN, Blinov DA, Nikulin KAAbstract OBJECTIVE: Optimization of diagnosis and treatment of patients with solitary fibrous tumor of pleura, analysis of overall survival and disease-free survival, predictors of recurrence. MATERIAL...
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Wnt activation as a therapeutic strategy in medulloblastoma.: Related ArticlesWnt activation as a therapeutic strategy in medulloblastoma.Nat Commun. 2020 08 28;11(1):4323Authors: Manoranjan B, Venugopal C, Bakhshinyan D, Adile AA, Richards L, Kameda-Smith MM, Whitley O, Dvorkin-Gheva A, Subapanditha M, Savage N, Tatari N, McKenna D, Bassey-Archibong B, Winegarden N, Hallett R, Provias JP, Yarascavitch B, Ajani O, Fleming A, Bader GD, Pugh TJ, Doble BW, Singh SKAbstract Medulloblastoma...
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[Transverse myelitis syndrom as a result of neuromyelitis optica spectrum disorders, systemic lupus erythematosus and myasthenia gravis combination].: Related Articles[Transverse myelitis syndrom as a result of neuromyelitis optica spectrum disorders, systemic lupus erythematosus and myasthenia gravis combination].Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(7. Vyp. 2):97-106Authors: Topuzova MP, Bisaga GN, Alekseeva TM, Isabekova PS, Сhaykovskaya AD, Panina EB, Pavlova TA, Ternovykh IKAbstract...
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[Retroauricular teratoma with congenital microtia and ankylotia: a case report].: Related Articles[Retroauricular teratoma with congenital microtia and ankylotia: a case report].Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Apr;34(4):372-373Authors: Shi S, Liang H, Xu L, Zhang Y, Fan Z, Tian Y, Wang CAbstract Teratoma is a germ cell tumor, which is rare behind the ear. We described a rare case of retroauricular teratoma accompanied with congenital malformation of external and middle...
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[Renomedullary interstitial cell tumor: review of a rare clinical case].: Related Articles[Renomedullary interstitial cell tumor: review of a rare clinical case].Urologiia. 2020 Jun;(3):91-93Authors: Todorov SS, Kogan MI, Deribas VY, Kazmin ASAbstract Autopsy study of a 49-year-old patient demonstrates a rare kidney tumor that had a structure of a mesenchymal renomedullary interstitial tumor (RIO), which had specific characteristics. They include a predominance of the cellular component...
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Focus on the pulmonary involvement and genetic patterns in Birt-Hogg-Dubè syndrome: Literature review.: Related ArticlesFocus on the pulmonary involvement and genetic patterns in Birt-Hogg-Dubè syndrome: Literature review.Respir Med. 2020 07;168:105995Authors: Marziali V, Geropoulos G, Frasca L, Longo F, Patrini D, Panagiotopoulos N, Crucitti PAbstract INTRODUCTION: Brit-Hogg-Dubé syndrome (BHD) is a rare disorder that is estimated to affects about 600 families in the World. The disease-causing...
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Natural history of incidental sporadic and tuberous sclerosis complex associated lymphangioleiomyomatosis.: Related ArticlesNatural history of incidental sporadic and tuberous sclerosis complex associated lymphangioleiomyomatosis.Respir Med. 2020 07;168:105993Authors: Di Marco F, Terraneo S, Dias OM, Imeri G, Centanni S, Rinaldo RF, Giuliani L, Lesma E, Palumbo G, Wanderley M, Ribeiro Carvalho CR, Guedes Baldi BAbstract Lymphangioleiomyiomatosis (LAM) is a rare disease affecting women in...
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Spinal metastasis of glioblastoma multiforme before gliosarcomatous transformation: a case report.: Related ArticlesSpinal metastasis of glioblastoma multiforme before gliosarcomatous transformation: a case report.BMC Neurol. 2020 May 11;20(1):178Authors: Hsu BH, Lee WH, Yang ST, Han CT, Tseng YYAbstract BACKGROUND: Glioblastoma multiforme (GBM) is one of the most aggressive malignant brain tumors. Intracranial GBM metastases to the spine are rarely detected clinically. Secondary gliosarcomas...
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Mediastinal 99mTc-Methylene Diphosphonate Accumulation in a Patient With Primary Mediastinal Soft Tissue Giant Cell Tumor.: Related ArticlesMediastinal 99mTc-Methylene Diphosphonate Accumulation in a Patient With Primary Mediastinal Soft Tissue Giant Cell Tumor.Clin Nucl Med. 2020 Jun;45(6):477-479Authors: Chen H, Fan Q, Su MAbstract Soft tissue giant cell tumor (GCT) is rare. It usually involves the extremities. We report the case of a 37-year-old woman who was suspected of having mediastinal...
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Primary Neuroendocrine Tumor of the Ileostomy Stoma on 68Ga-DOTATATE PET/CT.: Related ArticlesPrimary Neuroendocrine Tumor of the Ileostomy Stoma on 68Ga-DOTATATE PET/CT.Clin Nucl Med. 2020 Jun;45(6):463-464Authors: Yu L, Braun A, Hansen NJ, Downey RT, Johnson CMAbstract A 75-year-old man presented with bleeding ileostomy stoma 20 years after total colectomy and end ileostomy for chronic ulcerative colitis. On physical examination, the stoma was mass-like and firm with friable mucosa. Wedge...
