Apparently Minor Head Trauma Can Lead to Anosmia: A Case Report

xlomafota13 shared this article with you from Inoreader Apparently Minor Head Trauma Can Lead to Anosmia: A Case Report Via O.R.L. Journal for oto-rhino-laryngology and its borderlands We report the case of a 49-year-old female patient who suffered from anosmia following an apparently mild head trauma when bumping into a door at her home. She reported no other accompanying symptoms after the injury that day. Olfactory function was completely lost, which was noted the day after the trauma. Gustatory function remained normal. Magnetic resonance imaging indicated lesions/bleeding in the right frontal lobe and in the area of the olfactory sulcus/bulb. The present case indicates that in case of apparently mild head trauma with anosmia, an MRI scan of the head should be performed because of suspect brain damage. This case also points to the deeper question how to gauge severity of head trauma. ORL View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Role of resection of torus tubarius to maximize the endonasal exposure of the inferior petrous apex and petroclival area

xlomafota13 shared this article with you from Inoreader Role of resection of torus tubarius to maximize the endonasal exposure of the inferior petrous apex and petroclival area Via Head & Neck Abstract Endoscopic access to the petrous apex and petroclival region often requires sacrificing the Eustachian tube (ET). This study aimed to compare the maximum exposure of the petrous apex and petroclival region via an endonasal corridor when sparing or resecting the ET and its torus. Six cadaveric specimens (12 sides) were dissected through an endonasal transpterygoid approach. Endonasal exposure of the petroclival region was completed using techniques that included the preservation of the ET (group 1), resection of the torus tubarius (group 2), and resection of the ET (group 3) were sequentially performed on each side. The working distances from the anterior genu of the petrous internal carotid artery (ICA) to the inferior boundaries of each corridor were measured and compared. In group 1, the medial petrous apex and petroclival sulcus could be exposed with a working distance of 4.08 ± 0.67 mm. In group 2, the fossa of Rosenmüller, inferior petrous apex, and hypoglossal canal could be exposed, with a significantly increased working distance of 18.33 ± 0.89 mm (P = .001). In group 3, the exposure and ICA control was superior and offered a working distance of 20.67 ± 0.78 mm. No statistically significant difference derived from comparing groups 2 and 3 (P = .875). Resection of the torus tubarius can increase exposure of the petrous apex and petroclival region. It provides an alternative to resecting the ET, which might be beneficial for maintenance of middle ear function. ET resection, however, seems superior when ICA control is required. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Brain mapping of auditory steady-state responses: A broad view of cortical and subcortical sources.

xlomafota13 shared this article with you from Inoreader Brain mapping of auditory steady-state responses: A broad view of cortical and subcortical sources. Via cortical auditory Related Articles Brain mapping of auditory steady-state responses: A broad view of cortical and subcortical sources. Hum Brain Mapp. 2020 Nov 09;: Authors: Farahani ED, Wouters J, van Wieringen A Abstract Auditory steady-state responses (ASSRs) are evoked brain responses to modulated or repetitive acoustic stimuli. Investigating the underlying neural generators of ASSRs is important to gain in-depth insight into the mechanisms of auditory temporal processing. The aim of this study is to reconstruct an extensive range of neural generators, that is, cortical and subcortical, as well as primary and non-primary ones. This extensive overview of neural generators provides an appropriate basis for studying functional connectivity. To this end, a minimum-norm imaging (MNI) technique is employed. We also present a novel extension to MNI which facilitates source analysis by quantifying the ASSR for each dipole. Results demonstrate that the proposed MNI approach is successful in reconstructing sources located both within (primary) and outside (non-primary) of the auditory cortex (AC). Primary sources are detected in different stimulation conditions (four modulation frequencies and two si des of stimulation), thereby demonstrating the robustness of the approach. This study is one of the first investigations to identify non-primary sources. Moreover, we show that the MNI approach is also capable of reconstructing the subcortical activities of ASSRs. Finally, the results obtained using the MNI approach outperform the group-independent component analysis method on the same data, in terms of detection of sources in the AC, reconstructing the subcortical activities and reducing computational load. PMID: 33166050 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Endotracheal Metallic Stent Removal: a Novel ABC (Airway Balloon Collapse) Technique

xlomafota13 shared this article with you from Inoreader Endotracheal Metallic Stent Removal: a Novel ABC (Airway Balloon Collapse) Technique Via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 10 November 2020 Source: International Journal of Pediatric Otorhinolaryngology Author(s): Shelagh A. Cofer, Joseph N. Badaoui, R. Paul Boesch, Karthik Balakrishnan View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

A 5-year-old boy with acute neurological disorder from anteflexion-induced cervical cord compression after tracheal surgery: radiological findings similar to Hirayama disease

xlomafota13 shared this article with you from Inoreader A 5-year-old boy with acute neurological disorder from anteflexion-induced cervical cord compression after tracheal surgery: radiological findings similar to Hirayama disease Via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 11 November 2020 Source: International Journal of Pediatric Otorhinolaryngology Author(s): Akinori Sekioka, Koji Fukumoto, Tatsuya Kawasaki, Masashi Koyama, Yoh Fujimoto, Hiromu Miyake, Akiyoshi Nomura, Susumu Yamada, Risa Kanai, Akihiro Makino, Naoto Urushihara View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

