Wednesday, April 10, 2019

Medicine


Gelesis Presents Preclinical Data Showing Proprietary Hydrogel Prevents Harmful Effects of a High-Fat Diet
BOSTON--(BUSINESS WIRE)--Gelesis announced preclinical data suggesting that its proprietary hydrogel, Gel-B, prevents the harmful effects of a high-fat diet on the liver.
Business Wire Health: Clinical Trials News
09:05
Gilead Presents New Data in Nonalcoholic Steatohepatitis (NASH) at the International Liver Congress™ 2019
FOSTER CITY, Calif.--(BUSINESS WIRE)--Gilead Sciences, Inc. (Nasdaq: GILD) today announced new data from the company's clinical research program in nonalcoholic steatohepatitis (NASH) being presented at The International Liver Congress™ 2019 in Vienna. The data support Gilead's efforts to develop combination therapies to target different aspects of NASH, evaluate the utility of noninvasive tests for the identification of patients living with the disease and advance overall understanding of the
Business Wire Health: Clinical Trials News
09:00
Correction to: Sinus augmentation analysis of the gradient of graft consolidation: a split-mouth histomorphometric study
Figure 1 was reused with permission from "Wiley", the publisher of a previous article by the same authors, DOI:10.1111/cid.12518.
Clinical Oral Investigations
03:00
Disrupted structural brain connectome underlying the cognitive deficits in remitted late-onset depression
Abstract Cognitive deficit is a key feature of late-onset depression (LOD) and remains after clinical recovery. LOD has been associated with widespread neurobiological difficulties, including atrophy in gray and white matter (WM) tissue in areas distributed throughout the brain. However, little is known about the topological pattern changes of WM structural networks in LOD in the remitted state and its relationship to cognitive deficits. We acquired diffusion tensor images in 37...
Latest Results for Brain Imaging and Behavior
03:00
Irregular structural networks of gray matter in patients with type 2 diabetes mellitus
Abstract Type 2 diabetes mellitus (T2DM) induces dementia and cognitive decrements indicating the impairment of the central nervous system. While there is evidence showing abnormalities in white-matter structural networks in T2DM, the topological features of gray matter are still unknown. The study enrolled 30 right-handed T2DM patients and 20 healthy control subjects with matched age, gender, handedness, and education. Graph theoretical analysis of magnetic resonance imaging on...
Latest Results for Brain Imaging and Behavior
03:00
Dose-intensified chemoradiation is associated with altered patterns of failure and favorable survival in patients with newly diagnosed glioblastoma
Abstract Background and purpose We evaluated whether dose-intensified chemoradiation alters patterns of failure and is associated with favorable survival in the temozolomide era. Materials and methods Between 2003 and 2015, 82 patients with newly diagnosed glioblastoma were treated with 66–81 Gy in 30 fractions using conventional magnetic resonance imaging....
Latest Results for Journal of Neuro-Oncology
03:00
Provention Bio Initiates Phase 3 PROTECT Clinical Trial with PRV-031 (Teplizumab) in Patients with Recent Onset Type 1 Diabetes
OLDWICK, N.J., April 9, 2019 /PRNewswire/ -- Provention Bio, Inc. (Nasdaq: PRVB), a clinical stage biopharmaceutical company dedicated to intercepting and preventing immune-mediated diseases, today announced that it has dosed the first patient in...
Drugs.com - Clinical Trials
Tue Apr 09, 2019 07:04
Spring is a good time to talk about oral cancer - The Harvell gazette
Spring is a good time to talk about oral cancer  The Harvell gazetteEvery April, the American Dental Association, the Massachusetts Dental Society and state-level dental groups across the nation promote Oral Cancer ...
Cancer of Tongue - Google News
08:00
Day of Hope - Kurt Brown makes a comeback from near quadriplegia, with help from Mission Hope - Santa Ynez Valley News
Day of Hope - Kurt Brown makes a comeback from near quadriplegia, with help from Mission Hope  Santa Ynez Valley NewsKurt Brown's long-term relationship with multiple myeloma landed him on reality's doorstep when the cancer deteriorated neck vertebrae to the point of failure.