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Primary Pancreatic Yolk Sac Tumor Presenting as Diffusely Enlarged Pancreas in Initial 18F-FDG PET/CT.: Related ArticlesPrimary Pancreatic Yolk Sac Tumor Presenting as Diffusely Enlarged Pancreas in Initial 18F-FDG PET/CT.Clin Nucl Med. 2020 Jun;45(6):483-486Authors: Sui H, Zhu Z, Li Z, Luo YAbstract Yolk sac tumor is a rare and highly malignant germ cell tumor. We report a case of yolk sac tumor primarily in the pancreas in a 32-year-old man. He presented with pancreatitis at presentation...
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Renal Medullary Carcinoma on Dual-Time Point FDG PET/CT Imaging.: Related ArticlesRenal Medullary Carcinoma on Dual-Time Point FDG PET/CT Imaging.Clin Nucl Med. 2020 Jun;45(6):446-447Authors: Hou G, Jiang Y, Wang J, Li F, Cheng WAbstract Renal medullary carcinoma is a rare and highly aggressive tumor seen almost exclusively in young individuals of African descent with sickle cell disease. Here, we describe a case of a 29-year-old man, who did not have sickle cell disease, with pathologically...
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Colon Adenocarcinoma Associated With Clostridium Septicum Endophthalmitis Detected on 18F-FDG PET/CT.: Related ArticlesColon Adenocarcinoma Associated With Clostridium Septicum Endophthalmitis Detected on 18F-FDG PET/CT.Clin Nucl Med. 2020 Jun;45(6):459-460Authors: Plouznikoff N, Artigas C, Woff E, Ene D, Flamen PAbstract Endogenous Clostridium septicum endophthalmitis is a rare and fulminant ocular infection, usually encountered in immunocompromised or diabetic patients. It is also highly...
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High rate of profound clonal and renal responses with daratumumab treatment in heavily pre-treated patients with light chain (AL) amyloidosis and high bone marrow plasma cell infiltrate.: Related ArticlesHigh rate of profound clonal and renal responses with daratumumab treatment in heavily pre-treated patients with light chain (AL) amyloidosis and high bone marrow plasma cell infiltrate.Am J Hematol. 2020 08;95(8):900-905Authors: Milani P, Fazio F, Basset M, Berno T, Larocca A, Foli A, Riva M,...
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Parathyroid Carcinoma Shown on 99mTc-Sestamibi Parathyroid SPECT/CT Scan in a Pediatric Patient.: Related ArticlesParathyroid Carcinoma Shown on 99mTc-Sestamibi Parathyroid SPECT/CT Scan in a Pediatric Patient.Clin Nucl Med. 2020 Jun;45(6):480-482Authors: Wang W, Liu J, Liu J, Yang JAbstract A 10-year-old boy presented with back pain. Tc-methylene diphosphonate bone scan demonstrated the sign of metabolic bone disease, suspected due to hyperparathyroidism. Tc-sestamibi parathyroid SPECT/CT...
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A knee stiffness unusual etiology.: Related ArticlesA knee stiffness unusual etiology.Tunis Med. 2019 Nov;97(11):1307-1310Authors: Zitouna K, Riahi H, Zheni A, Rekik S, Arfa W, Barsaoui MAbstract Progressive unilateral knee stiffness is an uncommon complaint in older adult. Tumor and specific infection should be considered in addition to osteoarthritis. We report a case of intracapsular and paraarticular chondroma in the infrapatellar Hoffa's fat pad that presented as a painless limited...
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Diffuse Metastases in Bilateral Penile Corpus Cavernosum From Renal Cancer Diagnosed by 18F-FDG PET/CT.: Related ArticlesDiffuse Metastases in Bilateral Penile Corpus Cavernosum From Renal Cancer Diagnosed by 18F-FDG PET/CT.Clin Nucl Med. 2020 Jun;45(6):451-452Authors: Zou Q, Jiao J, Zou MH, Yang T, Zhang YAbstract We report a rare case of a 60-year-old man with diffuse metastases in bilateral penile corpus cavernosum after radical nephrectomy for left renal carcinoma. F-FDG PET/CT demonstrated...
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Splenogonadal Fusion in Children: A Rare Entity Mimicking Inguinal Tumor.: Related ArticlesGonadal tissues include germ cells, cells from the sex cord, and gonadal stromal cells. [ ] Neoplasms composed of tissues of the OVARY or the TESTIS, not neoplasms located in the ovaries or testes. Gonadal tissues include GERM CELLS, cells from the sex cord, and gonadal stromal cells. [gonadal tissue neoplasmSplenogonadal Fusion in Children: A Rare Entity Mimicking Inguinal Tumor.Clin Nucl Med. 2020 Jun;45(6):453-454Authors:...
