Sunday, February 3, 2019

Rapid Nickel(II)-Promoted Cysteine S-Arylation with Arylboronic Acids

Chem. Commun., 2019, Accepted Manuscript
DOI: 10.1039/C9CC00159J, Communication
Kengo Hanaya, Jun Ohata, Mary K. Miller, Alicia E. Mangubat-Medina, Michael J. Swierczynski, David C. Yang, Reece M. Rosenthal, Brian V. Popp, Zachary Thomas Ball
S-Arylation of cysteine residues is an increasingly powerful tool for site-specific modification of proteins, providing novel structure and electronic perturbation. The present work demonstrates an operationally-simple cysteine arylation reaction with...
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