Cancer of Tongue - Google News
Sun Apr 07, 2019 17:00
Potent stimulation of eosinopoiesis in murine bone-marrow by myriadenolide is mediated by cysteinyl-leukotriene signaling.
We describe the potent effect of myriadenolide (Myr), a naturally occurring labdane diterpene, in promoting the production of eosinophils in cultured bone-marrow from several inbred mouse strains. This enhancing effect is lineage-selective and requires the eosinophil growth factors, Interleukin(IL)-5 or GM-CSF. Myr acts over a very low concentration range (10-10-10-14 M), if added at the beginning of the cell cultivation. Its enhancing effect increases between 24 h and 10 days of culture. We used...
International Immunopharmacology
Sat Apr 06, 2019 00:00
Antioxidants, Vol. 8, Pages 96: Water- and Fat-Soluble Antioxidants in Human Seminal Plasma and Serum of Fertile Males
Antioxidants, Vol. 8, Pages 96: Water- and Fat-Soluble Antioxidants in Human Seminal Plasma and Serum of Fertile Males Antioxidants doi: 10.3390/antiox8040096 Authors: Giacomo Lazzarino Ilaria Listorti Gabriele Bilotta Talia Capozzolo Angela Maria Amorini Salvatore Longo Giuseppe Caruso Giuseppe Lazzarino Barbara Tavazzi Pasquale Bilotta Reactive oxygen species (ROS) are physiologically involved in functions like sperm maturation, capacitation and acrosome...
Antioxidants
03:00
Mild Traumatic Brain Injury Affects Cognitive Processing and Modifies Oscillatory Brain Activity during Attentional Tasks
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Apr 10, 2019 10:00
Pharmacological Optimization for Successful Traumatic Brain Injury Drug Development
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Apr 10, 2019 10:00
Mild Closed-Head Injury in Conscious Rats Causes Transient Neurobehavioral and Glial Disturbances: A Novel Experimental Model of Concussion
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Apr 10, 2019 10:00
Risk of Intracranial Complications in Minor Head Injury: The Role of Loss of Consciousness and Post-Traumatic Amnesia in a Multi-Center Observational Study
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Apr 10, 2019 10:00
Unbiased Recursive Partitioning to Stratify Patients with Acute Traumatic Spinal Cord Injuries: External Validity in an Observational Cohort Study
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Apr 10, 2019 10:00
Key Glycolytic Metabolites in Paralyzed Skeletal Muscle Are Altered Seven Days after Spinal Cord Injury in Mice
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
Wed Apr 10, 2019 10:00
The future of perioperative therapy in advanced renal cell carcinoma: how can we PROSPER?
Future Oncology, Ahead of Print.
Future Oncology
Wed Apr 10, 2019 13:22
RATIONALE 301 study: tislelizumab versus sorafenib as first-line treatment for unresectable hepatocellular carcinoma
Future Oncology, Ahead of Print.
Future Oncology
Wed Apr 10, 2019 05:08
Nanobiotix announces its clinical registration plan in Head and Neck cancers for the United States following FDA feedback - Associated Press
Nanobiotix announces its clinical registration plan in Head and Neck cancers for the United States following FDA feedback  Associated PressPress release *content* from Globe Newswire. The AP news staff was not involved in its creation.
Cancer of Hypopharynx - Google News
Tue Mar 26, 2019 09:00
Assessment of Pain, Acceptance of Illness, Adjustment to Life, and Strategies of Coping with Illness among Patients with Gastric Cancer
Abstract Gastric cancer is the fourth leading cause of deaths in Poland. The standard treatment for non-advanced gastric cancer is surgery, which significantly reduces the quality of life of patients. The objective of the study was to evaluate the strategy of coping with pain and its control, acceptance of illness, and adjustment to living with cancer in patients suffering from gastric cancer. The analysis of the impact of socio-economic factors on the above-mentioned problems...
Journal of Cancer Education
03:00

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