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Rituximab for acute demyelinating myelopathy after allogeneic hematopoietic stem cell transplantation: a case report.: Related ArticlesRituximab for acute demyelinating myelopathy after allogeneic hematopoietic stem cell transplantation: a case report.Postgrad Med. 2020 Jun;132(5):485-488Authors: Xing L, Wen S, Niu Z, Wang F, Zhang XAbstract Acute demyelinating myelopathy after allogeneic hematopoietic stem cell transplantation (HSCT) is rare, and the exact pathogenesis remains unclear....
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[Diseases of the Lacrimal Gland].: Related Articles[Diseases of the Lacrimal Gland].Klin Monbl Augenheilkd. 2020 May;237(5):703-723Authors: Schittkowski MP, Storch MWAbstract Tear gland diseases are comparatively rare in daily ophthalmological practice. The aim of this article is on the one hand to present the necessary basic knowledge and on the other hand to draw a bow to important current publications on the subject in order to provide the reader with sufficient knowledge for daily practice...
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Clinical Manifestations, Diagnosis, and Management of First Branchial Cleft Fistula/Sinus: A Case Series and Literature Review.: Related ArticlesClinical Manifestations, Diagnosis, and Management of First Branchial Cleft Fistula/Sinus: A Case Series and Literature Review.J Oral Maxillofac Surg. 2020 May;78(5):749-761Authors: Liu H, Cheng A, Ward BB, Wang C, Han Z, Feng ZAbstract PURPOSE: First branchial cleft fistula/sinus is a rare congenital developmental deformity that can sometimes...
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A rare association between true thymic hyperplasia and thyroid follicular tumor: a case report.: Related ArticlesA rare association between true thymic hyperplasia and thyroid follicular tumor: a case report.J Med Case Rep. 2020 Jan 15;14(1):9Authors: Kiwaki T, Tanaka H, Akiyama Y, Akaki M, Tomita M, Kataoka HAbstract BACKGROUND: True thymic hyperplasia is a rare condition characterized by enlargement of the thymus while its normal structure is retained. True thymic hyperplasia is known...
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Occurrence of abscesses during treatment with pazopanib in metastatic renal cancer: a case report.: Related ArticlesOccurrence of abscesses during treatment with pazopanib in metastatic renal cancer: a case report.J Med Case Rep. 2020 Jan 11;14(1):7Authors: Puliafito I, Russo A, Sciacca D, Puglisi C, Giuffrida DAbstract BACKGROUND: Pazopanib is a multitarget tyrosine kinase inhibitor used in the treatment of renal cancer and soft tissue sarcoma. Its use is commonly associated with a number...
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Merkel Cell Carcinoma of the Head and Neck Compared to Other Anatomical Sites in a Real-World Setting: Importance of Surgical Therapy for Facial Tumors.: Related ArticlesMerkel Cell Carcinoma of the Head and Neck Compared to Other Anatomical Sites in a Real-World Setting: Importance of Surgical Therapy for Facial Tumors.Facial Plast Surg. 2020 Jun;36(3):249-254Authors: Kirchberger MC, Heppt MV, Schuler G, Berking C, Heinzerling LAbstract Merkel cell carcinoma (MCC) is a rare and aggressive...
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Unexpected vincristine-induced systemic capillary leak syndrome in patients with Wilm's tumor: A single institution experience.: Related ArticlesUnexpected vincristine-induced systemic capillary leak syndrome in patients with Wilm's tumor: A single institution experience.Pediatr Hematol Oncol. 2020 Feb;37(1):90-96Authors: Zhang YT, Zhang L, Yao YM, Zhong XD, Chang JAbstract Capillary leak syndrome (CLS) is a rare but fatal disease, which has been reported following the infusions of interleukin-2,...
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Outcomes of treatment of mammary analogue secretory carcinoma of the parotid gland.: Related ArticlesOutcomes of treatment of mammary analogue secretory carcinoma of the parotid gland.Br J Oral Maxillofac Surg. 2020 02;58(2):158-162Authors: Lee DH, Kim JH, Yoon TM, Lee JK, Lim SCAbstract Mammary analogue secretory carcinoma (MASC) of the salivary gland is a newly-described, rare, malignant tumour. Few patients present with MASC of the parotid gland, so the exact characteristics, outcomes...
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Castleman Disease of the Parotid Gland: A Case Report.: Related ArticlesCastleman Disease of the Parotid Gland: A Case Report.J Oral Maxillofac Surg. 2020 Mar;78(3):400.e1-400.e6Authors: Xiao-Dong L, Qiu-Xu W, Wei-Xian LAbstract Castleman disease is a rare lymphoproliferative disorder characterized by the formation of painless hyperplastic lymph nodes. It can affect any lymph nodes of the body but rarely affects the salivary gland. We describe a patient with unicentric Castleman disease...
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[Pheochromocytomatosis after adrenalectomy: metastasis or cell seeding?]: Related Articles[Pheochromocytomatosis after adrenalectomy: metastasis or cell seeding?]Chirurg. 2020 Apr;91(4):345-353Authors: Weber F, Belker J, Unger N, Lahner H, Theurer S, Schmid KW, Führer D, Dralle HAbstract Pheochromocytomatosis is defined as a multifocal cell dissemination limited to the operatively opened space with no signs of distant metastasis. After primary adrenalectomy due to a pheochromocytoma this...