[Drug approval : entrectinib and larotrectinib - cancers with NTRK fusion].

xlomafota13 shared this article with you from Inoreader [Drug approval : entrectinib and larotrectinib - cancers with NTRK fusion]. Via Association française pour l'étude du cancer Related Articles [Drug approval : entrectinib and larotrectinib - cancers with NTRK fusion]. Bull Cancer. 2020 Nov;107(11):1085-1086 Authors: Delaye M, Rodrigues M PMID: 33169692 [PubMed - in process] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Lessons learned from Chernobyl and Fukushima on thyroid cancer screening and recommendations in case of a future nuclear accident.

xlomafota13 shared this article with you from Inoreader Lessons learned from Chernobyl and Fukushima on thyroid cancer screening and recommendations in case of a future nuclear accident. Via radioactive iodine Related Articles Lessons learned from Chernobyl and Fukushima on thyroid cancer screening and recommendations in case of a future nuclear accident. Environ Int. 2020 Nov 07;146:106230 Authors: Cléro E, Ostroumova E, Demoury C, Grosche B, Kesminiene A, Liutsko L, Motreff Y, Oughton D, Pirard P, Rogel A, Van Nieuwenhuyse A, Laurier D, Cardis E Abstract Exposure of the thyroid gland to ionizing radiation at a young age is the main recognized risk factor for differentiated thyroid cancer. After the Chernobyl and Fukushima nuclear accidents, thyroid cancer screening was implemented mainly for children, leading to case over-diagnosis as seen in South Korea after the implementation of opportunistic screening (where subjects are recruited at healthcare sites). The aim of cancer screening is to reduce morbidity and mortality, but screening can also cause negative effects on health (with unnecessary treatment if over-diagnosis) and on quality of life. This paper from the SHAMISEN special issue (Nuclear Emergency Situations - Improvement of Medical And Health Surveillance) presents the principles of cancer screening, the lessons learned from thyroid cancer screening, as well as the knowledge on thyroid cancer incidence after exposure to iodine-131. The SHAMISEN Consortium recommends to envisage systematic health screening after a nu clear accident, only when appropriately justified, i.e. ensuring that screening will do more good than harm. Based on the experience of the Fukushima screening, the consortium does not recommend mass or population-based thyroid cancer screening, as the negative psychological and physical effects are likely to outweigh any possible benefit in affected populations; thyroid health monitoring should however be made available to persons who request it (regardless of whether they are at increased risk or not), accompanied with appropriate information and support. PMID: 33171378 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Integrity of dural closure after autologous platelet rich fibrin augmentation: an in vitro study.

xlomafota13 shared this article with you from Inoreader Integrity of dural closure after autologous platelet rich fibrin augmentation: an in vitro study. Via leak of cerebrospinal fluid Related Articles Integrity of dural closure after autologous platelet rich fibrin augmentation: an in vitro study. Acta Neurochir (Wien). 2020 04;162(4):737-743 Authors: Vasilikos I, Beck J, Ghanaati S, Grauvogel J, Nisyrios T, Grapatsas K, Hubbe U Abstract BACKGROUND: Watertight closure of the dura mater is fundamental in neurosurgery. Besides the classical suturing techniques, a variety of biomaterials have been proposed as sealants. Platelet rich fibrin (PRF) is an autologous biomaterial which can readily be obtained through low-speed centrifugation of patient's own blood. It is rich in fibrin, growth factors, leucocytes and cytokines and has shown adhesive properties while promoting the physiological wound healing process. In this study, we investigated the effect of applying PRF in reinforcing the watertight dura mater closure. METHODS: We created an in vitro testing device, where the watertight dura mater closure could be hydrostatically assessed. On 26 fresh harvested bovine dura maters, a standardised 20-mm incision was closed with a running suture, and the leak pressure was measured first without (primary leak pressure) and then with PRF augmentation (secondary leak pressure). The two groups of measurements have been statistically analysed with the Student's paired t test. RESULTS: The "running suture only group" had a leak pressure of 10.5 ± 1.2 cmH2O (mean ± SD) while the "PRF-augmented group" had a leak pressure of 47.2 ± 2.6 cm H2O. This difference was statistically significant (p < 0.001; paired t test). CONCLUSIONS: Autologous platelet rich fibrin augmentation reliably reinforced watertight closure of the dura mater to a > 4-fold increased leak pressure after failure of the initial standard running suture technique. PMID: 32034495 [PubMed - indexed for MEDLINE] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

MR Myelography for the Detection of CSF-Venous Fistulas.