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Storiform collagenoma (sclerotic fibroma) of the oral mucosa.: Related ArticlesStoriform collagenoma (sclerotic fibroma) of the oral mucosa.Br J Oral Maxillofac Surg. 2020 02;58(2):231-233Authors: Elledge R, Nandra B, Bates T, Zardo D, Parmar SAbstract Storiform collagenoma (also called sclerotic fibroma) is uncommon, occurs as a cutaneous fibrous neoplasm, and is particularly rare in mucosal tissue in the head and neck. We describe an unexpected diagnosis in the oral cavity. Histopathological...
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Pediatric myeloid sarcoma: a single institution clinicopathologic and molecular analysis.: Related ArticlesPediatric myeloid sarcoma: a single institution clinicopathologic and molecular analysis.Pediatr Hematol Oncol. 2020 Feb;37(1):76-89Authors: Zhou T, Bloomquist MS, Ferguson LS, Reuther J, Marcogliese AN, Elghetany MT, Roy A, Rao PH, Lopez-Terrada DH, Redell MS, Punia JN, Curry CV, Fisher KEAbstract Myeloid sarcoma (MS) is a neoplastic condition composed of immature myeloid cells involving...
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Images of the month 2: A rare case of haematemesis from a gastric submucosal lesion.: Related ArticlesImages of the month 2: A rare case of haematemesis from a gastric submucosal lesion.Clin Med (Lond). 2019 09;19(5):414-415Authors: Hashim A, Afzal Z, Ryan S, Dubois PPMID: 31530694 [PubMed - indexed for MEDLINE]Clin Med (Lond). 2019 Sep; 19(5): 414–415.doi: 10.7861/clinmed.2019-0184PMCID: PMC6771355PMID: 31530694Images of the month 2: A rare case of haematemesis from a gastric submucosal lesionAhmed...
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Nasal Sebaceous Carcinoma: A Case Report and Review of the Literature.: Related ArticlesNasal Sebaceous Carcinoma: A Case Report and Review of the Literature.J Oral Maxillofac Surg. 2020 Jan;78(1):82-86Authors: Kholaki O, Chang D, Kim RYAbstract Sebaceous carcinoma arising from the nasal vestibule is exceedingly rare, with 3 cases previously reported. We have described the case of a 69-year-old man with an indolent exophytic growth on the medial aspect of his right nasal vestibule. Incisional...
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Mixed epithelial and stromal tumor after pediatric kidney transplant.: Related ArticlesMixed epithelial and stromal tumor after pediatric kidney transplant.Pediatr Transplant. 2019 12;23(8):e13575Authors: Ferdjallah A, Gordon P, Kirankumar V, Dietz K, Bu L, Verghese PAbstract MEST of the kidney are a benign group of tumors with very rare incidence of malignant transformation. First described in 1998, this tumor has never been reported in a transplanted organ before. We present a unique...
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Metastatic epithelioid haemangioendothelioma masquerading as periodontal pathosis: a case report.: Related ArticlesWhat is periapical Pathosis?Pulpal pathosis is diagnosed as reversible pulpitis, irreversible pulpitis (asymptomatic), irreversible pulpitis (symptomatic), and pulp necrosis. ... 8 Apical periodontitis is a pathological change of the periapical tissue that frequently develops as a consequence of irreversible pulpitis.Pulp and periapical pathosis | Request PDF - ResearchGateMetastatic...
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Skin-directed radiation therapy for cutaneous lymphoma: The Mayo Clinic experience.: Related ArticlesSkin-directed radiation therapy for cutaneous lymphoma: The Mayo Clinic experience.J Am Acad Dermatol. 2020 Mar;82(3):634-641Authors: King BJ, Lester SC, Tolkachjov SN, Davis MDP, Gibson LE, Martenson JAAbstract BACKGROUND: Focal or total skin radiation therapy can be used to treat mild to refractory cutaneous T-cell lymphoma. OBJECTIVE: To report the broad therapeutic benefit of...
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Rituximab-induced serum sickness is more frequent in autoimmune diseases as compared to hematological malignancies: A French nationwide study.: Related ArticlesRituximab-induced serum sickness is more frequent in autoimmune diseases as compared to hematological malignancies: A French nationwide study.Eur J Intern Med. 2019 Sep;67:59-64Authors: Bayer G, Agier MS, Lioger B, Lepelley M, Zenut M, Lanoue MC, Maillot F, Jonville-Bera APAbstract INTRODUCTION: Rituximab induced serum sickness (RISS)...
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Cytotoxic T Cells and their Activation Status are Independent Prognostic Markers in Meningiomas.: Related ArticlesCytotoxic T Cells and their Activation Status are Independent Prognostic Markers in Meningiomas.Clin Cancer Res. 2019 09 01;25(17):5260-5270Authors: Rapp C, Dettling S, Liu F, Ull AT, Warta R, Jungk C, Roesch S, Mock A, Sahm F, Schmidt M, Jungwirth G, Zweckberger K, Lamszus K, Gousias K, Kessler AF, Grabe N, Loehr M, Ketter R, Urbschat S, Senft C, Westphal M, Abdollahi A, Debus J, von...
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Paraneoplastic movement disorders: phenomenology, diagnosis, and treatment.: Related ArticlesParaneoplastic movement disorders: phenomenology, diagnosis, and treatment.Eur J Intern Med. 2019 Sep;67:14-23Authors: Chirra M, Marsili L, Gallerini S, Keeling EG, Marconi R, Colosimo CAbstract Paraneoplastic syndromes include, by definition, any symptomatic and non-metastatic condition associated with a neoplasm. Paraneoplastic movement disorders are a heterogeneous group of syndromes encompassing...
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The expression and clinical significance of an Epithelial‐Mesenchymal Transition inducer, SNAI1, in head and neck carcinoma: AbstractBackgroundSNAI1 is an Epithelial‐Mesenchymal Transition (EMT) inducer, which has been indicated to play a role in the progression of cancers. We aimed to evaluate the expression and prognostic roles of SNAI1 in head and neck carcinoma (HNC).MethodsThe study involved two major phases. In the in silico phase, the SNAI1 expression and its association with clinical features...
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Stokes polarimetry-based second harmonic generation microscopy for collagen and skeletal muscle fiber characterization: AbstractThe complete polarization state of second harmonic (SH) light was measured and characterized by collagen type I and skeletal muscle fiber using a Stokes vector-based SHG microscope. The polarization states of the SH signal are analyzed in a pixel-by-pixel manner and displayed through two dimensional (2D) Stokes vector images. Various polarization parameters are reconstructed...
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Robotic surgery for gastric cancer in the West: a systematic review and meta-analyses of short-and long-term outcomes.: Related ArticlesRobotic surgery for gastric cancer in the West: a systematic review and meta-analyses of short-and long-term outcomes.Int J Surg. 2020 Sep 14;:Authors: Solaini L, Avanzolini A, Pacilio CA, Cucchetti A, Cavaliere D, Ercolani GAbstract BACKGROUND: This review aims to merge all the western studies dealing with robotic gastrectomies (RG) to provide pooled results...
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Semiautomatic morphometric analysis of skeletal muscle obtained by needle biopsy in older adults: AbstractAnalysis of skeletal muscle mass and composition is essential for studying the biology of age-related sarcopenia, loss of muscle mass, and function. Muscle immunohistochemistry (IHC) allows for simultaneous visualization of morphological characteristics and determination of fiber type composition. The information gleaned from myosin heavy chain (MHC) isoform, and morphological measurements offer...
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The role of the tumour microenvironment in the angiogenesis of pituitary tumours: AbstractPurposeAngiogenesis has been studied in pituitary neuroendocrine tumours (PitNETs), but the role of the tumour microenvironment (TME) in regulating PitNET angiogenesis remains unknown. We aimed to characterise the role of TME components in determining the angiogenetic PitNET profile, focusing on immune cells and tumour-derived cytokines. MethodsImmune cells were studied by immunohistochemistry...
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Evaluation of the interrater and intermethod agreement of the German multiparametric ultrasound criteria for the grading of internal carotid artery stenosis: AbstractPurposeThe interdisciplinary German guidelines for the diagnosis and treatment of internal carotid artery stenosis (ICAS) recommend a multiparametric approach for the sonographic grading of extracranial ICAS. The aim of this study is to evaluate the interrater and intermethod agreement of this elaborated sonographic approach with different...
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Simultaneous time of flight-MRA and T2* imaging for cerebrovascular MRI: AbstractPurpose3D multi-echo gradient-recalled echo (ME-GRE) can simultaneously generate time-of-flight magnetic resonance angiography (pTOF) in addition to T2*-based susceptibility-weighted images (SWI). We assessed the clinical performance of pTOF generated from a 3D ME-GRE acquisition compared with conventional TOF-MRA (cTOF). MethodsEighty consecutive children were retrospectively identified who obtained...
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Diagnostic value of exosomal circMYC in radioresistant nasopharyngeal carcinoma: AbstractBackgroundThe relationship between circulating exosomal circular RNA (circRNA) and prognosis of patients with nasopharyngeal carcinoma (NPC) remain unknown. This study focused on the expression of exosomal circMYC and its relationship with the recurrence and prognosis of patients with NPC.MethodsThe circulating exosomes were obtained from 210 patients with NPC. Quantitative polymerase chain reaction, 5‐ethynyl‐2′‐deoxyuridine...
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Middle Cranial Fossa Approach to Vestibular Schwannoma Resection in the Older Patient Population: Objective: Compare outcomes of middle cranial fossa approach (MCF) to vestibular schwannoma (VS) resection in patients 60 years of age and older to patients under 60. Study Design: Retrospective case series. Setting: Tertiary referral center. Patients: Charts of 216 consecutive VS patients over 18 years of age were reviewed to identify 67 patients who underwent MCF approach to VS resection...
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Transimpedance Matrix (TIM) Measurement for the Detection of Intraoperative Electrode Tip Foldover Using the Slim Modiolar Electrode: A Proof of Concept Study: Objectives: The aim of this study is to report on our preliminary experience with Transimpedance Matrix (TIM)-measurement for the detection of cochlear implant electrode tip foldovers compared with intraoperative imaging in patients implanted with the slim modiolar electrode (SME). Study Design: Proof of concept study. Setting: ...