xlomafota13 shared this article with you from Inoreader MR Myelography for the Detection of CSF-Venous Fistulas. Via leak of cerebrospinal fluid Related Articles MR Myelography for the Detection of CSF-Venous Fistulas. AJNR Am J Neuroradiol. 2020 05;41(5):938-940 Authors: Chazen JL, Robbins MS, Strauss SB, Schweitzer AD, Greenfield JP Abstract CSF-venous fistula is an important treatable cause of spontaneous intracranial hypotension that is often difficult to detect using traditional imaging techniques. Herein, we describe the technical aspects and diagnostic performance of MR myelography when used for identifying CSF-venous fistulas. We report 3 cases in which the CSF-venous fistula was occult on CT myelography but readily detected using MR myelography. PMID: 32354709 [PubMed - indexed for MEDLINE] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Histopathological prognostic factors for colorectal liver metastases: A systematic review and meta-analysis of observational studies.

xlomafota13 shared this article with you from Inoreader Histopathological prognostic factors for colorectal liver metastases: A systematic review and meta-analysis of observational studies. Via Cellular and Molecular Biology Related Articles Histopathological prognostic factors for colorectal liver metastases: A systematic review and meta-analysis of observational studies. Histol Histopathol. 2020 Nov 09;:18274 Authors: de Oliveira CVC, Fonseca GM, Kruger JAP, de Mello ES, Coelho FF, Herman P Abstract INTRODUCTION: Resection is the mainstay of treatment for colorectal liver metastases (CRLMs). Many different histopathological factors related to the primary colorectal tumour have been well studied; however, histopathological prognostic factors related to CRLMs are still under evaluation. OBJECTIVE: To identify histopathological factors related to overall survival (OS) and disease-free survival (DFS) in patients with resected CRLMs. METHODS: A systematic review was performed with the following databases up to August 2020: PubMed, EMBASE, Web of Science, SciELO, and LILACS. The GRADE approach was used to rate the overall certainty of evidence by outcome. RESULTS: Thirty-three studies including 4,641 patients were eligible. We found very low certainty evidence that the following histopathological prognostic factors are associated with a statistically significant decrease in OS: presence of portal vein invasion (HR, 0,50 [95% CI, 0,37 to 0,68]; I²=0%), presence of perineural invasion (HR, 0,55 [95% CI, 0,36 to 0,83]; I²=0%), absence of pseudocapsule (HR, 0,41 [CI 95%, 0,29 to 0,57], p<0,00001; I²=0%), presence of satellite nodules (OR, 0,45 [95% CI, 0,26 to 0,80]; I²=0%), and the absence of peritumoural inflammatory infiltrate (OR, 0,20 [95% CI, 0,08 to 0,54]; I²=0%). Outcome data on DFS were scarce, except for tumour borders, which did not present a significant impact, precluding the meta-analysis. CONCLUSION: Of the histopathological prognostic factors studied, low- to moderate-certainty evidence shows that vascular invasion, perineural invasion, absence of pseudocapsule, presence of satellite nodules, and absence of peritumoral inflammatory infiltrate are associated with shorter overall survival in CRLMs. PMID: 33165892 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Anaplastic thyroid carcinoma: Updates on WHO classification, clinicopathological features and staging.

xlomafota13 shared this article with you from Inoreader Anaplastic thyroid carcinoma: Updates on WHO classification, clinicopathological features and staging. Via Cellular and Molecular Biology Related Articles Anaplastic thyroid carcinoma: Updates on WHO classification, clinicopathological features and staging. Histol Histopathol. 2020 Nov 10;:18277 Authors: Abe I, Lam AK Abstract Anaplastic thyroid carcinoma is an uncommon carcinoma representing 1 to 4 % of all thyroid cancers. The carcinoma is most common in females of the eight decades. It is a locally advanced cancer with frequent infiltration of surrounding organs, blood vessels and skin of neck. Paraneoplastic manifestations could occur. Approximately half of the patients with anaplastic thyroid carcinoma had distant metastasis with lung and brain as the most frequent sites of metastasis. The median survival of patients with anaplastic thyroid carcinoma reported was from 1 to 6 months. The current terminology of the cancer in World Health Organization is "anaplastic thyroid carcinoma" rather than "undifferentiated thyroid carcinoma". In the latest American Joint Committee on Cancer (AJCC) TNM staging system for anaplastic thyroid carcinoma, there are updates on T and N categories. To conclude, updated knowledge of clinicopathological features, classification, pathological staging will improve our understanding of the cancer and will help in the management of the patients with this aggressive cancer. PMID: 33170501 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Preoperative coronavirus testing

xlomafota13 shared this article with you from Inoreader [Preoperative coronavirus testing in Germany : Experiences with applying the recommendations of the German Society of Otorhinolaryngology, Head and Neck Surgery]. Via hno Related Articles [Preoperative coronavirus testing in Germany : Experiences with applying the recommendations of the German Society of Otorhinolaryngology, Head and Neck Surgery]. HNO. 2020 Nov 10;: Authors: Stuck BA, Demmler U, Hoffmann TK PMID: 33170313 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.