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Cochlear Implantation in Cases of Inner Ear Malformation: A Novel and Simple Grading, Intracochlear EABR, and Outcomes of Hearing: Objective: To propose a simple grading of inner ear malformation (IEM) and investigate intracochlear electrical auditory brainstem response (EABR) and outcomes for hearing in terms of the novel grading system. Study Design: Retrospective case review. Setting: Tertiary referral center. Patients: Sixty patients with IEMs who received cochlear implants....
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Perilymphatic Fistula: Consideration Based on MRI and Surgery: No abstract available
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Patency of Anterior Epitympanic Space and Surgical Outcomes After Endoscopic Ear Surgery for the Attic Cholesteatoma: Objective: To reveal the patency of the anterior epitympanic space (AES) and the surgical outcomes after transcanal endoscopic ear surgery (TEES) for attic cholesteatoma with a classification of anatomical variation of the AES. Study Design: Retrospective case review. Setting: Tertiary referral center. Patients: Seventy-four ears (72 patients with early-stage (I...
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Investigating the Electrical Properties of Different Cochlear Implants: Aim: This study characterises and compares electrical properties and current spread across four different makes of cochlear implants with differing electrode designs using a 3D-printed artificial cochlear model. Background: Cochlear implants are currently limited by current spread within the cochlea, which causes low spectral resolution of auditory nerve stimulation. Different cochlear implant makes vary in electrode...
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Tumor-Treating Fields Inhibit the Metastatic Potential of Osteosarcoma Cells: Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. The prognosis of metastatic osteosarcoma (OS) remains poor with a <20% survival rate, particularly in cases of distant (non-lung) metastases. Tumor-treating field (TTF) therapy is a novel electric field-based treatment that causes metaphase arrest and tumor cell death, with the advantage of reduced side effects compared to radiation...
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circUSP42 Is Downregulated in Triple-Negative Breast Cancer and Associated With Poor Prognosis: Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. We previously showed that microRNA-182 (miR-182) might promote cell proliferation and migration in triple-negative breast cancer (TNBC). This study aimed to investigate circular RNAs (circRNAs) that interact with miR-182 and play important roles in TNBC. Thirty patients with TNBC were enrolled. One pair of tumor and...
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Comparison of Ultrasonography and CT for Determining the Preoperative Benign or Malignant Nature of Thyroid Nodules: Diagnostic Performance According to Calcification: Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Background:The present study was designed to investigate the presence or absence of calcification and whether calcification size affect the diagnostic accuracy of ultrasonography (US) and computed tomography (CT) in predicting the benign or malignant...
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Two-Level Factorial Pre-TomoBreast Pilot Study of Tomotherapy and Conventional Radiotherapy in Breast Cancer: Post Hoc Utility of a Mean Absolute Dose Deviation Penalty Score: Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Background:A 2-level factorial pilot study was conducted in 2007 just before starting a randomized clinical trial comparing tomotherapy and conventional radiotherapy (CR) to reduce cardiac and pulmonary adverse effects in breast cancer,...
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Association of APOE e2 genotype with Alzheimer's and non-Alzheimer's neurodegenerative pathologies:
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Pathogenic variant in NFIX gene affecting three sisters due to paternal mosaicism: AbstractWe present a family with three girls presenting similar dysmorphic features, including overgrowth, intellectual disability, macrocephaly, prominent forehead, midface retrusion, strabismus, and scoliosis. Both parents were unaffected, suggesting the presence of an autosomal recessive syndrome. Following exome sequencing, a heterozygous nonsense variant was identified in the NFIX gene in all three siblings. The...
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Ophthalmological abnormalities in Down syndrome among Brazilian patients: AbstractDown syndrome is the most common chromosomal disorder, affecting 1/700 live births. Among the clinical findings, one constant concern is the high prevalence of visual disorders that, if left untreated, can negatively affect child development. The aim of this study was to determine the prevalence of ophthalmological findings among patients who attended an outpatient clinic for patients with Down syndrome in southern...
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Removal of a Silicone Gel Breast Implant in a Multiple Myeloma Patient Improved Disease Status: A Case Report: A 52-year-old African-American woman with a prior history of monoclonal gammopathy of undetermined significance (MGUS) developed infiltrating ductal carcinoma of the left breast. Following a mastectomy, she underwent reconstruction with a silicone gel breast implant. Three years later, her MGUS had progressed to active multiple myeloma (MM). She had a minimal response after two different...
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Successful Resection of a Giant Pulmonary Colloid Adenocarcinoma via Median Sternotomy: We report on a giant pulmonary colloid adenocarcinoma successfully resected using a median sternotomy approach. A 69-year-old woman visited our hospital owing to a giant mass detected on chest radiography. A giant cystic mass measuring 115 × 90 mm was detected in the right upper lung using computed tomography. We suspected mucinous adenocarcinoma and performed right upper lobectomy and mediastinal lymph node dissection...
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Cutaneous Adnexal Carcinoma with Apocrine Differentiation: A Challenging Diagnosis and Personalized Treatment with mTOR Inhibitor in a Very Rare Disease: Cutaneous adnexal carcinoma with apocrine differentiation is a rare neoplasm arising from cutaneous adnexa, especially of the head and neck and trunk region. Because of its rarity, the diagnosis is challenging and often impossible to distinguish from metastatic cutaneous adenocarcinoma of the breast. The standard of care remains surgery for resectable...
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A Rare Case of Neglected Rupture of Right Axillary Artery Pseudoaneurysm Mimicking a Soft Tissue Tumor: Traumatic lesions of the axillary artery itself are limited to 2.9–9% of major arterial injuries. Pseudoaneurysms represent a pulsating encapsulated hematoma in communication with the lumen of a ruptured vessel. Traumatic pseudoaneurysm of the axillary artery is a rare sequela of injury to the shoulder region. We describe a case of posttraumatic pseudoaneurysm involving the axillary artery, which...
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Endocranial anatomy of the ceratopsid dinosaur Triceratops and interpretations of sensory and motor function: Triceratops is one of the well-known Cretaceous ceratopsian dinosaurs. The ecology of Triceratops has been controversial because of its unique morphological features. However, arguments based on brain and inner ear structures have been scarce. In this study, two braincases (FPDM-V-9677 and FPDM-V-9775) were analyzed with computed tomography to generate three-dimensional virtual renderings...
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Isolated cranial nerve six palsy in two patients with COVID-19 infection: No abstract available View allThe abducens nerve (or abducent nerve) is the sixth cranial nerve (CNVI), in humans, that controls the movement of the lateral rectus muscle, responsible for outward gaze.Innervates: lateral rectus muscleFrom: abducens nucleusLatin: nervus abducensAbducens nerve - Wikipedia
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Axillary lymph node metastasis: Fine‐needle aspiration biopsy sensitivity as a function of node size, percent replacement of lymph node by tumor and tumor deposit size: AbstractBackgroundFine‐needle aspiration (FNA) is commonly used to investigate lymphadenopathy of suspected metastatic origin. While diagnostic accuracy of FNA for lymph node disease is well described, the relationship between node size, percent tumor replacement, and size of metastatic deposit with diagnostic accuracy is less well...
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Alzheimer's‐related cerebrovascular disease in Down syndrome: ObjectivesAdults with Down syndrome (DS) develop Alzheimer's disease (AD) pathology by their fifth decade. Compared with the general population, traditional vascular risks in adults with DS are rare, allowing examination of cerebrovascular disease in this population and insight into its role in AD without the confound of vascular risk factors. We examined in vivo MRI‐based biomarkers of cerebrovascular pathology in adults with DS, and...
07:51
New developments in respiratory medicine: a primary immunodeficiency perspective: Purpose of review To consider recent developments in respiratory medicine that are of relevance to clinicians caring for adults affected by primary immunodeficiency disorders. Recent findings We consider impulse oscillometry, new bronchoscopic techniques for sampling, MRI and PET, the concept of the human airway microbiome, and new treatment approaches for bronchiectasis and interstitial lung disease to better understand...
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Primary immune regulatory disorders: a growing universe of immune dysregulation: Purpose of review Primary immune regulatory disorders (PIRD) are a growing subset of diseases referred to as inborn errors of immunity. Unlike classical primary immune deficiency disorders that typically present with severe, recurrent, or unusual infections, the clinical manifestations of PIRD are dominated by immune-mediated diseases (autoimmunity, autoinflammation/hyperinflammation, lymphoproliferation, malignancy,...
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The Management of Foreign Body Displacement into the Maxillary Sinus as a Complication of Maxillofacial Interventions: Systematic Review: AbstractDisplacement of foreign bodies into the maxillary sinus shows an increasing tendency, especially in regard to raising amount of dental implant installation procedures. The purpose of our study was to compare the efficiency and the rate of late complications among the methods of removal of foreign bodies from maxillary sinus. We performed a systematic review...
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Long noncoding RNA MCM3AP antisense RNA 1 is downregulated in chronic obstructive pulmonary disease and regulates human bronchial smooth muscle cell proliferation: Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectivesThis study aimed to investigate the involvement of MCM3AP antisense RNA 1 (MCM3AP-AS1) in chronic obstructive pulmonary disease (COPD).MethodsThe expression levels of plasma MCM3AP-AS1 in COPD patients and healthy controls were measured by quantitative...
07:49
Circular RNA circ-NCOR2 accelerates papillary thyroid cancer progression by sponging miR-516a-5p to upregulate metastasis-associated protein 2 expression: Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectivePapillary thyroid cancer (PTC) is one of the most prevalent endocrine malignancies and the fifth most common cancer in women. Circular RNAs (circRNAs) have been shown to play vital functions in cancers, but few studies have focused on the functions and mechanism...
07:48
Role of the Hippo signaling pathway in safflower yellow pigment treatment of paraquat-induced pulmonary fibrosis: Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectiveTo elucidate the molecular mechanisms by which safflower yellow (SY) mediates therapeutic effects in rats with paraquat intoxication-induced pulmonary fibrosis.MethodsRats received combinations of paraquat, SY, and SB431542, a transforming growth factor (TGF)-β1 receptor antagonist. Survival over 28...
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A rare case of schwannomatosis of the extremities: Journal of International Medical Research, Volume 48, Issue 9, September 2020. A schwannoma is a benign tumor that arises from the myelin-producing Schwann cells that surround nerves. We herein report a case involving a 55-year-old man who first presented to our clinic with a schwannoma of the posterior tibial nerve and 5 years later with a schwannoma of the ulnar nerve. This is the first report of schwannomatosis of the ulnar and posterior tibial...
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Deferasirox, an iron-chelating agent, alleviates acute lung inflammation by inhibiting neutrophil activation and extracellular trap formation: Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectiveReactive oxygen species (ROS) production by neutrophils induces pulmonary endothelial cell damage and results in acute lung injury (ALI). We previously reported that deferasirox (DFS), an iron-chelating agent, inhibits the ROS production and neutrophil extracellular trap...
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Giant axillary tumor resection using ultrasound-guided interscalene brachial plexus block and serratus anterior plane block: Journal of International Medical Research, Volume 48, Issue 9, September 2020. Herein, we report the combined use of interscalene brachial plexus block and serratus anterior plane block for surgical removal of a large neoplasm that was embedded deep in the axilla and chest wall of a patient with high-risk hypertension. With the combined use of conventional and novel nerve blocks,...
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Changes in global DNA methylation and hydroxymethylation in oral mucosa according to tobacco smoke exposure: Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectiveThis prospective clinical study comparatively investigated the effects of tobacco smoking on global methylation and hydroxymethylation in oral epithelial cells.MethodsBuccal cells from the inside of the cheeks were collected from 47 individuals, including smokers, former smokers, and never smokers. DNA...
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Patterns of supraclavicular area failure after mastectomy in breast cancer patients: implications for target volume delineation: Journal of International Medical Research, Volume 48, Issue 9, September 2020. PurposeTo characterize the pattern of post-mastectomy supraclavicular lymph node (LN) metastases in patients with breast cancer (BC) and to provide insights for individualized clinical target volume delineation for radiotherapy.MethodsWe retrospectively analyzed 88 patients with BC who developed...
07:46
Association of −344C/T polymorphism in the aldosterone synthase (CYP11B2) gene with cardiac and cerebrovascular events in Chinese patients with hypertension: Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectiveSeveral recent studies have shown that the aldosterone synthase gene (CYP11B2) −344C/T polymorphism is related to cardiovascular diseases. However, whether the −344C allele influences the incidence of cardiovascular diseases in Chinese patients with hypertension...
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Efficacy of different treatment times of mild cerebral hypothermia on oxidative factors and neuroprotective effects in neonatal patients with moderate/severe hypoxic–ischemic encephalopathy: Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectiveTo investigate the efficacy of different treatment times of mild cerebral hypothermia for treating moderate/severe hypoxic–ischemic encephalopathy (HIE) in neonatal patients and its effects on oxidative factors.MethodsThis...
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Comparison of transradial coronary intervention for left main bifurcation disease using the new Braidin® slender 7 Fr sheath and a standard 6 Fr sheath: Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectivesTo compare the effectiveness and safety of the Braidin® slender 7 Fr sheath with a standard 6 Fr sheath for treating left main bifurcation disease.MethodsFrom January 2017 to March 2019, 277 patients with left main bifurcation disease who underwent the transradial...
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Safety and feasibility of trial of labor in pregnant women with cesarean scar diverticulum: Journal of International Medical Research, Volume 48, Issue 9, September 2020. ObjectiveLiterature on trial of labor after cesarean section (TOLAC) in women with isthmoceles is scarce because of complications associated with the procedure. This study investigated TOLAC's safety and feasibility in patients with isthmoceles.MethodsThe study group comprised 34 pregnant women with isthmoceles who vaginally delivered....
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Potential COVID-19 papain-like protease PLpro inhibitors: repurposing FDA-approved drugs: Using the crystal structure of SARS-CoV-2 papain-like protease (PLpro) as a template, we developed a pharmacophore model of functional centers of the PLpro inhibitor-binding pocket. With this model, we conducted data mining of the conformational database of FDA-approved drugs. This search identified 147 compounds that can be potential inhibitors of SARS-CoV-2 PLpro. The conformations of these compounds underwent...
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Mesenchymal stem cell exosomes reverse acute lung injury through Nrf-2/ARE and NF-κB signaling pathways: Acute lung injury (ALI) is associated with histopathological diffuse alveolar damage. The potential role of mesenchymal stem cells (MSCs) in the treatment of various clinical disorders have been widely documented, such as those for ALI. Recent evidence has demonstrated that exosomes from endothelial progenitor cells can improve outcomes of the lipopolysaccharide (LPS)-induced ALI. However, there...
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Anamnesis as a Prognostic Factor in Cochlear Implantation in Adults: Introduction: This study aims to analyze possible preoperative factors taken from the medical history that may assist the otolaryngologist in counseling an adult patient before cochlear implantation (CI). Objective: Analysis of preoperative factors taken during the initial patient presentation for a possible prognostic role in the auditory rehabilitation outcome. Methods: A cohort of 232 (272 CI implantations) postlingually deafened...
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PathogensPathogens, Vol. 9, Pages 769: Effects o...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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